MPA-MutPred: Membrane Protein complex Mutation Affinity Predictor

Dataset

S.No. PDB ID Protein Complex Type Functional Class  Chain Mutation Experimental ΔΔG (kcal/mol)
1 1A22 MP-MP Receptor B R243A 0.28
2 1A22 MP-MP Receptor B E244A 0.65
3 1A22 MP-MP Receptor B R270A 0.42
4 1A22 MP-MP Receptor B R271A 0.60
5 1A22 MP-MP Receptor B T273A -0.44
6 1A22 MP-MP Receptor B Q274A -0.58
7 1A22 MP-MP Receptor B E275A -0.08
8 1A22 MP-MP Receptor B W276A 0.56
9 1A22 MP-MP Receptor B W280A 0.17
10 1A22 MP-MP Receptor B S298A -0.33
11 1A22 MP-MP Receptor B S299A -0.51
12 1A22 MP-MP Receptor B T301A 1.09
13 1A22 MP-MP Receptor B S302A 0.47
14 1A22 MP-MP Receptor B I303A 0.43
15 1A22 MP-MP Receptor B W304F 2.78
16 1A22 MP-MP Receptor B I305A 0.13
17 1A22 MP-MP Receptor B P306A 2.63
18 1A22 MP-MP Receptor B D326A 0.98
19 1A22 MP-MP Receptor B E327A 0.41
20 1A22 MP-MP Receptor B R417A 0.33
21 1DAN MP-MP Enzyme T  W14F 0.69
22 1DAN MP-MP Enzyme T  T17A 0.12
23 1DAN MP-MP Enzyme T  N18A 0.18
24 1DAN MP-MP Enzyme T  K20A 2.59
25 1DAN MP-MP Enzyme T  K20R 1.68
26 1DAN MP-MP Enzyme T  T21A -0.16
27 1DAN MP-MP Enzyme T  I22A 0.64
28 1DAN MP-MP Enzyme T  E24A 0.66
29 1DAN MP-MP Enzyme T  Q37A 0.55
30 1DAN MP-MP Enzyme T  K41A 0.32
31 1DAN MP-MP Enzyme T  S42A -0.07
32 1DAN MP-MP Enzyme T  D44A 0.73
33 1DAN MP-MP Enzyme T  W45F 1.27
34 1DAN MP-MP Enzyme T  K46A 0.23
35 1DAN MP-MP Enzyme T  S47A 0.04
36 1DAN MP-MP Enzyme T  K48A 0.41
37 1DAN MP-MP Enzyme T  F50A 0.44
38 1DAN MP-MP Enzyme T  D58A 1.99
39 1DAN MP-MP Enzyme T  D58E 1.38
40 1DAN MP-MP Enzyme U Y94A 1.02
41 1DAN MP-MP Enzyme U E99A -0.18
42 1DAN MP-MP Enzyme U E128A 0.09
43 1DAN MP-MP Enzyme U L133A -0.03
44 1DAN MP-MP Enzyme U R135A 0.52
45 1DAN MP-MP Enzyme U F140A 1.28
46 1DAN MP-MP Enzyme U W158F 0.12
47 1DAN MP-MP Enzyme U S163A 0.02
48 1DAN MP-MP Enzyme U G164R -0.16
49 1DAN MP-MP Enzyme U T203A 0.14
50 1DAN MP-MP Enzyme U E208A 0.00
51 1DE4 MP-MP Transporter C V622A 0.08
52 1DE4 MP-MP Transporter C R623A 0.94
53 1DE4 MP-MP Transporter C Q640A 1.43
54 1DE4 MP-MP Transporter C W641A 0.81
55 1DE4 MP-MP Transporter C S644A 0.10
56 1DE4 MP-MP Transporter C F650A 1.56
57 1DE4 MP-MP Transporter C R651A 0.02
58 1DE4 MP-MP Transporter C S654A -0.15
59 1DE4 MP-MP Transporter C T658A 0.30
60 1DE4 MP-MP Transporter C N662A 0.50
61 1IAR MP-MP Transporter B F41A 2.26
62 1IAR MP-MP Transporter B L42A 0.00
63 1IAR MP-MP Transporter B L43A 0.33
64 1IAR MP-MP Transporter B D66A 0.72
65 1IAR MP-MP Transporter B D67A 2.35
66 1IAR MP-MP Transporter B V68A 0.84
67 1IAR MP-MP Transporter B S70A -0.24
68 1IAR MP-MP Transporter B S93A -0.18
69 1IAR MP-MP Transporter B D125A 0.80
70 1IAR MP-MP Transporter B N126A 0.68
71 1IAR MP-MP Transporter B Y127A 2.16
72 1IAR MP-MP Transporter B Y127F -0.18
73 1KAC MP-MP Miscellaneous B Y82A 1.32
74 1KAC MP-MP Miscellaneous B Y85K 1.44
75 1KTZ MP-MP Enzyme B L27A 1.82
76 1KTZ MP-MP Enzyme B F30A 2.98
77 1KTZ MP-MP Enzyme B D32A 1.52
78 1KTZ MP-MP Enzyme B D32N 2.00
79 1KTZ MP-MP Enzyme B S49A 0.33
80 1KTZ MP-MP Enzyme B I50A 1.90
81 1KTZ MP-MP Enzyme B T51A 1.51
82 1KTZ MP-MP Enzyme B S52A 0.22
83 1KTZ MP-MP Enzyme B S52L 4.04
84 1KTZ MP-MP Enzyme B I53A 1.37
85 1KTZ MP-MP Enzyme B E55A 1.22
