PRA-MutPred

Protein-RNA complex Binding Affinity change Prediction

Dataset

Click here for training dataset
Click here for test dataset

Dataset used for training the model.

S.No	PDB	Mutation	Experimental ΔΔG(kcal/mol)	Source
1	2g4b	F262A	1.63	ProNAB
2	2g4b	F304A	1.7	ProNAB
3	2g4b	G301I	0.97	ProNAB
4	2g4b	F199A	1.31	ProNAB
5	2la5	R8K	2.27	ProNAB
6	2la5	R4K	1.44	ProNAB
7	2la5	G14L	0.2	ProNAB
8	2la5	G14A	1.52	ProNAB
9	2yh1	G319R	0.3	ProNAB
10	3zla	H93A	-1.43	ProNAB
11	3zla	M150T	-0.92	ProNAB
12	3zla	R81A	-0.82	ProNAB
13	3zla	K179A	-0.23	ProNAB
14	2li8	C161A	1.46	ProNAB
15	2xfm	F343A	1.425	ProNAB
16	2xfm	M382A	0.7	ProNAB
17	3moj	Y407A	0.47	ProNAB
18	3ncu	H847A	1.01	ProNAB
19	1zh5	D33I	1.73	ProNAB
20	1zh5	D33A	0.65	ProNAB
21	1zh5	D33E	0.0	ProNAB
22	1zh5	N56A	0.45	ProNAB
23	4qei	V513P	1.14	ProNAB
24	4qei	V441P	1.25	ProNAB
25	4o26	F376A	4.18	ProNAB
26	4o26	Y503A	1.5	ProNAB
27	2mjh	K313A	2.42	ProNAB
28	2mjh	L320S	1.89	ProNAB
29	2mjh	P228S	2.59	ProNAB
30	2mjh	R314K	0.17	ProNAB
31	2ru3	R103E	2.38	ProNAB
32	4m59	C449S	-0.01	ProNAB
33	4m59	C430S	0.76	ProNAB
34	4oe1	C279S	0.72	ProNAB
35	4m59	C279S	0.72	ProNAB
36	4m59	C256S	0.28	ProNAB
37	6d12	Y483F	0.09	ProNAB
38	6d12	Y483A	0.79	ProNAB
39	6d12	R496A	1.15	ProNAB
40	6d12	F451A	-0.04	ProNAB
41	6cyt	R259A	0.42	ProNAB
42	6cyt	W256A	-0.37	ProNAB
43	6cyt	R254A	0.8	ProNAB
44	6cyt	R251A	1.34	ProNAB
45	3v71	S441A	0.78	ProNAB
46	3v74	S554A	0.71	ProNAB
47	2lec	Q88A	0.02	ProNAB
48	2lec	R61A	3.27	ProNAB
49	2lec	D48A	0.61	ProNAB
50	2lec	Y44A	3.27	ProNAB
51	2lec	D76A	1.74	ProNAB
52	2lec	K17A	1.56	ProNAB
53	2leb	Q88A	0.16	ProNAB
54	2leb	R61A	3.15	ProNAB
55	2leb	S54A	0.2	ProNAB
56	2leb	D48A	0.69	ProNAB
57	2leb	Y44A	3.15	ProNAB
58	2leb	K17A	1.34	ProNAB
59	4qvi	M218L	6.6	ProNAB
60	4qg3	G219V	5.37	ProNAB
61	3u4m	T217V	3.63	ProNAB
62	3u4m	T217A	2.49	ProNAB
63	2mxy	H49A	1.8	ProNAB
64	2mxy	K50A	0.75	ProNAB
65	4z4d	A481T	0.52	ProNAB
66	4z4c	A481T	0.41	ProNAB
67	6b14	S97N	-1.87	ProNAB
68	1si2	F292A	3.8	ProNAB
69	1si2	L337A	2.98	ProNAB
70	1si2	R278A	1.67	ProNAB
71	5f98	H830A	0.07	ProNAB
72	5mpg	R55A	2.13	ProNAB
73	5mpg	D42A	0.6	ProNAB
74	5mpg	F23A	-0.2	ProNAB
75	5m8i	K105A	0.23	ProNAB
76	5m8i	Q103A	-0.02	ProNAB
77	5m8i	K101A	0.01	ProNAB
78	5m8i	F61A	-0.24	ProNAB
79	5m8i	H35A	-0.43	ProNAB
80	5m8i	Y34A	-0.49	ProNAB
81	5m8i	F32A	0.48	ProNAB
82	5wzh	Q410E	2.3	ProNAB
83	5wzh	F398A	2.62	ProNAB
84	6cmn	Q54A	0.61	ProNAB
