MPAD: Membrane Protein complex binding Affinity Database

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Protein Information

Protein Complex

Protein 1

Protein 2

Source Organism

List of Organisms

PDB ID

List of IDs

UniProt ID

List of IDs

Oligomeric State

PDB structure known

Yes
No
All

Wild/Mutant

Wild-type Data :

Mutation Type :
Single
Double
Multiple

Mutation

to

Interface Residue

Yes
No
All

Membrane interface

Yes
No
All

Protein Type

Both are membrane proteins
Any one

Mutant Topology

Membrane protein type

No. of TM segments

Protein 1

Protein 2

Functional Class

Experimental Conditions

Experimental Technique

Temperature (K)

to

pH

to

Thermodynamic Parameters

Wild-type K_D (M)

to

Mutant K_D (M)

to

Wild-type ΔG (kcal/mol)

to

Mutant ΔG (kcal/mol)

to

ΔΔG (kcal/mol)

to

Literature Information

PubMed ID

Author

Journal

Year

to

Display Columns

Protein Information

Entry ID
PDB ID
Protein 1
Protein 2
Interacting Chains
UniProt ID
Source Organism
Protein Type
Oligomeric State
Mutation(s)
Mutation Type
Interface Residues
Membrane Interface

Membrane features

Structural Class
Functional Class
No. of TM segments
Mutant Topology
Membrane protein type

Experimental Conditions

Technique used
Temperature
Buffer Conditions
pH

Thermodynamic Parameters

Wild-type K_D (M)
Mutant K_D (M)
Wild-type k_on (1/Ms)
Mutant k_on (1/Ms)
Wild-type k_off (1/s)
Mutant k_off (1/s)
Wild-type ΔG (kcal/mol)
Mutant ΔG (kcal/mol)
ΔΔG (kcal/mol)

Literature

PubMed ID
DOI
Location
Authors
Title
Year
Volume
Pages
Journal
Data Source
Remarks

Result per page:

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The database is maintained by Protein Bioinformatics Lab,
Department of Biotechnology, Indian Institute of Technology Madras

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