{"method": "X-RAY DIFFRACTION", "mutation_s_field": "No", "ec_number": "", "description": "They show that b2m can oligomerize and fibrillize via three-dimensional domain swapping. The hinge loop that connects the swapped domain to the core domain includes the fibrillizing segment LSFSKD, whose atomic structure was determined.", "ligstr": "", "pmid": "21131979", "remarks": "Crystal structure of Beta 2 Microglobulin amyloidogenic segment LSFSKD", "amyloid_non_amyloid": "Amyloid", "type": "Fibril", "inchi": "", "resolution": "1.8", "species": "Homo sapiens", "secondary_structure": "LSFSKD#CEEECC&LSFSKD#CEEECC&LSFSKD#CEEECC&LSFSKD#CEEECC", "chain_id": "", "gene_names": "", "r_value_free": "0.24100000", "pdb_id": "3LOZ", "reference": "Nat Struct Mol Biol. 2011 Jan;18(1):49-55.", "keyword": "Beta-2-microglobulin segment LSFSKD", "protein_name": "Beta-2-microglobulin", "ligand_formula": "", "peptide_protein_sequence": "chain-ID A: LSFSKD; chain-ID B: LSFSKD; chain-ID C: LSFSKD; chain-ID D: LSFSKD", "entry": "S-0266", "length": "6", "uniprot_ac": "P61769", "author": "Liu, C., Sawaya, M.R., Eisenberg, D.", "ligand_smiles": "", "ligand_mw": "", "alternative_name": "", "ligand_name": "", "pdb_classification": "PROTEIN FIBRIL", "global_stoichiometry": "Homo 8-mer - A8 ", "inchi_key": "", "ligand_id": ""}