{"resolution": "3.2", "ligand_mw": "", "secondary_structure": "KNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF#CEEEEEESCEEEEEESCSSCEEEEEECCEECCCEEEESSEECCEEECCCCCEEEEEEEEEEEEEEEEEEESCCCEEEECCSSSCEEEEEEEEEC&KNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF#CEEEEEESCEEEEEESCSSCEEEEEECCEECCCEEEESSEECCEEECCCCCEEEEEEEEEEEEEEEEEEESCCCEEEECCSSSCEEEEEEEEEC&KNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF#CEEEEEESCEEEEEESCSSCEEEEEECCEECCCEEEESSEECCEEECCCCCEEEEEEEEEEEEEEEEEEESCCCEEEECCSSSCEEEEEEEEEC", "inchi": "", "method": "ELECTRON MICROSCOPY", "ec_number": "", "uniprot_ac": "P10636", "remarks": "Narrow Pick Filament from Pick's disease brain", "description": "The structures of tau filaments from patients with Pick's disease, a neurodegenerative disorder characterized by frontotemporal dementia. The filaments consist of residues Lys254-Phe378 of 3R tau, which are folded differently from the tau filaments in Alzheimer's disease, establishing the existence of conformers of assembled tau.", "type": "Fibril", "ligand_smiles": "", "chain_id": "", "species": "Homo sapiens", "keyword": "Microtubule-associated protein tau", "ligstr": "", "pmid": "30158706", "mutation_s_field": "No", "author": "Falcon, B., Zhang, W., Murzin, A.G., Murshudov, G., Garringer, H.J., Vidal, R., Crowther, R.A., Ghetti, B., Scheres, S.H.W., Goedert, M.", "pdb_id": "6GX5", "amyloid_non_amyloid": "Non-amyloid", "inchi_key": "", "ligand_name": "", "ligand_formula": "", "ligand_id": "", "r_value_free": "", "protein_name": "Microtubule-associated protein tau", "gene_names": "MAPT, MAPTL, MTBT1, TAU", "global_stoichiometry": "Homo 3-mer - A3 ", "alternative_name": "Neurofibrillary tangle protein, Paired helical filament-tau", "peptide_protein_sequence": "chain-ID A: KNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF; chain-ID B: KNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF; chain-ID C: KNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF", "pdb_classification": "PROTEIN FIBRIL", "reference": "Nature. 2018 Sep;561(7721):137-140.", "length": "94", "entry": "S-0551"}