{"resolution": "1.9", "ligand_mw": "", "secondary_structure": "YVVFL#CEEEC&YVVFL#CEEEC", "inchi": "", "method": "X-RAY DIFFRACTION", "ec_number": "", "uniprot_ac": "", "remarks": "[Leu-5]-Enkephalin mutant - YVVFL", "description": "[YVVFL fibril structure] The peptides YVVFL form oligomers and amyloid-like fibrils. YVVFV shows an early stage oligomer distribution similar to those of the previous two, but amyloid-like aggregates are less abundant. Atomic resolution X-ray structures of YVVFV show two different modes of interactions at the dry interface between steric zippers and pairs of antiparallel Beta-sheets, but both are less favorable than the packing motif found in YVVFL. Both YVVFV and YVVFL can form a Class 6 steric zipper. However, in YVVFV, the strands between mating sheets are parallel to each other and in YVVFL they are antiparallel. ", "type": "Fibril", "ligand_smiles": "", "chain_id": "", "species": "synthetic construct", "keyword": "[Leu-5]-Enkephalin mutant - YVVFL", "ligstr": "", "pmid": "24915112", "mutation_s_field": "No", "author": "Do, T.D., LaPointe, N.E., Sangwan, S., Teplow, D.B., Feinstein, S.C., Sawaya, M.R., Eisenberg, D.S., Bowers, M.T.", "pdb_id": "4ONK", "amyloid_non_amyloid": "Amyloid", "inchi_key": "", "ligand_name": "", "ligand_formula": "", "ligand_id": "", "r_value_free": "0.19899999", "protein_name": "Enkephalin mutant", "gene_names": "", "global_stoichiometry": "Homo 12-mer - A12 ", "alternative_name": "", "peptide_protein_sequence": "chain-ID A: YVVFL; chain-ID B: YVVFL", "pdb_classification": "PROTEIN FIBRIL", "reference": "J Phys Chem B. 2014 Jul 3;118(26):7247-56.", "length": "5", "entry": "S-0365"}