Protein Bioinformatics Lab

S.No Title Role Funding Agency Duration Funding (Rs. in lakhs)
1. Controlling Papaya Ring Spot Virus transmission by interfering Protein-Protein Interactions through biogenic nano-porous silica formulations: Systematic Modeling and Molecular Dynamics Investigations. NNP-TNAU, Coimbatore. PI Department of Biotechnology, Govt.of India. 2024-2027 18.21
2. Accelerating identification of RNA-targeted therapeutics to mitigate breast cancer through development of computational methods. PI Indian Council of Medical Research, Govt. of India. 2025-2028 65.89
3. Identification of Potent Drug for Life-Threatening Diseases. NNP-Alagappa University, Karaikudi. PI Department of Biotechnology, Govt.of India. 2023-2028 24.22
4. Genome informatics networks to understand plant stress management. NNP-NCBS, Bengaluru. PI Department of Biotechnology, Govt.of India. 2023-2028 55.68
5. Development of a comprehensive database for disease causing mutations and tool for predicting the binding affinity of protein carbohydrate complexes: influence of binding affinity on disease causing mutations PI Department of Biotechnology, Govt.of India. 2024-2027 37.48
6. Explore Viral Involvement in the Alzheimer’s Amyloid Beta Peptides Toxicity: Multiscale In-Silico Experimental Approach PI Science and Engineering Research Board (SERB), Govt. of India. 2024-2026 29.80
S.No Title Role Funding Agency Duration Funding (Rs. in Lakhs)
1. A Method to improve Modelling of Protein-protein Complexes using AlphaFold2 and Filtered Coevolutionary Signals. PI Department of Biotechnology, Govt.of India. 2021-2024 14.98
2. An Integrative Approach for Understanding the Structure, Function and Dynamics of HIV Protease: Applications to Design Novel Inhibitors PI Department of Science and Technology, Govt. of India. 2021-2024 34.55
3. Efficacy of HSP90 mitochondrial targeting of Withanolide A & Withaferin A in Hepatocellular carcinoma PI Science and Engineering Research Board (SERB), Govt. of India. 2020-2024 18.2
4. Integrated approach for understanding the binding affinity of protein-nucleic acid complexes: development of database, tools and applications to diseases PI Science and Engineering Research Board (SERB), Govt. of India. 2020-2023 38.47
5. Structure based drug design and mechanistic studies for COVID19 PI Science and Engineering Research Board (SERB), Govt. of India. 2020-2023 18.2
6. Adapting the standard SIR model for COVID-19 and effects of climate and lockdowns on infectious spread of SARS-CoV-2 PI Science and Engineering Research Board (SERB), Govt. of India. 2020-2021 5.5
7. Identification of therapeutic targets for Glioblastoma by Single-Cell RNA-Seq Analysis. PI Department of Health Research, Govt. of India. 2020-2022 42
8. Elucidation of mechanism of Drug resistance associated with Breast Cancer and Ovarian Cancer through network biology approach. PI Science and Engineering Research Board (SERB), Govt. of India. 2019-2022 18
9. Predictive modeling of nucleic acid recognition dynamics and structured complex formation by disordered proteins PI Council of Scientific and Industrial Research, Govt. of India. 2019-2021 17
10. Tackling COVID-19: Repurposing of therapeutic antibodies and development of a comprehensive antibody database PI Robert Bosch Centre for Data Science and Artificial Intelligence, IIT Madras 2020-2021 11.42
11. A computational pipeline for understanding disease-causing mutations in Genomes Algorithms for context analysis and Development of Prediction Tools: Development of computational tools for analysis and prediction of disease-causing mutations PI Department of Biotechnology, Govt. of India. 2017-2020 38
12. Structural and molecular approach of targeting Bcl-2 family anti-apoptotic proteins PI Department of Biotechnology, Govt. of India. 2017-2020 41