{"resolution": "1.51", "ligand_mw": "", "secondary_structure": "VQIVYK#CCCCCC&VQIVYK#CCCCCC", "inchi": "", "method": "X-RAY DIFFRACTION", "ec_number": "", "uniprot_ac": "P10636", "remarks": "Structure of an amyloid forming peptide VQIVYK from the repeat region of Tau", "description": "Amyloid fibrils formed from different proteins, each associated with a particular disease, contain a common cross-Beta spine. Structures of microcrystals all reveal steric zippers, but with variations that expand the range of atomic architectures for amyloid-like fibrils and offer an atomic-level hypothesis for the basis of prion strains.", "type": "Fibril", "ligand_smiles": "", "chain_id": "", "species": "Homo sapiens", "keyword": "VQIVYK peptide corresponding to residues 306-311 in the tau protein", "ligstr": "", "pmid": "17468747", "mutation_s_field": "No", "author": "Sawaya, M.R., Sambashivan, S., Nelson, R., Ivanova, M.I., Sievers, S.A., Apostol, M.I., Thompson, M.J., Balbirnie, M., Wiltzius, J.J., McFarlane, H.T., Madsen, A.O., Riekel, C., Eisenberg, D.", "pdb_id": "2ON9", "amyloid_non_amyloid": "Amyloid", "inchi_key": "", "ligand_name": "", "ligand_formula": "", "ligand_id": "", "r_value_free": "0.225", "protein_name": "Microtubule-associated protein tau", "gene_names": "", "global_stoichiometry": "Homo 4-mer - A4 ", "alternative_name": "", "peptide_protein_sequence": "chain-ID A: VQIVYK; chain-ID B: VQIVYK", "pdb_classification": "PROTEIN FIBRIL", "reference": "Nature. 2007 May 24;447(7143):453-7. Epub  2007 Apr 29", "length": "6", "entry": "S-0163"}