85	6cmn	R52A	2.77	ProNAB
86	6cmn	R47K	3.37	ProNAB
87	6cmn	R47A	3.73	ProNAB
88	4r8i	H66Y	0.03	ProNAB
89	4r8i	S63Y	2.49	ProNAB
90	4r8i	S63F	2.3	ProNAB
91	4r8i	S21P	1.11	ProNAB
92	4r8i	R18K	-0.01	ProNAB
93	4r8i	K19A	4.96	ProNAB
94	4r8i	R18A	1.46	ProNAB
95	2xgj	E1033A	-0.2	ProNAB
96	2xgj	R1030A	-0.04	ProNAB
97	3wbm	R44A	1.48	ProNAB
98	3wbm	R42A	0.33	ProNAB
99	3wbm	Y22A	0.65	ProNAB
100	3wbm	K17A	0.0	ProNAB
101	4ed5	R147A	0.85	ProNAB
102	4ed5	R136A	0.95	ProNAB
103	4ed5	R97A	1.47	ProNAB
104	4ed5	T90A	0.66	ProNAB
105	4ed5	N21A	0.63	ProNAB
106	3uzs	H280A	0.51	ProNAB
107	2x1a	R87K	1.81	ProNAB
108	2x1a	R87A	1.81	ProNAB
109	2x1a	Y27A	1.53	ProNAB
110	2x1a	Y27F	6.28	ProNAB
111	2x1a	Y21A	1.0	ProNAB
112	5e3h	R791A	0.42	ProNAB
113	5e3h	K788A	-0.08	ProNAB
114	5e3h	Q784A	-0.02	ProNAB
115	6so9	Y596A	1.52	ProNAB
116	6so9	R591M	0.46	ProNAB
117	6so9	Q577A	0.09	ProNAB
118	6so9	F560A	1.96	ProNAB
119	6so9	N526A	0.27	ProNAB
120	6so9	H523A	1.46	ProNAB
121	6sdy	R209A	-0.01	ProNAB
122	6sdy	S208A	0.02	ProNAB
123	6ny5	R318E	1.11	ProNAB
124	6kwr	R277A	0.48	ProNAB
125	5h1l	Y474A	0.28	ProNAB
126	5h1l	F381A	0.76	ProNAB
127	5ip2	K81A	-0.02	ProNAB
128	5w1h	K1320A	-0.12	ProNAB
129	5w1h	K1305A	0.41	ProNAB
130	5w1h	K435A	-0.25	ProNAB
131	5w1h	H328A	0.04	ProNAB
132	5wlh	K1305A	0.46	ProNAB
133	5wlh	K435A	0.33	ProNAB
134	5wlh	H328A	0.42	ProNAB
135	5wlh	W325A	0.36	ProNAB
136	1ttt	E390A	1.06	ProNAB
137	1ttt	R389A	1.56	ProNAB
138	1ttt	K376A	0.12	ProNAB
139	1ttt	Q341A	1.6	ProNAB
140	1ttt	R339A	-0.09	ProNAB
141	1ttt	T332V	1.15	ProNAB
142	1ttt	H331V	1.14	ProNAB
143	1ttt	R330A	1.73	ProNAB
144	1ttt	R300A	0.41	ProNAB
145	1ttt	R274A	1.36	ProNAB
146	1ttt	T232V	0.0	ProNAB
147	1ttt	N91A	0.85	ProNAB
148	1ttt	Y88F	-0.04	ProNAB
149	1ttt	N64A	-0.14	ProNAB
150	1ttt	R59A	-0.04	ProNAB
151	1ttt	E56A	-0.09	ProNAB
152	5ztm	K229A	0.86	ProNAB
153	5ztm	H196E	2.09	ProNAB
154	5ztm	H196A	1.58	ProNAB
155	5ztm	E195A	-0.17	ProNAB
156	5ztm	N175A	1.09	ProNAB
157	5ztm	E172A	-0.06	ProNAB
158	5ztm	K171E	2.16	ProNAB
159	5ztm	K58A	1.44	ProNAB
160	5ztm	N29A	0.44	ProNAB
161	5ztm	S5A	1.28	ProNAB
162	5ztm	K4E	2.03	ProNAB
163	5ytv	N70A	0.32	ProNAB
164	5ytv	N67A	0.82	ProNAB
165	5ytv	D83A	0.53	ProNAB
166	5ytv	T89A	0.86	ProNAB
167	5jbj	H406A	0.03	ProNAB
168	5h1k	R33A	1.55	ProNAB
169	5h1k	F381D	2.65	ProNAB
170	5h1k	N13A	1.04	ProNAB
171	5h1k	M357A	2.09	ProNAB
172	5h1k	R359A	3.12	ProNAB
173	5h1k	R335E	3.56	ProNAB
174	5h1k	W14A	3.06	ProNAB
