{"reference": "J Phys Chem B. 2016 Jul 7;120(26):5810-6.", "alternative_name": "", "entry": "S-0426", "gene_names": "", "remarks": "Structure of the amyloid forming peptide LVHSSN ", "secondary_structure": "LVHSSN#CCCCCC", "chain_id": "", "inchi": "", "amyloid_non_amyloid": "Amyloid", "pmid": "26629790", "ligand_smiles": "", "keyword": "LVHSSN (residues 16-21) from islet amyloid polypeptide", "peptide_protein_sequence": "chain-ID A: LVHSSN", "uniprot_ac": "", "protein_name": "Islet Amyloid Polypeptide", "r_value_free": "0.198", "mutation_s_field": "No", "ligand_mw": "", "pdb_id": "5E5Z", "inchi_key": "", "ec_number": "", "pdb_classification": "de novo protein", "type": "Fibril", "author": "Soriaga, A.B., Sangwan, S., Macdonald, R., Sawaya, M.R., Eisenberg, D.", "species": "Homo sapiens", "ligand_id": "", "method": "X-RAY DIFFRACTION", "ligand_name": "", "global_stoichiometry": "Homo 10-mer - A10", "resolution": "1.66", "ligand_formula": "", "length": "6", "ligstr": "", "description": "They determined four new crystal structures of segments within IAPP, all forming steric zippers. One of the segments in the fibril core of IAPP forms an out-of-register steric zipper. Analysis of this structure reveals several commonalities with previously solved out-of-register fibrils. These results provide additional evidence of out-of-register Beta sheets as a common structural motif in amyloid aggregates."}