{"global_stoichiometry": "Homo 10-mer - A10", "ligstr": "", "uniprot_ac": "P09651", "inchi": "", "reference": "Science. 2018 Feb 9;359(6376):698-701.", "author": "Hughes, M.P., Sawaya, M.R., Boyer, D.R., Goldschmidt, L., Rodriguez, J.A., Cascio, D., Chong, L., Gonen, T., Eisenberg, D.S.", "type": "Fibril", "ligand_id": "", "species": "Homo sapiens", "method": "X-RAY DIFFRACTION", "keyword": "hnRNPA1", "gene_names": "", "chain_id": "", "ligand_mw": "", "inchi_key": "", "secondary_structure": "GYNGFG#CCCSCC", "amyloid_non_amyloid": "Non-amyloid", "length": "6", "remarks": "GYNGFG from low-complexity domain of hnRNPA1, residues 243-248", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "peptide_protein_sequence": "chain-ID A: GYNGFG", "ligand_name": "", "ligand_smiles": "", "pdb_id": "6BXX", "ec_number": "", "pdb_classification": "PROTEIN FIBRIL", "mutation_s_field": "No", "ligand_formula": "", "r_value_free": "0.086", "alternative_name": "", "description": "They determined the atomic structures of five segments from protein low-complexity domains associated with membraneless assemblies. Their common structural feature is the stacking of segments into kinked Beta sheets that pair into protofilaments. Unlike steric zippers of amyloid fibrils, the kinked sheets interact weakly through polar atoms and aromatic side chains. GYNGFG from low-complexity domain of hnRNPA1, residues 243-248.", "resolution": "1.1", "pmid": "29439243", "entry": "S-0506"}