175	5h1k	W422E	2.62	ProNAB
176	5h1k	Y15A	2.02	ProNAB
177	5h1k	M403E	1.25	ProNAB
178	5m3h	R633A	0.82	ProNAB
179	5eim	T437A	1.58	ProNAB
180	5eim	R349A	0.95	ProNAB
181	5wwx	T362A	1.47	ProNAB
182	5wwx	K350A	0.99	ProNAB
183	2xs2	P39A	0.82	ProNAB
184	4ht9	Y25A	-0.3	ProNAB
185	4ht9	F42S	0.7	ProNAB
186	4ht8	Y25A	4.15	ProNAB
187	4ht8	F42S	0.55	ProNAB
188	1gtf	K40M	0.09	ProNAB
189	1gtf	K40L	2.75	ProNAB
190	1gtf	K40V	2.29	ProNAB
191	4v4f	K38V	2.4	ProNAB
192	5eeu	K40L	0.25	ProNAB
193	5eeu	K40V	1.0	ProNAB
194	5eeu	K40A	1.87	ProNAB
195	4r3i	R475F	1.3	ProNAB
196	4r3i	N367D	0.9	ProNAB
197	4rcj	R506A	1.31	ProNAB
198	4rcj	D401N	-1.59	ProNAB
199	4qvc	K31A	4.02	ProNAB
200	4qvc	N28A	1.025	ProNAB
201	4qvc	N48A	-0.155	ProNAB
202	3gib	K31A	2.89	ProNAB
203	3gib	N28A	2.2	ProNAB
204	3gib	N48A	1.95	ProNAB
205	2kfy	E84A	4.26	ProNAB
206	2kfy	W20A	4.26	ProNAB
207	2kg0	F184A	0.96	ProNAB
208	2kg0	E182A	2.82	ProNAB
209	2kg0	Y180A	1.5	ProNAB
210	2kg0	R179A	2.82	ProNAB
211	2kg0	K173A	0.54	ProNAB
212	2kg0	R116A	2.82	ProNAB
213	2jpp	R44A	5.14	ProNAB
214	2jpp	L4A	2.11	ProNAB
215	1ytu	K127A	1.2	ProNAB
216	1ytu	Y123A	0.97	ProNAB
217	1ytu	Q137A	0.73	ProNAB
218	1dfu	R9A	3.33	ProNAB
219	1dfu	S17A	0.0	ProNAB
220	5ho4	E183A	0.55	ProNAB
221	5ho4	F157A	0.91	ProNAB
222	5ho4	K120A	0.75	ProNAB
223	5ho4	K113A	1.16	ProNAB
224	5ho4	H108A	0.22	ProNAB
225	5ho4	E92A	1.11	ProNAB
226	5ho4	F66A	1.12	ProNAB
227	5ho4	D49A	0.94	ProNAB
228	5ho4	Q19A	0.79	ProNAB
229	3sn2	N685A	-0.29	ProNAB
230	3sn2	S681A	3.08	ProNAB
231	3sn2	K379R	1.3	ProNAB
232	3sn2	K379N	2.97	ProNAB
233	3sn2	S371D	2.86	ProNAB
234	3sn2	S371A	1.45	ProNAB
235	3gpq	Y114A	-5.01	ProNAB
236	3gpq	R144A	-3.47	ProNAB
237	3gpq	T111A	-3.41	ProNAB
238	3gpq	G32S	-3.72	ProNAB
239	3gpq	G32A	-4.14	ProNAB
240	1k8w	R181A	0.65	ProNAB
241	1k8w	R181M	-0.21	ProNAB
242	1k8w	R181K	0.0	ProNAB
243	1k8w	D90A	-0.35	ProNAB
244	1k8w	D90N	-0.35	ProNAB
245	1k8w	D90E	-0.35	ProNAB
246	3qsu	K33A	1.78	ProNAB
247	4cio	A110T	1.24	ProNAB
248	4cio	N108A	-0.18	ProNAB
249	4cio	N106A	0.49	ProNAB
250	4cio	K104M	0.09	ProNAB
251	4cio	R103M	0.86	ProNAB
252	4cio	N97A	-0.08	ProNAB
253	4cio	Y78F	1.49	ProNAB
254	4cio	K74M	-0.22	ProNAB
255	4cio	Y44A	1.61	ProNAB
256	4cio	Y44F	0.2	ProNAB
257	4cio	K36E	2.29	ProNAB
258	4cio	K36M	2.71	ProNAB
259	3am1	K215A	-0.08	ProNAB
260	3am1	K210A	0.64	ProNAB
261	3am1	K209A	-0.29	ProNAB
262	3am1	K207A	-0.7	ProNAB
263	3am1	K165A	-0.49	ProNAB
