{"resolution": "1.61", "ligand_mw": "", "secondary_structure": "SSTNVG#CCCCCC", "inchi": "", "method": "X-RAY DIFFRACTION", "ec_number": "", "uniprot_ac": "P10997", "remarks": "Structure of an amyloid forming peptide SSTNVG from IAPP (alternate polymorph)", "description": "Polymorphic crystal structures of segments of prion and other amyloid proteins, which offer two structural mechanisms for the encoding of prion strains. In packing polymorphism, prion strains are encoded by alternative packing arrangements (polymorphs) of Beta-sheets formed by the same segment of a protein; in segmental polymorphism, prion strains are encoded by distinct Beta-sheets built from different segments of a protein. Both forms of polymorphism can produce enduring conformations capable of encoding strains.", "type": "Fibril", "ligand_smiles": "", "chain_id": "", "species": "Homo sapiens", "keyword": "SSTNVG FROM ISLET AMYLOID POLYPEPTIDE", "ligstr": "", "pmid": "19684598", "mutation_s_field": "No", "author": "Wiltzius, J.J., Landau, M., Nelson, R., Sawaya, M.R., Apostol, M.I., Goldschmidt, L., Soriaga, A.B., Cascio, D., Rajashankar, K., Eisenberg, D.", "pdb_id": "3FTR", "amyloid_non_amyloid": "Amyloid", "inchi_key": "", "ligand_name": "", "ligand_formula": "", "ligand_id": "", "r_value_free": "0.253", "protein_name": "Islet amyloid polypeptide", "gene_names": "", "global_stoichiometry": "Homo 4-mer - A4 ", "alternative_name": "", "peptide_protein_sequence": "chain-ID A: SSTNVG", "pdb_classification": "PROTEIN FIBRIL", "reference": "Nat Struct Mol Biol. 2009 Sep;16(9):973-8.", "length": "6", "entry": "S-0235"}