{"method": "X-RAY DIFFRACTION", "mutation_s_field": "W60V", "ec_number": "", "description": "The W60V mutant structural features are discussed, focusing on the roles of the DE loop and of residue 60 in relation to b2m structure and its amyloid aggregation trends.", "ligstr": "", "pmid": "19284997", "remarks": "structure of W60V beta-2 microglobulin mutant", "amyloid_non_amyloid": "Amyloid", "type": "Protein", "inchi": "", "resolution": "1.8", "species": "Homo sapiens", "secondary_structure": "MIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDVSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM#CCCBCCEEEEEEECCTTCTTCCEEEEEEEEEBSSCCEEEEEETTEECSCCCEEEEEECTTCCEEEEEEEECCCCTTCCEEEEEECTTCSSCEEEECCTTC", "chain_id": "", "gene_names": "B2M, CDABP0092, HDCMA22P", "r_value_free": "0.24100000", "pdb_id": "3EKC", "reference": "Biochem Biophys Res Commun. 2009 Mar 13;380(3):543-7.", "keyword": "Beta-2-microglobulin", "protein_name": "Beta-2-microglobulin", "ligand_formula": "", "peptide_protein_sequence": "chain-ID A: MIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDVSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM", "entry": "S-0223", "length": "100", "uniprot_ac": "P61769", "author": "Ricagno, S., Raimondi, S., Giorgetti, S., Bellotti, V., Bolognesi, M.", "ligand_smiles": "", "ligand_mw": "", "alternative_name": "", "ligand_name": "", "pdb_classification": "IMMUNE SYSTEM", "global_stoichiometry": "Monomer - A ", "inchi_key": "", "ligand_id": ""}