{"method": "X-RAY DIFFRACTION", "mutation_s_field": "K11V", "ec_number": "", "description": "They identify a segment of the amyloid-forming protein AlphaB crystallin, which forms an oligomeric complex exhibiting properties of other amyloid oligomers: Beta-sheet-rich structure, cytotoxicity, and recognition by an oligomer-specific antibody. The x-ray-derived atomic structure of the oligomer reveals a cylindrical barrel, formed from six antiparallel protein strands, that was termed cylindrin. ", "ligstr": "", "pmid": "22403391", "remarks": "Amyloid-related segment of alphaB-crystallin residues 90-100", "amyloid_non_amyloid": "Amyloid", "type": "Fibril", "inchi": "", "resolution": "2.56", "species": "Homo sapiens", "secondary_structure": "KVKVLGDVIEV#CCCCCCCCCCC", "chain_id": "", "gene_names": "", "r_value_free": "0.27", "pdb_id": "3SGO", "reference": "Science. 2012 Mar 9;335(6073):1228-31.", "keyword": "Alpha-crystallin B chain", "protein_name": "Alpha-crystallin B chain", "ligand_formula": "", "peptide_protein_sequence": "chain-ID A: KVKVLGDVIEV", "entry": "S-0299", "length": "11", "uniprot_ac": "P02511", "author": "Laganowsky, A., Liu, C., Sawaya, M.R., Whitelegge, J.P., Park, J., Zhao, M., Pensalfini, A., Soriaga, A.B., Landau, M., Teng, P.K., Cascio, D., Glabe, C., Eisenberg, D.", "ligand_smiles": "", "ligand_mw": "", "alternative_name": "", "ligand_name": "", "pdb_classification": "PROTEIN FIBRIL", "global_stoichiometry": "Homo 6-mer - A6 ", "inchi_key": "", "ligand_id": ""}