264	3am1	N161A	0.95	ProNAB
265	3am1	K123A	-0.37	ProNAB
266	3am1	K30A	-0.46	ProNAB
267	3am1	K26A	-0.15	ProNAB
268	2kxn	R190A	1.63	ProNAB
269	2kxn	F161A	1.63	ProNAB
270	2kxn	F123A	1.63	ProNAB
271	2kxn	T196A	1.2	ProNAB
272	2kxn	I195A	1.07	ProNAB
273	2kxn	S194A	0.23	ProNAB
274	2kxn	Y165F	1.1	ProNAB
275	2kxn	V137A	0.0	ProNAB
276	2kxn	R111A	0.31	ProNAB
277	1zdi	Y85A	3.58	ProNAB
278	Izdi	N55A	-0.23	ProNAB
279	Izdi	R49A	1.74	ProNAB
280	Izdi	K43A	-0.1	ProNAB
281	1zdi	K61A	3.88	ProNAB
282	1zdi	K57A	3.29	ProNAB
283	1zdi	N55A	1.03	ProNAB
284	1zdi	S53A	0.56	ProNAB
285	1zdi	R49A	3.92	ProNAB
286	1zdi	K43A	-0.51	ProNAB
287	2e9t	K18A	0.41	ProNAB
288	2e9t	K20E	0.34	ProNAB
289	2e9t	K18E	0.21	ProNAB
290	1feu	H85A	1.59	ProNAB
291	1feu	R19A	1.62	ProNAB
292	1feu	K14A	0.22	ProNAB
293	1feu	R10A	1.69	ProNAB
294	5udz	I167A	0.05	ProNAB
295	5udz	E151K	0.13	ProNAB
296	5udz	Y140A	0.92	ProNAB
297	5udz	H162A	0.88	ProNAB
298	5udz	H148A	0.68	ProNAB
299	5dno	N477A	1.77	ProNAB
300	5dno	Y466F	3.22	ProNAB
301	5dno	K436A	2.29	ProNAB
302	5dno	Y352F	2.23	ProNAB
303	5dno	R338A	1.83	ProNAB
304	5dno	N336A	1.73	ProNAB
305	5dno	S333A	1.57	ProNAB
306	4yvi	D169L	1.21	ProNAB
307	4yvi	D169E	0.69	ProNAB
308	4yvi	D169N	3.55	ProNAB
309	4yvi	R154K	2.04	ProNAB
310	4yvi	Y115F	2.03	ProNAB
311	4yvi	H200A	1.21	ProNAB
312	4yvi	D177A	1.59	ProNAB
313	4yvi	S170A	1.26	ProNAB
314	4yvi	D169A	1.72	ProNAB
315	4yvi	R154A	1.62	ProNAB
316	4yvi	G141A	1.35	ProNAB
317	4yvi	Y136A	1.12	ProNAB
318	4yvi	Y115A	2.1	ProNAB
319	4yvi	Q90A	1.21	ProNAB
320	4yvi	P89A	1.42	ProNAB
321	4yvi	Y86A	1.18	ProNAB
322	4yvi	G79A	1.76	ProNAB
323	4yvi	G55A	1.25	ProNAB
324	4qvd	K31A	1.0	ProNAB
325	4qvd	N28A	-0.01	ProNAB
326	4qvd	N48A	-1.64	ProNAB
327	4qvd	F42S	2.475	ProNAB
328	4qvc	Y25A	5.165	ProNAB
329	4qvc	F42S	1.74	ProNAB
330	4pmw	N796E	0.51	ProNAB
331	4pmw	Q790E	-0.08	ProNAB
332	4pmw	N796A	0.41	ProNAB
333	4pmw	Q790A	0.17	ProNAB
334	4pmw	N661A	-0.25	ProNAB
335	4nku	N165A	0.03	ProNAB
336	4nku	D160A	-0.14	ProNAB
337	4ngb	W1014A	0.54	ProNAB
338	4ngb	Y966F	2.15	ProNAB
339	4ngb	H982A	0.91	ProNAB
340	4ngb	Y961F	1.98	ProNAB
341	4ngb	R927A	1.91	ProNAB
342	4ngb	Y926A	2.15	ProNAB
343	4mdx	E78A	3.81	ProNAB
344	4mdx	S73A	2.73	ProNAB
345	4mdx	K53A	2.49	ProNAB
346	4mdx	R25A	2.34	ProNAB
347	4erd	R465A	1.69	ProNAB
348	4erd	Y407A	1.38	ProNAB
349	3vyy	N30A	0.53	ProNAB
350	3vyx	H207A	1.82	ProNAB
351	3l25	K319A	0.74	ProNAB
352	3l25	K309A	0.97	ProNAB
353	3l25	R305A	0.79	ProNAB