86 1KTZ MP-MP Enzyme B V77A 0.41
87 1KTZ MP-MP Enzyme B D118A 0.81
88 1KTZ MP-MP Enzyme B E119A 1.49
89 1KTZ MP-MP Enzyme B E119Q 1.63
90 1REW MP-MP Receptor C Q86A 2.66
91 2AJF MP-MP Transporter A D38A 0.65
92 2AJF MP-MP Transporter A Y41A 1.45
93 2AJF MP-MP Transporter A Y41F 1.40
94 2AW2 MP-MP Receptor B P17A 2.57
95 2AW2 MP-MP Receptor B Y23A 1.88
96 2AW2 MP-MP Receptor B V36A 1.10
97 2HLE MP-MP Transporter A L95R 2.29
98 2HLE MP-MP Transporter A K149Q -0.41
99 2REX MP-MP Miscellaneous A L1815Y 0.56
100 3BN9 MP-MP Transporter D T28R 0.33
101 3BN9 MP-MP Transporter D S30G 1.19
102 3BN9 MP-MP Transporter D S30N 1.15
103 3BN9 MP-MP Transporter D T98Q -0.02
104 3BN9 MP-MP Transporter D T98R -0.06
105 3BN9 MP-MP Transporter D Y99S 0.46
106 3BP8 MP-MP Miscellaneous C  A63F 0.62
107 3F7P MP-MP Miscellaneous C R1281K 2.21
108 3ONA MP-MP Receptor B K18A 1.64
109 3ONA MP-MP Receptor B I19A 0.20
110 3ONA MP-MP Receptor B L23A 1.12
111 3ONA MP-MP Receptor B F49A 1.08
112 4JRA MP-MP Transporter C N559A -0.11
113 4K71 MP-MP Miscellaneous B H161A 0.64
114 4K71 MP-MP Miscellaneous B H161F 0.18
115 4WW2 MP-MP Miscellaneous A Y31F -0.44
116 4WW2 MP-MP Miscellaneous B Y55F 0.65
117 4WW2 MP-MP Miscellaneous B Q57A 0.86
118 4WW2 MP-MP Miscellaneous B R109A 0.65
119 5IXD MP-MP Enzyme B W257A 0.74
120 5IXD MP-MP Enzyme B R260A 0.13
121 5IXD MP-MP Enzyme B K262A 0.66
122 5WT9 MP-MP Miscellaneous G N49A 0.26
123 5WT9 MP-MP Miscellaneous G N116A 0.07
124 5XXY MP-MP Miscellaneous A I54A 0.70
125 5XXY MP-MP Miscellaneous A Y56A 0.59
126 5XXY MP-MP Miscellaneous A E58A 1.72
127 5XXY MP-MP Miscellaneous A D61A 0.00
128 5XXY MP-MP Miscellaneous A N63A 0.33
129 5XXY MP-MP Miscellaneous A R113A 1.27
130 5XXY MP-MP Miscellaneous A M115A 0.90
131 5XXY MP-MP Miscellaneous A Y123A 0.91
132 5XXY MP-MP Miscellaneous A R125A 1.05
133 6AAF MP-MP Miscellaneous B L386A 1.50
134 6AAF MP-MP Miscellaneous B D391A 1.16
135 6AAF MP-MP Miscellaneous B E393A 0.05
136 6AAF MP-MP Miscellaneous B E395A 0.39
137 6AAF MP-MP Miscellaneous B L397A 1.09
138 6ARQ MP-MP Receptor A Y75F -0.19
139 6ARQ MP-MP Receptor A Y123F 0.29
140 6MKZ MP-MP Receptor B R38A 0.99
141 6MKZ MP-MP Receptor B S50A 0.24
142 6MKZ MP-MP Receptor B N60A 0.40
143 3S9D MP-MP Receptor B T44A 1.67
144 3S9D MP-MP Receptor B I45A 1.77
145 3S9D MP-MP Receptor B M46A 2.32
146 3S9D MP-MP Receptor B M46V 1.82
147 3S9D MP-MP Receptor B S47A 0.54
148 3S9D MP-MP Receptor B K48A 0.69
149 3S9D MP-MP Receptor B E50R 0.65
150 3S9D MP-MP Receptor B E50A 0.21
151 3S9D MP-MP Receptor B D51A 0.00
152 3S9D MP-MP Receptor B T75A 0.26
153 3S9D MP-MP Receptor B H76A 0.64
154 3S9D MP-MP Receptor B E77A 2.41
155 3S9D MP-MP Receptor B A78M -0.17
156 3S9D MP-MP Receptor B V80A 2.32
157 3S9D MP-MP Receptor B N98A -0.13
158 3S9D MP-MP Receptor B W100A 1.05
159 3S9D MP-MP Receptor B I103A 1.50
160 3S9D MP-MP Receptor B H187A 0.00
161 6ATK MP-MP Enzyme A D288A 1.40
162 6ATK MP-MP Enzyme A Y289A 1.72
163 6ATK MP-MP Enzyme A I309A 1.90
164 6ATK MP-MP Enzyme D F318A 1.54
165 4IOP MP-MP Receptor A H155A 0.68
166 3ALZ MP-MP Miscellaneous B N72S 0.67
167 3ALZ MP-MP Miscellaneous B V74A 0.80
168 3ALZ MP-MP Miscellaneous B E75S 1.60
169 3ALZ MP-MP Miscellaneous B K77S 0.70
