{"resolution": "1.0", "ligand_mw": "59.04%%112.41", "secondary_structure": "NNQQNY#CCCCCC", "inchi": "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1%%InChI=1S/Cd/q+2", "method": "ELECTRON CRYSTALLOGRAPHY", "ec_number": "", "uniprot_ac": "P05453", "remarks": "Structure of NNQQNY from yeast prion Sup35 with cadmium acetate determined by MicroED", "description": "They show with four structures of the amyloid core of the Sup35 prion protein that, if the diffraction resolution is high enough, sufficiently accurate phases can be obtained by direct methods with the cryo-EM method microelectron diffraction (MicroED), just as in X-ray diffraction.", "type": "Fibril", "ligand_smiles": "CC(=O)[O-]%%[Cd+2]", "chain_id": "A%%A", "species": "Saccharomyces cerevisiae", "keyword": "Eukaryotic peptide chain release factor GTP-binding subunit", "ligstr": "ACT:A:C2 H3 O2 -1:59.04:ACETATE ION:CC(=O)[O-]:InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1:QTBSBXVTEAMEQO-UHFFFAOYSA-M;CD:A:Cd 2:112.41:CADMIUM ION:[Cd+2]:InChI=1S/Cd/q+2:WLZRMCYVCSSEQC-UHFFFAOYSA-N", "pmid": "27647903", "mutation_s_field": "No", "author": "Sawaya, M.R., Rodriguez, J., Cascio, D., Collazo, M.J., Shi, D., Reyes, F.E., Hattne, J., Gonen, T., Eisenberg, D.S.", "pdb_id": "5K2F", "amyloid_non_amyloid": "Amyloid", "inchi_key": "QTBSBXVTEAMEQO-UHFFFAOYSA-M%%WLZRMCYVCSSEQC-UHFFFAOYSA-N", "ligand_name": "ACETATE ION%%CADMIUM ION", "ligand_formula": "C2 H3 O2 -1%%Cd 2", "ligand_id": "ACT%%CD", "r_value_free": "0.242", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit", "gene_names": "", "global_stoichiometry": "Homo 18-mer - A18 ", "alternative_name": "", "peptide_protein_sequence": "chain-ID A: NNQQNY", "pdb_classification": "PROTEIN FIBRIL", "reference": "Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11232-11236. Epub  2016 Sep 19", "length": "6", "entry": "S-0434"}