{"resolution": "", "ligand_mw": "", "secondary_structure": "GSNKGAIIGLM#CCCHHHHGGGC", "inchi": "", "method": "SOLUTION NMR", "ec_number": "", "uniprot_ac": "P05067", "remarks": "GSNKGAIIGLM, highly toxic synthetic derivative of amyloid beta-peptides", "description": "ABeta-(25-35), sequence GSNKGAIIGLM, is a highly toxic synthetic derivative of amyloid Beta-peptides (ABeta-peptides), which forms fibrillary aggregates. ABeta-(25-35) is investigated in a membrane-mimicking environment (HFIP/water 80/20 mixtures). Furthermore, a comparison with the solution structure of full-length amyloid peptides suggests a role for the 25-27 kink region, which appears to be a general feature of all peptides under the solution conditions explored.", "type": "Peptide", "ligand_smiles": "", "chain_id": "", "species": "Homo sapiens", "keyword": "11-mer peptide from Amyloid beta A4 protein", "ligstr": "", "pmid": "15293994", "mutation_s_field": "No", "author": "D'Ursi, A.M., Armenante, M.R., Guerrini, R., Salvadori, S., Sorrentino, G., Picone, D.", "pdb_id": "1QWP", "amyloid_non_amyloid": "Amyloid", "inchi_key": "", "ligand_name": "", "ligand_formula": "", "ligand_id": "", "r_value_free": "", "protein_name": "Amyloid-beta A4 protein", "gene_names": "", "global_stoichiometry": "", "alternative_name": "", "peptide_protein_sequence": "chain-ID A: GSNKGAIIGLM", "pdb_classification": "PROTEIN BINDING", "reference": "J Med Chem. 2004 Aug 12;47(17):4231-8", "length": "11", "entry": "S-0056"}