170 1A22 MP-MP Receptor B A243R -0.28
171 1A22 MP-MP Receptor B A244E -0.65
172 1A22 MP-MP Receptor B A270R -0.42
173 1A22 MP-MP Receptor B A271R -0.60
174 1A22 MP-MP Receptor B A273T 0.44
175 1A22 MP-MP Receptor B A274Q 0.58
176 1A22 MP-MP Receptor B A275E 0.08
177 1A22 MP-MP Receptor B A276W -0.56
178 1A22 MP-MP Receptor B A280W -0.17
179 1A22 MP-MP Receptor B A298S 0.33
180 1A22 MP-MP Receptor B A299S 0.51
181 1A22 MP-MP Receptor B A301T -1.09
182 1A22 MP-MP Receptor B A302S -0.47
183 1A22 MP-MP Receptor B A303I -0.43
184 1A22 MP-MP Receptor B F304W -2.78
185 1A22 MP-MP Receptor B A305I -0.13
186 1A22 MP-MP Receptor B A306P -2.63
187 1A22 MP-MP Receptor B A326D -0.98
188 1A22 MP-MP Receptor B A327E -0.41
189 1A22 MP-MP Receptor B A417R -0.33
190 1DAN MP-MP Enzyme T  F14W -0.69
191 1DAN MP-MP Enzyme T  A17T -0.12
192 1DAN MP-MP Enzyme T  A18N -0.18
193 1DAN MP-MP Enzyme T  A20K -2.59
194 1DAN MP-MP Enzyme T  R20K -1.68
195 1DAN MP-MP Enzyme T  A21T 0.16
196 1DAN MP-MP Enzyme T  A22I -0.64
197 1DAN MP-MP Enzyme T  A24E -0.66
198 1DAN MP-MP Enzyme T  A37Q -0.55
199 1DAN MP-MP Enzyme T  A41K -0.32
200 1DAN MP-MP Enzyme T  A42S 0.07
201 1DAN MP-MP Enzyme T  A44D -0.73
202 1DAN MP-MP Enzyme T  F45W -1.27
203 1DAN MP-MP Enzyme T  A46K -0.23
204 1DAN MP-MP Enzyme T  A47S -0.04
205 1DAN MP-MP Enzyme T  A48K -0.41
206 1DAN MP-MP Enzyme T  A50F -0.44
207 1DAN MP-MP Enzyme T  A58D -1.99
208 1DAN MP-MP Enzyme T  E58D -1.38
209 1DAN MP-MP Enzyme U A94Y -1.02
210 1DAN MP-MP Enzyme U A99E 0.18
211 1DAN MP-MP Enzyme U A128E -0.09
212 1DAN MP-MP Enzyme U A133L 0.03
213 1DAN MP-MP Enzyme U A135R -0.52
214 1DAN MP-MP Enzyme U A140F -1.28
215 1DAN MP-MP Enzyme U F158W -0.12
216 1DAN MP-MP Enzyme U A163S -0.02
217 1DAN MP-MP Enzyme U R164G 0.16
218 1DAN MP-MP Enzyme U A203T -0.14
219 1DAN MP-MP Enzyme U A207V 0.19
220 1DAN MP-MP Enzyme U A208E 0.00
221 1DE4 MP-MP Transporter C A622V -0.08
222 1DE4 MP-MP Transporter C A623R -0.94
223 1DE4 MP-MP Transporter C A640Q -1.43
224 1DE4 MP-MP Transporter C A641W -0.81
225 1DE4 MP-MP Transporter C A644S -0.10
226 1DE4 MP-MP Transporter C A650F -1.56
227 1DE4 MP-MP Transporter C A651R -0.02
228 1DE4 MP-MP Transporter C A654S 0.15
229 1DE4 MP-MP Transporter C A658T -0.30
230 1DE4 MP-MP Transporter C A662N -0.50
231 1IAR MP-MP Transporter B A41F -2.26
232 1IAR MP-MP Transporter B A42L 0.00
233 1IAR MP-MP Transporter B A43L -0.33
234 1IAR MP-MP Transporter B A66D -0.72
235 1IAR MP-MP Transporter B A68V -0.84
236 1IAR MP-MP Transporter B A70S 0.24
237 1IAR MP-MP Transporter B A93S 0.18
238 1IAR MP-MP Transporter B A125D -0.80
239 1IAR MP-MP Transporter B A126N -0.68
240 1IAR MP-MP Transporter B A127Y -2.16
241 1IAR MP-MP Transporter B F127Y 0.18
242 1KAC MP-MP Miscellaneous B A82Y -1.32
243 1KTZ MP-MP Enzyme B A27L -1.82
244 1KTZ MP-MP Enzyme B A30F -2.98
245 1KTZ MP-MP Enzyme B A32D -1.52
246 1KTZ MP-MP Enzyme B N32D -2.00
247 1KTZ MP-MP Enzyme B A49S -0.33
248 1KTZ MP-MP Enzyme B A50I -1.90
249 1KTZ MP-MP Enzyme B A51T -1.51
250 1KTZ MP-MP Enzyme B A52S -0.22
251 1KTZ MP-MP Enzyme B L52S -4.04
252 1KTZ MP-MP Enzyme B A53I -1.37
253 1KTZ MP-MP Enzyme B A55E -1.22
254 1KTZ MP-MP Enzyme B A77V -0.41
255 1KTZ MP-MP Enzyme B A118D -0.81
256 1KTZ MP-MP Enzyme B A119E -1.49