354	3k5y	H454A	1.23	ProNAB
355	3qgc	R288Y	-0.42	ProNAB
356	3qgb	R288Y	0.09	ProNAB
357	3k5y	R288A	1.03	ProNAB
358	3k5y	R364A	0.59	ProNAB
359	3k5y	H326A	1.05	ProNAB
360	3eqt	I597S	1.07	ProNAB
361	3eqt	E573A	1.79	ProNAB
362	2zzn	D223E	0.35	ProNAB
363	2zzn	N265H	0.35	ProNAB
364	2zzn	N265Q	0.09	ProNAB
365	2zzn	E185Q	0.09	ProNAB
366	2zzn	E185D	0.17	ProNAB
367	2zzn	R145A	0.24	ProNAB
368	2zzn	K137A	0.54	ProNAB
369	2zzn	D223A	0.24	ProNAB
370	2zzn	R186A	0.35	ProNAB
371	2zzn	Y177A	0.3	ProNAB
372	2zzn	R181A	0.17	ProNAB
373	2zzn	P267A	0.09	ProNAB
374	2zzn	N265A	0.09	ProNAB
375	2zzn	K318A	0.3	ProNAB
376	2zko	R44A	0.81	ProNAB
377	2zko	T49A	1.28	ProNAB
378	2zko	S42A	1.34	ProNAB
379	2zko	R37A	-0.03	ProNAB
380	2zi0	W50A	0.9	ProNAB
381	2zi0	P41A	1.38	ProNAB
382	2zi0	W50R	0.37	ProNAB
383	2y8w	H26A	0.19	ProNAB
384	2pjp	D511A	2.13	ProNAB
385	2pjp	W508A	4.21	ProNAB
386	2pjp	V509A	1.47	ProNAB
387	2pjp	R510A	3.75	ProNAB
388	2m8d	D139A	1.09	ProNAB
389	2m8d	K138A	1.5	ProNAB
390	2m8d	D136A	1.57	ProNAB
391	2m8d	Q135A	1.5	ProNAB
392	2m8d	W134F	1.47	ProNAB
393	2m8d	S133A	1.13	ProNAB
394	2ix1	F358A	0.23	ProNAB
395	2ix1	Y253A	0.93	ProNAB
396	2ix1	D230N	0.31	ProNAB
397	2ix1	D209N	-0.11	ProNAB
398	2ix1	D207N	0.4	ProNAB
399	2ix1	D201N	0.31	ProNAB
400	2c4r	F67A	0.74	ProNAB
401	2c4r	F57A	0.47	ProNAB
402	2c4r	D346N	0.77	ProNAB
403	2c4r	N305L	0.03	ProNAB
404	2c4r	R373A	-0.32	ProNAB
405	2i91	H187S	0.79	ProNAB
406	2i91	R184A	1.11	ProNAB
407	2i91	K136A	-0.06	ProNAB
408	1yvp	R120S	0.04	ProNAB
409	1yvp	H187S	1.86	ProNAB
410	1yvp	R184A	0.98	ProNAB
411	1yvp	K136A	-0.04	ProNAB
412	1urn	M51A	1.86	ProNAB
413	1urn	L49A	4.09	ProNAB
414	1urn	E19A	3.29	ProNAB
415	1u0b	N351A	1.86	ProNAB
416	1jbr	F51A	0.33	ProNAB
417	1jbr	T52A	0.89	ProNAB
418	1jbr	Q141A	0.44	ProNAB
419	1jbr	K69A	0.28	ProNAB
420	1jbr	K113A	0.76	ProNAB
421	1jbr	K111A	1.89	ProNAB
422	1jbr	K110A	1.5	ProNAB
423	1jbr	H49A	0.87	ProNAB
424	1jbr	D40A	0.22	ProNAB
425	1jbr	D143A	-0.54	ProNAB
426	1asy	K428A	0.82	ProNAB
427	1asy	F304A	0.0	ProNAB
428	1asy	Q300A	-0.11	ProNAB
429	1asy	S280A	0.0	ProNAB
430	1asy	T424A	0.8	ProNAB
431	1asy	T331A	1.09	ProNAB
432	1asy	T230A	1.38	ProNAB
433	1asy	S423A	-0.11	ProNAB
434	1asy	S329A	0.8	ProNAB
435	1asy	S301A	0.29	ProNAB
436	1asy	S181A	1.03	ProNAB
437	1asy	R119A	1.26	ProNAB
438	1asy	Q138A	1.39	ProNAB
439	1asy	Q121A	1.27	ProNAB
440	1asy	N328A	0.6	ProNAB
441	1asy	N227A	0.8	ProNAB
