{"method": "X-RAY DIFFRACTION", "mutation_s_field": "No", "ec_number": "", "description": "They designed amyloid fibers capable of capturing carbon dioxide from flue gas, to address the global problem of excess anthropogenic carbon dioxide. By measuring dynamic separation of carbon dioxide from nitrogen, we show that fibers with designed amino acid sequences double the carbon dioxide binding capacity of the previously reported fiber formed by VQIVYK from Tau protein. In a second application, we designed fibers that facilitate retroviral gene transfer. By measuring lentiviral transduction, we show that designed fibers exceed the efficiency of polybrene, a commonly used enhancer of transduction.", "ligstr": "", "pmid": "25474758", "remarks": "VVTGVTA, an amyloid forming segment from alpha synuclein, residues 70-76", "amyloid_non_amyloid": "Amyloid", "type": "Fibril", "inchi": "", "resolution": "1.5", "species": "Homo sapiens", "secondary_structure": "VVTGVTA#CCCCCCC", "chain_id": "", "gene_names": "", "r_value_free": "0.27399999", "pdb_id": "4R0W", "reference": "J Am Chem Soc. 2014 Dec 31;136(52):18044-51.", "keyword": "Alpha-synuclein", "protein_name": "Alpha-synuclein", "ligand_formula": "", "peptide_protein_sequence": "chain-ID A: VVTGVTA", "entry": "S-0380", "length": "7", "uniprot_ac": "P37840", "author": "Li, D., Jones, E.M., Sawaya, M.R., Furukawa, H., Luo, F., Ivanova, M., Sievers, S.A., Wang, W., Yaghi, O.M., Liu, C., Eisenberg, D.S.", "ligand_smiles": "", "ligand_mw": "", "alternative_name": "", "ligand_name": "", "pdb_classification": "PROTEIN FIBRIL", "global_stoichiometry": "Homo 10-mer - A10 ", "inchi_key": "", "ligand_id": ""}