257 1KTZ MP-MP Enzyme B Q119E -1.63
258 1REW MP-MP Receptor C A86Q -2.66
259 2AJF MP-MP Transporter A A38D -0.65
260 2AJF MP-MP Transporter A A41Y -1.45
261 2AJF MP-MP Transporter A F41Y -1.40
262 2AW2 MP-MP Receptor B A17P -2.57
263 2AW2 MP-MP Receptor B A23Y -1.88
264 2AW2 MP-MP Receptor B A36V -1.10
265 2HLE MP-MP Transporter A R95L -2.29
266 2HLE MP-MP Transporter A Q149K 0.41
267 2REX MP-MP Miscellaneous A Y1815L -0.56
268 2Y8T MP-MP Miscellaneous A A230Y -1.38
269 3BN9 MP-MP Transporter D R28T -0.33
270 3BN9 MP-MP Transporter D G30S -1.19
271 3BN9 MP-MP Transporter D N30S -1.15
272 3BN9 MP-MP Transporter D Q98T 0.02
273 3BN9 MP-MP Transporter D R98T 0.06
274 3BN9 MP-MP Transporter D S99Y -0.46
275 3BP8 MP-MP Miscellaneous C F63 A -0.62
276 3ONA MP-MP Receptor B A19I -0.20
277 3ONA MP-MP Receptor B A23L -1.12
278 3ONA MP-MP Receptor B A44R -1.88
279 3ONA MP-MP Receptor B A49F -1.08
280 4JRA MP-MP Transporter C A559N 0.11
281 4K71 MP-MP Miscellaneous B A161H -0.64
282 4K71 MP-MP Miscellaneous B F161H -0.18
283 4WW2 MP-MP Miscellaneous A F31Y 0.44
284 4WW2 MP-MP Miscellaneous B A55Y -0.65
285 4WW2 MP-MP Miscellaneous B A57Q -0.65
286 5IXD MP-MP Enzyme B A257W -0.74
287 5IXD MP-MP Enzyme B A262K -0.66
288 5IXD MP-MP Enzyme B A265R -0.49
289 5WT9 MP-MP Miscellaneous G A49N -0.26
290 5WT9 MP-MP Miscellaneous G A116N -0.07
291 5XXY MP-MP Miscellaneous A A54I -0.70
292 5XXY MP-MP Miscellaneous A A56Y -0.59
293 5XXY MP-MP Miscellaneous A A63N -0.33
294 5XXY MP-MP Miscellaneous A A115M -0.90
295 5XXY MP-MP Miscellaneous A A123Y -0.91
296 5XXY MP-MP Miscellaneous A A125R -1.05
297 6AAF MP-MP Miscellaneous B A388F -0.89
298 6AAF MP-MP Miscellaneous B A395E -0.39
299 6AAF MP-MP Miscellaneous B A397L -1.09
300 6ARQ MP-MP Receptor A A67L -0.05
301 6ARQ MP-MP Receptor A A72H 0.30
302 6ARQ MP-MP Receptor A F75Y 0.19
303 6ARQ MP-MP Receptor A A78Y 0.06
304 6ARQ MP-MP Receptor A F123Y -0.29
305 6MKZ MP-MP Receptor B A38R -0.99
306 6MKZ MP-MP Receptor B A50S -0.24
307 6MKZ MP-MP Receptor B A60N -0.40
308 6MKZ MP-MP Receptor B A70Y 0.00
309 3S9D MP-MP Receptor B A44T -1.67
310 3S9D MP-MP Receptor B A45I -1.77
311 3S9D MP-MP Receptor B A46M -2.32
312 3S9D MP-MP Receptor B V46M -1.82
313 3S9D MP-MP Receptor B A47S -0.54
314 3S9D MP-MP Receptor B A48K -0.69
315 3S9D MP-MP Receptor B R50E -0.65
316 3S9D MP-MP Receptor B A50E -0.21
317 3S9D MP-MP Receptor B A51D 0.00
318 3S9D MP-MP Receptor B A75T -0.26
319 3S9D MP-MP Receptor B A76H -0.64
320 3S9D MP-MP Receptor B A77E -2.41
321 3S9D MP-MP Receptor B M78A 0.17
322 3S9D MP-MP Receptor B A80V -2.32
323 3S9D MP-MP Receptor B A98N 0.13
324 3S9D MP-MP Receptor B A100W -1.05
325 3S9D MP-MP Receptor B A103I -1.50
326 3S9D MP-MP Receptor B A187H 0.00
327 6ATK MP-MP Enzyme A A288D -1.40
328 6ATK MP-MP Enzyme A A289Y -1.72
329 6ATK MP-MP Enzyme A A318L -1.48
330 6ATK MP-MP Enzyme D A318F -1.54
331 4IOP MP-MP Receptor A A155H -0.68
332 4IOP MP-MP Receptor A A152D 0.19
333 3ALZ MP-MP Miscellaneous B A74V -0.80
334 3ALZ MP-MP Miscellaneous B S77K -0.70
335 1IAR MP-MP Transporter B A39L -3.01
336 1IAR MP-MP Transporter B F183Y -3.40
337 1DE4 MP-MP Transporter C F650Q 2.51
338 1IAR MP-MP Transporter B A72D -4.34
339 1IAR MP-MP Transporter B A13Y -5.22