442	1asy	N117A	0.86	ProNAB
443	1asy	K553A	1.28	ProNAB
444	1asy	K180A	1.49	ProNAB
445	1asy	K155A	0.75	ProNAB
446	1asy	K142A	0.84	ProNAB
447	1asy	H334A	1.26	ProNAB
448	1asy	F127A	2.05	ProNAB
449	1asy	E327A	-0.24	ProNAB
450	1asy	E202A	0.98	ProNAB
451	1asy	E188A	1.52	ProNAB
452	1asy	D210A	1.38	ProNAB
453	2err	F158A	3.89	ProNAB
454	2err	F126W	1.6	ProNAB
455	2err	F126R	4.31	ProNAB
456	2err	F126L	3.46	ProNAB
457	2err	F126I	4.32	ProNAB
458	2err	F126H	1.88	ProNAB
459	2err	F160A	6.1	ProNAB
460	2err	H120A	3.0	ProNAB
461	2err	F126Y	0.42	ProNAB
462	2err	F126A	4.32	ProNAB
463	3j5s	Q8A	0.795	ProNAB
464	3j5s	K113Q	0.63	ProNAB
465	3j5s	M115G	0.73	ProNAB
466	3j5s	K136Q	0.07	ProNAB
467	3j5s	M143A	0.365	ProNAB
468	3j5s	R2Q	0.42	ProNAB
469	3j5s	R142Q	0.165	ProNAB
470	3j5s	K34Q	-0.02	ProNAB
471	1qfq	R7A	3.11	ProNAB
472	1qfq	R11K	2.43	ProNAB
473	1qfq	E9L	0.65	ProNAB
474	1gtf	T30V	2.265	ProNAB
475	1aud	F55W	0.62	ProNAB
476	1aud	F55Y	1.03	ProNAB
477	1urn	N15A	1.32	PremPRI
478	1urn	N16A	1.01	PremPRI
479	3k5q	H326A	3.35	PremPRI
480	3k5q	R364A	0.57	PremPRI
481	3ol6	K127A	0.5	PremPRI
482	4cio	E63K	1.08	PremPRI
483	4ngb	S1005A	0.09	PremPRI
484	4oog	P449A	1.08	PremPRI
485	4oog	R445A	1.08	PremPRI
486	4oog	R450A	1.08	PremPRI
487	4oog	S453K	1.05	PremPRI
488	1jbs	D143A	-0.52	pempni
489	1jbs	D40A	0.21	pempni
490	1jbs	F51A	0.32	pempni
491	1jbs	H49A	0.84	pempni
492	1jbs	K110A	1.44	pempni
493	1jbs	K113A	0.73	pempni
494	1jbs	K42A	0.27	pempni
495	1jbs	Q141A	0.42	pempni
496	1jbs	R65A	0.51	pempni
497	1jbs	T52A	0.85	pempni
498	1wne	K18A	0.39	pempni
499	1wne	K18E	0.2	pempni
500	1wne	K20A	1.73	pempni
501	1wne	K20E	0.32	pempni
502	1zdi	S52A	-0.33	pempni
503	2bx2	F57A	0.45	pempni
504	2bx2	F67A	0.71	pempni
505	2bx2	R373A	-0.3	pempni
506	2ix1	E390A	0.15	pempni
507	2ix1	E542A	-1.35	pempni
508	2ix1	R500A	0.27	pempni
509	2ix1	Y313A	0.51	pempni
510	2y8w	E24A	1.2	pempni
511	2y8w	E38A	0.39	pempni
512	2y8w	N102A	0.48	pempni
513	2y8w	R27A	-0.16	pempni
514	2y8w	S34A	0.02	pempni
515	2zzm	D223A	0.22	pempni
516	2zzm	K137A	0.52	pempni
517	2zzm	N265A	0.08	pempni
518	2zzm	P267A	0.08	pempni
519	2zzm	R145A	0.22	pempni
520	2zzm	R181A	0.15	pempni
521	2zzm	R186A	0.34	pempni
522	2zzm	Y177A	0.28	pempni
523	3k5q	H454A	1.18	pempni
524	3k5q	R288A	0.98	pempni
525	3ol6	K125A	1.16	pempni
526	3ol6	K126A	0.87	pempni
527	3ol6	K133A	0.59	pempni
528	3ol6	K314A	0.02	pempni
529	3ol6	R128A	1.11	pempni
530	3ol6	R188A	2.01	pempni
