{"reference": "Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11232-11236. Epub  2016 Sep 19", "alternative_name": "", "entry": "S-0433", "gene_names": "", "remarks": "Structure of NNQQNY from yeast prion Sup35 with zinc acetate determined by MicroED", "secondary_structure": "NNQQNY#CCCCCC", "chain_id": "A%%A", "inchi": "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)%%InChI=1S/Zn/q+2", "amyloid_non_amyloid": "Amyloid", "pmid": "27647903", "ligand_smiles": "CC(=O)O%%[Zn+2]", "keyword": "Eukaryotic peptide chain release factor GTP-binding subunit", "peptide_protein_sequence": "chain-ID A: NNQQNY", "uniprot_ac": "P05453", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit", "r_value_free": "0.19399999", "mutation_s_field": "No", "ligand_mw": "60.05%%65.41", "pdb_id": "5K2E", "inchi_key": "QTBSBXVTEAMEQO-UHFFFAOYSA-N%%PTFCDOFLOPIGGS-UHFFFAOYSA-N", "ec_number": "", "pdb_classification": "PROTEIN FIBRIL", "type": "Fibril", "author": "Sawaya, M.R., Rodriguez, J., Cascio, D., Collazo, M.J., Shi, D., Reyes, F.E., Hattne, J., Gonen, T., Eisenberg, D.S.", "species": "Saccharomyces cerevisiae", "ligand_id": "ACY%%ZN", "method": "ELECTRON CRYSTALLOGRAPHY", "ligand_name": "ACETIC ACID%%ZINC ION", "global_stoichiometry": "Homo 18-mer - A18 ", "resolution": "1.0", "ligand_formula": "C2 H4 O2%%Zn 2", "length": "6", "ligstr": "ACY:A:C2 H4 O2:60.05:ACETIC ACID:CC(=O)O:InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4):QTBSBXVTEAMEQO-UHFFFAOYSA-N;ZN:A:Zn 2:65.41:ZINC ION:[Zn+2]:InChI=1S/Zn/q+2:PTFCDOFLOPIGGS-UHFFFAOYSA-N", "description": "They show with four structures of the amyloid core of the Sup35 prion protein that, if the diffraction resolution is high enough, sufficiently accurate phases can be obtained by direct methods with the cryo-EM method microelectron diffraction (MicroED), just as in X-ray diffraction."}