340 1IAR MP-MP Transporter B V69A 2.10
341 4WW2 MP-MP Miscellaneous B A109R -2.32
342 4WW2 MP-MP Miscellaneous A Q112A 2.32
343 1IAR MP-MP Transporter B A183Y -3.92
344 1DE4 MP-MP Transporter C R629A 2.37
345 1A22 MP-GP Receptor A C182A 1.02
346 1A22 MP-GP Receptor A D171A 1.16
347 1A22 MP-GP Receptor A D26E -0.13
348 1A22 MP-GP Receptor A E174A -0.90
349 1A22 MP-GP Receptor A E186A -0.14
350 1A22 MP-GP Receptor A E56A 0.84
351 1A22 MP-GP Receptor A E65A -0.31
352 1A22 MP-GP Receptor A E66A 0.44
353 1A22 MP-GP Receptor A F176A 1.64
354 1A22 MP-GP Receptor A F176Y 1.27
355 1A22 MP-GP Receptor A F191A 0.19
356 1A22 MP-GP Receptor A F25A -0.27
357 1A22 MP-GP Receptor A H18A -0.21
358 1A22 MP-GP Receptor A H21A -0.66
359 1A22 MP-GP Receptor A I179A 0.59
360 1A22 MP-GP Receptor A I179M 0.59
361 1A22 MP-GP Receptor A K168A 0.05
362 1A22 MP-GP Receptor A K172A 1.54
363 1A22 MP-GP Receptor A N63A 0.71
364 1A22 MP-GP Receptor A Q68A 0.99
365 1A22 MP-GP Receptor A R167A -0.16
366 1A22 MP-GP Receptor A R178A 2.41
367 1A22 MP-GP Receptor A R178K 0.95
368 1A22 MP-GP Receptor A R178N 1.27
369 1A22 MP-GP Receptor A R183A 0.44
370 1A22 MP-GP Receptor A R64A 1.80
371 1A22 MP-GP Receptor A R64K -0.31
372 1A22 MP-GP Receptor A S62A 0.61
373 1A22 MP-GP Receptor A T175S 1.69
374 1A22 MP-GP Receptor A Y164A 0.76
375 1BP3 MP-GP Receptor A H18A 0.19
376 1BP3 MP-GP Receptor A H21A -0.18
377 1BP3 MP-GP Receptor A F25A 1.15
378 1BP3 MP-GP Receptor A S62A 1.41
379 1BP3 MP-GP Receptor A N63A 0.86
380 1BP3 MP-GP Receptor A R64A 0.35
381 1BP3 MP-GP Receptor A E65A 0.55
382 1BP3 MP-GP Receptor A Q68A 0.11
383 1BP3 MP-GP Receptor A Y164A 0.45
384 1BP3 MP-GP Receptor A R167A 2.12
385 1BP3 MP-GP Receptor A K168A 1.73
386 1BP3 MP-GP Receptor A D171A 0.07
387 1BP3 MP-GP Receptor A K172A 2.02
388 1BP3 MP-GP Receptor A E174A 0.17
389 1BP3 MP-GP Receptor A T175S 0.49
390 1BP3 MP-GP Receptor A F176A 1.94
391 1BP3 MP-GP Receptor A R178A 1.15
392 1BP3 MP-GP Receptor A I179A 0.35
393 1BP3 MP-GP Receptor A I179M -0.16
394 1BP3 MP-GP Receptor A R183A 0.57
395 1BP3 MP-GP Receptor A S188A -0.30
396 1F47 MP-GP Enzyme A D4A 0.69
397 1F47 MP-GP Enzyme A Y5A 0.87
398 1F47 MP-GP Enzyme A L6A 0.92
399 1F47 MP-GP Enzyme A D7A 1.73
400 1F47 MP-GP Enzyme A D7G 1.14
401 1F47 MP-GP Enzyme A D7S 2.06
402 1F47 MP-GP Enzyme A I8A 2.51
403 1F47 MP-GP Enzyme A P9A -0.06
404 1F47 MP-GP Enzyme A F11A 2.44
405 1F47 MP-GP Enzyme A L12A 2.29
406 1F47 MP-GP Enzyme A K14A -0.04
407 1F47 MP-GP Enzyme A Q15A -0.05
408 1FSS MP-GP Enzyme B T8V 0.37
409 1FSS MP-GP Enzyme B T9I -0.23
410 1FSS MP-GP Enzyme B T9N 1.20
411 1FSS MP-GP Enzyme B R11K 0.32
412 1FSS MP-GP Enzyme B A12S 0.32
413 1FSS MP-GP Enzyme B R27F 2.43
414 1FSS MP-GP Enzyme B R27M 2.66
415 1FSS MP-GP Enzyme B R27Y 2.63
416 1FSS MP-GP Enzyme B H29K -0.62
417 1FSS MP-GP Enzyme B H29R -1.49
418 1FSS MP-GP Enzyme B K32R 1.08
419 1FSS MP-GP Enzyme B M33F 0.94
420 1FSS MP-GP Enzyme B M33L 0.96
421 1FSS MP-GP Enzyme B M33Q 1.57
422 1FSS MP-GP Enzyme B M33Y 1.39
423 1FSS MP-GP Enzyme B V34T 1.59
424 1FSS MP-GP Enzyme B L35W 1.45
425 1FSS MP-GP Enzyme B N47F 0.49
426 1FSS MP-GP Enzyme B N47R -0.53
427 1FSS MP-GP Enzyme B N47W 0.12
428 1IAR MP-GP Transporter A I5A 1.17