531	3ol6	Y118A	-0.04	pempni
532	3ol6	Y148A	0.17	pempni
533	3ol6	Y14A	0.07	pempni
534	3ol6	Y157A	0.39	pempni
535	4ngd	R927A	1.83	pempni
536	4ngd	S1005A	0.09	pempni
537	4ngd	W1014A	0.52	pempni
538	4ngd	Y961F	1.9	pempni
539	4ngd	Y966F	2.05	pempni
540	4oi0	D124A	1.62	pempni
541	4oi0	D235A	0.47	pempni
542	4oi0	P122A	0.31	pempni
543	4oi0	P122S	1.03	pempni
544	4oi0	R288K	0.52	pempni
545	4oi0	T230A	0.83	pempni
546	4oog	K392A	1.02	pempni
547	4oog	Q373A	0.21	pempni
548	4yvi	H180A	1.2	pempni
549	5elh	F149A	0.18	pempni
550	5elh	N143A	-0.06	pempni
551	5elk	R310A	1.6	pempni
552	5elk	Y216A	0.45	pempni
553	5en1	D49A	0.9	pempni
554	5en1	F24A	0.78	pempni
555	5en1	F66A	1.07	pempni
556	5en1	H108A	0.21	pempni
557	5ev1	Q147A	-0.32	pempni
558	5ev1	R227A	-0.33	pempni
559	5gxh	E197A	1.66	pempni
560	5gxh	F381A	2.16	pempni
561	5gxh	W14A	2.17	pempni
562	5gxh	Y15A	1.19	pempni
563	5gxh	Y474A	0.02	pempni
564	5www	R271A	0.86	pempni
565	5www	T268A	1.05	pempni
566	1c9s	D39A	0.8	mcsm
567	1c9s	E36A	-3.74	mcsm
568	1c9s	K37A	-3.03	mcsm
569	1c9s	K56A	-2.2	mcsm
570	1c9s	R58A	-2.0	mcsm
571	1c9s	R58K	-0.25	mcsm
572	1c9s	T30C	-1.3	mcsm
573	1c9s	T30D	-3.38	mcsm
574	1c9s	T30E	-3.62	mcsm
575	1c9s	T30I	-2.93	mcsm
576	1c9s	T30L	-3.15	mcsm
577	1c9s	T30P	-3.23	mcsm
578	1c9s	T30Q	-3.3	mcsm
579	1c9s	T30S	0.0	mcsm
580	1c9s	T30V	-2.696	mcsm
581	1qfq	R8H	-3.4	mcsm
582	1urn	F56A	-5.495	mcsm
583	1urn	F56H	-0.667	mcsm
584	1urn	F56L	-4.1	mcsm
585	1urn	F56Y	-1.267	mcsm
586	1urn	G53A	-2.9	mcsm
587	1urn	G53V	-5.7	mcsm
588	1urn	K50A	-1.25	mcsm
589	1urn	Q54A	-4.85	mcsm
590	1urn	Q54E	-6.6	mcsm
591	1urn	Q54N	-5.05	mcsm
592	1urn	T11V	-4.5	mcsm
593	1urn	Y13Q	-7.17	mcsm
594	1urn	Y13S	-6.6	mcsm
595	1urn	Y13T	-6.36	mcsm

Dataset used for testing the model.

S.No	PDB	Mutation	Experimental ΔΔG(kcal/mol)	Source
1	3rw6	A151E	-0.675	ProNAB
2	4pmw	A778Q	-0.12	ProNAB
3	2c4r	D305N	-0.21	ProNAB
4	6so9	V537I	0.35	ProNAB
5	5wlh	K1320A	0.13	ProNAB
6	2x1a	Y21F	0.0	ProNAB
7	1gtf	K40A	2.68	ProNAB
8	2leb	A76D	-1.68	ProNAB
9	6kwr	A44H	0.03	ProNAB
10	Izdi	A57K	-2.58	ProNAB
11	1si2	A273M	-0.37	ProNAB
12	1feu	A20R	-0.31	ProNAB
13	3am1	A22K	0.46	ProNAB
14	6d12	A472R	0.2	ProNAB
15	2c4r	D373R	0.03	ProNAB
16	4yvi	A59G	-1.74	ProNAB
17	3j5s	G54S	0.745	ProNAB
18	5ztm	K4A	1.77	ProNAB
19	1ytu	A163K	-0.79	ProNAB
20	1utd	M37K	-1.2	ProNAB
21	2c4r	D303N	0.11	ProNAB
22	2zzn	F177Y	-0.35	ProNAB
23	3zla	R56A	-1.67	ProNAB
24	4r8i	R24A	5.39	ProNAB
25	4r8i	K22V	0.03	ProNAB
26	6so9	R595M	0.97	ProNAB
27	1feu	A16S	-0.17	ProNAB
28	6cyt	W258A	1.52	ProNAB
29	3j5s	Y84A	0.275	ProNAB
30	1urn	F13Y	2.1	ProNAB
31	1urn	W56F	0.367	ProNAB
32	2la5	A11G	-0.26	ProNAB
33	2c4r	R373D	-0.03	ProNAB
34	5mpl	M186A	-0.025	ProNAB
35	5wwx	A365R	-1.24	ProNAB
36	4ngd	A926Y	-2.06	ProNAB
37	5ev1	P254V	0.44	ProNAB
38	1ttt	A53K	-0.08	ProNAB
39	4oi0	N124D	-0.96	ProNAB
40	1asy	A293K	-1.41	ProNAB
41	2kg0	F120A	2.82	ProNAB
42	5awh	K506A	4.17	ProNAB
43	4nha	A982H	-1.05	ProNAB
44	5eeu	K40M	0.47	ProNAB
45	4v4f	L38K	-1.7	ProNAB
46	1jbr	A65R	-0.53	ProNAB
47	1feu	N85H	-1.48	ProNAB
48	1c9s	N30T	2.7	ProNAB
49	3moj	A423G	-0.4	ProNAB
50	5w1h	A325W	0.75	ProNAB
51	1feu	H85T	1.48	ProNAB
52	4pmw	A275R	0.0	ProNAB
53	1ttt	A271E	-1.73	ProNAB
54	5m8i	A59K	-0.14	ProNAB
55	2e9t	K20A	1.8	ProNAB
56	1asy	A124T	-0.82	ProNAB
57	1ttt	K90A	0.65	ProNAB
58	5det	R38Q	0.88	ProNAB
59	3zla	R94A	-0.59	ProNAB
60	4yvi	A116E	-2.38	ProNAB
61	3ol6	A66K	0.08	ProNAB
62	1qfq	K4Q	-1.375	ProNAB
63	2mjh	A228P	-1.71	ProNAB
64	1zh5	A24Y	-2.53	ProNAB
65	3j5s	S54G	-0.745	ProNAB
66	3sn2	N685S	0.0	ProNAB
67	4qvd	Y25A	3.28	ProNAB
68	5elk	A316F	-1.69	ProNAB
69	1dfu	H88A	2.55	ProNAB
70	5dno	A331R	-0.87	ProNAB
71	4cio	E113G	-0.75	ProNAB
72	4v4f	A38K	-3.8	ProNAB
73	2i91	R120S	0.18	ProNAB
74	4yvi	W89P	-2.0	ProNAB
75	5eeu	M40K	-0.47	ProNAB
76	3vyx	A182K	-1.9	ProNAB
77	3sn2	R269A	1.21	ProNAB
78	4cio	M76R	0.41	ProNAB
79	1urn	A91S	2.2	ProNAB
80	2yh1	D215R	0.47	ProNAB
81	3k5q	A367Q	-1.57	ProNAB
82	2lec	A86R	-0.45	ProNAB
83	3j5s	K35Q	0.755	ProNAB
84	1jbs	A111K	-1.81	ProNAB
85	1feu	E87D	-2.04	ProNAB
86	4qei	G451V	1.41	ProNAB
87	6so9	A558Q	0.31	ProNAB
88	3wbm	A16K	-0.65	ProNAB
89	4ngb	W1014R	-0.38	ProNAB
90	5ztm	A171K	-1.82	ProNAB
91	3k5q	A325N	-1.01	ProNAB
92	4r3i	A475R	1.31	ProNAB
93	5ip2	R60A	0.05	ProNAB
94	1ttt	V350T	-1.61	ProNAB
95	5ho4	A24F	-0.81	ProNAB
96	4v4f	K38M	1.1	ProNAB
97	3j5s	G17F	-0.905	ProNAB
98	1gtf	A40K	-2.68	ProNAB
99	1aud	H55F	-0.45	ProNAB
100	4oi0	S123T	-0.29	ProNAB
101	Izdi	A53S	0.35	ProNAB
102	2kg0	A150K	-0.1	ProNAB
103	3k49	A866S	0.0	ProNAB
104	4cio	A45H	0.61	ProNAB
105	5ip2	A60R	-0.05	ProNAB
106	5h1k	F383Y	-1.64	ProNAB
107	3k5y	A554S	0.02	ProNAB
108	5ho4	A115F	-1.13	ProNAB
109	Izdi	K61A	2.53	ProNAB
110	4tuw	T230E	-0.6	ProNAB
111	5mpg	A92R	-0.68	ProNAB
112	3wbm	E60F	-0.41	ProNAB
113	1qfq	N2D	-1.28	ProNAB
114	4yvi	A134G	-2.32	ProNAB
115	2kxn	A199P	-0.73	ProNAB