429 1IAR MP-GP Transporter A I5R 0.80
430 1IAR MP-GP Transporter A T6A -0.10
431 1IAR MP-GP Transporter A T6D 1.39
432 1IAR MP-GP Transporter A Q8A -0.02
433 1IAR MP-GP Transporter A Q8R 0.04
434 1IAR MP-GP Transporter A E9Q 3.11
435 1IAR MP-GP Transporter A K12E 0.14
436 1IAR MP-GP Transporter A K12S -0.01
437 1IAR MP-GP Transporter A T13A 0.98
438 1IAR MP-GP Transporter A T13D -0.22
439 1IAR MP-GP Transporter A R53A 1.71
440 1IAR MP-GP Transporter A R53Q 0.84
441 1IAR MP-GP Transporter A Y56A 0.93
442 1IAR MP-GP Transporter A Q78A 0.12
443 1IAR MP-GP Transporter A Q78E 0.24
444 1IAR MP-GP Transporter A R81A 0.48
445 1IAR MP-GP Transporter A R81E 1.46
446 1IAR MP-GP Transporter A F82A -0.09
447 1IAR MP-GP Transporter A F82D -0.58
448 1IAR MP-GP Transporter A K84A 0.34
449 1IAR MP-GP Transporter A K84D 1.88
450 1IAR MP-GP Transporter A R85A 0.43
451 1IAR MP-GP Transporter A R85E 1.22
452 1IAR MP-GP Transporter A R88A 3.75
453 1IAR MP-GP Transporter A R88Q 2.83
454 1IAR MP-GP Transporter A N89A 1.56
455 1IAR MP-GP Transporter A W91A 0.73
456 1IAR MP-GP Transporter A W91D 1.31
457 1KTZ MP-GP Enzyme A R25A 1.48
458 1KTZ MP-GP Enzyme A R25K 1.15
459 1KTZ MP-GP Enzyme A R94A 2.88
460 1KTZ MP-GP Enzyme A R94K 2.20
461 1KTZ MP-GP Enzyme A V92I 0.24
462 1P6A MP-GP Miscellaneous A S489Y -1.25
463 2AJF MP-GP Transporter E N479K 2.01
464 2AJF MP-GP Transporter E T487S 1.82
465 2J1K MP-GP Miscellaneous C G370D 0.18
466 2J1K MP-GP Miscellaneous C R384A 0.76
467 2REX MP-GP Miscellaneous B Y114F 0.00
468 3BP8 MP-GP Miscellaneous A F136A 0.71
469 3BPO MP-GP Receptor A R11A 0.26
470 3BPO MP-GP Receptor A E15A -0.04
471 3BPO MP-GP Receptor A D87A 0.29
472 3BPO MP-GP Receptor A T88A 0.02
473 3BPO MP-GP Receptor A K89A 1.20
474 3BPO MP-GP Receptor A I90A 1.37
475 3BPO MP-GP Receptor A E91A 1.23
476 3MZG MP-GP Receptor A H138A 0.06
477 3MZG MP-GP Receptor A H173A 1.21
478 3MZG MP-GP Receptor A H195A 0.37
479 3N06 MP-GP Receptor A H27A 0.12
480 3N0P MP-GP Receptor A H30A 0.36
481 3NCB MP-GP Receptor A H180A 1.63
482 3Q3J MP-GP Miscellaneous B Y114F 0.21
483 3S9D MP-GP Receptor A L15A 1.28
484 3S9D MP-GP Receptor A L15A 1.96
485 3S9D MP-GP Receptor A M16A 0.12
486 3S9D MP-GP Receptor A R22A 0.17
487 3S9D MP-GP Receptor A I24A -0.13
488 3S9D MP-GP Receptor A S25A -0.08
489 3S9D MP-GP Receptor A S25A -0.21
490 3S9D MP-GP Receptor A L26A 1.01
491 3S9D MP-GP Receptor A L26A 1.02
492 3S9D MP-GP Receptor A L26A 1.49
493 3S9D MP-GP Receptor A F27A 0.52
494 3S9D MP-GP Receptor A F27A 0.90
495 3S9D MP-GP Receptor A L30V 2.64
496 3S9D MP-GP Receptor A L30A 3.75
497 3S9D MP-GP Receptor A L30A 3.86
498 3S9D MP-GP Receptor A R33Q 6.08
499 3S9D MP-GP Receptor A R33K 4.67
500 3S9D MP-GP Receptor A R33A 5.42
501 3S9D MP-GP Receptor A H34A 0.41
502 3S9D MP-GP Receptor A H34A 0.57
503 3S9D MP-GP Receptor A D35A 0.24
504 3S9D MP-GP Receptor A D35A 0.25
505 3S9D MP-GP Receptor A T79A 0.17
506 3S9D MP-GP Receptor A L80A 0.30
507 3S9D MP-GP Receptor A E96A 0.17
508 3S9D MP-GP Receptor A R144A 2.18
509 3S9D MP-GP Receptor A R144A 2.18
510 3S9D MP-GP Receptor A A145M 1.06
511 3S9D MP-GP Receptor A A145G 2.08
512 3S9D MP-GP Receptor A A145G 2.16
513 3S9D MP-GP Receptor A M148A 2.29
514 3S9D MP-GP Receptor A M148A 2.40
515 3S9D MP-GP Receptor A R149A 3.07
516 3S9D MP-GP Receptor A R149A 3.18
517 3S9D MP-GP Receptor A S152A 0.90
518 3S9D MP-GP Receptor A S152A 1.10
519 3S9D MP-GP Receptor A L153A 1.34
520 3S9D MP-GP Receptor A L153A 1.64
521 3S9D MP-GP Receptor A N156A -0.08
522 4JRA MP-GP Enzyme A R1294A 1.79
523 4K71 MP-GP Miscellaneous A A420T -0.53
524 4K71 MP-GP Miscellaneous A H464A 1.05
525 4K71 MP-GP Miscellaneous A H464F 1.01
526 4K71 MP-GP Miscellaneous A G505E -0.60
527 6BX4 MP-GP Transporter C Y84W 0.45
528 6BX4 MP-GP Transporter C Y84I 0.55
529 6BX4 MP-GP Transporter C Y84F -0.28
530 6BX4 MP-GP Transporter C Y80W 0.46
531 6BX4 MP-GP Transporter C Y80F 0.33
532 6BX4 MP-GP Transporter C Y78F 1.03
533 6BX4 MP-GP Transporter C T29V 0.33
534 6BX4 MP-GP Transporter C T29A 0.82
535 6BX4 MP-GP Transporter C L83Y 0.03
536 6BX4 MP-GP Transporter C L83I 0.03
537 6BX5 MP-GP Transporter C T29S 2.43
538 6BX5 MP-GP Transporter C T29V 1.40
539 6BX5 MP-GP Transporter C Y78F 1.20
540 6BX5 MP-GP Transporter C Y78W 0.46
541 6BX5 MP-GP Transporter C Y78I 1.70
542 6BX5 MP-GP Transporter C S80A 1.47
543 6BX5 MP-GP Transporter C E86D 1.20
544 1A22 MP-GP Receptor A A182C -1.02
545 1A22 MP-GP Receptor A A171D -1.16
546 1A22 MP-GP Receptor A E26D 0.13
547 1A22 MP-GP Receptor A A174E 0.90
548 1A22 MP-GP Receptor A A186E 0.14
549 1A22 MP-GP Receptor A A56E -0.84
550 1A22 MP-GP Receptor A A65E 0.31
551 1A22 MP-GP Receptor A A66E -0.44
552 1A22 MP-GP Receptor A A176F -1.64
553 1A22 MP-GP Receptor A Y176F -1.27
554 1A22 MP-GP Receptor A A191F -0.19
555 1A22 MP-GP Receptor A A25F 0.27
556 1A22 MP-GP Receptor A A18H 0.21
557 1A22 MP-GP Receptor A A21H 0.66
558 1A22 MP-GP Receptor A A179I -0.59
559 1A22 MP-GP Receptor A M179I -0.59
560 1A22 MP-GP Receptor A A168K -0.05
561 1A22 MP-GP Receptor A A172K -1.54
562 1A22 MP-GP Receptor A A63N -0.71
563 1A22 MP-GP Receptor A A68Q -0.99
564 1A22 MP-GP Receptor A A167R 0.16
565 1A22 MP-GP Receptor A A178R -2.41
566 1A22 MP-GP Receptor A K178R -0.95
567 1A22 MP-GP Receptor A N178R -1.27
568 1A22 MP-GP Receptor A A183R -0.44
569 1A22 MP-GP Receptor A A64R -1.80
570 1A22 MP-GP Receptor A K64R 0.31
571 1A22 MP-GP Receptor A A62S -0.61
572 1A22 MP-GP Receptor A S175T -1.69
573 1A22 MP-GP Receptor A A164Y -0.76
574 1BP3 MP-GP Receptor A A18H -0.19
575 1BP3 MP-GP Receptor A A21H 0.18
576 1BP3 MP-GP Receptor A A25F -1.15
577 1BP3 MP-GP Receptor A A62S -1.41
578 1BP3 MP-GP Receptor A A63N -0.86
579 1BP3 MP-GP Receptor A A64R -0.35
580 1BP3 MP-GP Receptor A A65E -0.55
581 1BP3 MP-GP Receptor A A68Q -0.11
582 1BP3 MP-GP Receptor A A164Y -0.45
583 1BP3 MP-GP Receptor A A167R -2.12
584 1BP3 MP-GP Receptor A A168K -1.73
585 1BP3 MP-GP Receptor A A171D -0.07
586 1BP3 MP-GP Receptor A A172K -2.02
587 1BP3 MP-GP Receptor A A174E -0.17
588 1BP3 MP-GP Receptor A S175T -0.49
589 1BP3 MP-GP Receptor A A176F -1.94
590 1BP3 MP-GP Receptor A A178R -1.15
591 1BP3 MP-GP Receptor A A179I -0.35
592 1BP3 MP-GP Receptor A M179I 0.16
593 1BP3 MP-GP Receptor A A183R -0.57
594 1BP3 MP-GP Receptor A A188S 0.30
595 1F47 MP-GP Enzyme A A4D -0.69
596 1F47 MP-GP Enzyme A A5Y -0.87
597 1F47 MP-GP Enzyme A A6L -0.92
598 1F47 MP-GP Enzyme A A7D -1.73
599 1F47 MP-GP Enzyme A G7D -1.14
600 1F47 MP-GP Enzyme A S7D -2.06
601 1F47 MP-GP Enzyme A A8I -2.51
602 1F47 MP-GP Enzyme A A9P 0.06
603 1F47 MP-GP Enzyme A A11F -2.44
604 1F47 MP-GP Enzyme A A12L -2.29
605 1F47 MP-GP Enzyme A A14K 0.04
606 1F47 MP-GP Enzyme A A15Q 0.05
607 1FSS MP-GP Enzyme B V8T -0.37
608 1FSS MP-GP Enzyme B I9T 0.23
609 1FSS MP-GP Enzyme B N9T -1.20
610 1FSS MP-GP Enzyme B K11R -0.32
611 1FSS MP-GP Enzyme B S12A -0.32
612 1FSS MP-GP Enzyme B F27R -2.43
613 1FSS MP-GP Enzyme B M27R -2.66
614 1FSS MP-GP Enzyme B Y27R -2.63
615 1FSS MP-GP Enzyme B K29H 0.62
616 1FSS MP-GP Enzyme B R29H 1.49
617 1FSS MP-GP Enzyme B R32K -1.08
618 1FSS MP-GP Enzyme B F33M -0.94
619 1FSS MP-GP Enzyme B L33M -0.96
620 1FSS MP-GP Enzyme B Q33M -1.57
621 1FSS MP-GP Enzyme B Y33M -1.39
622 1FSS MP-GP Enzyme B T34V -1.59
623 1FSS MP-GP Enzyme B W35L -1.45
624 1FSS MP-GP Enzyme B F47N -0.49
625 1FSS MP-GP Enzyme B R47N 0.53
626 1FSS MP-GP Enzyme B W47N -0.12
627 1IAR MP-GP Transporter A A5I -1.17
628 1IAR MP-GP Transporter A R5I -0.80
629 1IAR MP-GP Transporter A A6T 0.10
630 1IAR MP-GP Transporter A D6T -1.39
631 1IAR MP-GP Transporter A A8Q 0.02
632 1IAR MP-GP Transporter A R8Q -0.04
633 1IAR MP-GP Transporter A Q9E -3.11
634 1IAR MP-GP Transporter A E12K -0.14
635 1IAR MP-GP Transporter A S12K 0.01
636 1IAR MP-GP Transporter A A13T -0.98
637 1IAR MP-GP Transporter A D13T 0.22
638 1IAR MP-GP Transporter A A53R -1.71
639 1IAR MP-GP Transporter A Q53R -0.84
640 1IAR MP-GP Transporter A A56Y -0.93
641 1IAR MP-GP Transporter A A78Q -0.12
642 1IAR MP-GP Transporter A E78Q -0.24
643 1IAR MP-GP Transporter A A81R -0.48
644 1IAR MP-GP Transporter A E81R -1.46
645 1IAR MP-GP Transporter A A82F 0.09
646 1IAR MP-GP Transporter A D82F 0.58
647 1IAR MP-GP Transporter A A84K -0.34
648 1IAR MP-GP Transporter A D84K -1.88
649 1IAR MP-GP Transporter A A85R -0.43
650 1IAR MP-GP Transporter A E85R -1.22
651 1IAR MP-GP Transporter A A88R -3.75
652 1IAR MP-GP Transporter A Q88R -2.83
653 1IAR MP-GP Transporter A A89N -1.56
654 1IAR MP-GP Transporter A A91W -0.73
655 1IAR MP-GP Transporter A D91W -1.31
656 1KTZ MP-GP Enzyme A A25R -1.48
657 1KTZ MP-GP Enzyme A K25R -1.15
658 1KTZ MP-GP Enzyme A A94R -2.88
659 1KTZ MP-GP Enzyme A K94R -2.20
660 1KTZ MP-GP Enzyme A I92V -0.24
661 1P6A MP-GP Miscellaneous A Y489S 1.25
662 2AJF MP-GP Transporter E K479N -2.01
663 2AJF MP-GP Transporter E S487T -1.82
664 2J1K MP-GP Miscellaneous C D370G -0.18
665 2J1K MP-GP Miscellaneous C A384R -0.76
666 2REX MP-GP Miscellaneous B F114Y 0.00
667 3BP8 MP-GP Miscellaneous A A136F -0.71
668 3BPO MP-GP Receptor A A11R -0.26
669 3BPO MP-GP Receptor A A18V 0.13
670 3BPO MP-GP Receptor A A87D -0.29
671 3BPO MP-GP Receptor A A88T -0.02
672 3BPO MP-GP Receptor A A89K -1.20
673 3BPO MP-GP Receptor A A90I -1.37
674 3BPO MP-GP Receptor A A91E -1.23
675 3MZG MP-GP Receptor A A173H -1.21
676 3MZG MP-GP Receptor A A195H -0.37
677 3N06 MP-GP Receptor A A27H -0.12
678 3N0P MP-GP Receptor A A30H -0.36
679 3NCB MP-GP Receptor A A180H -1.63
680 3Q3J MP-GP Miscellaneous B F114Y -0.21
681 3S9D MP-GP Receptor A A15L -1.28
682 3S9D MP-GP Receptor A A15L -1.96
683 3S9D MP-GP Receptor A A16M -0.12
684 3S9D MP-GP Receptor A A22R -0.17
685 3S9D MP-GP Receptor A A24I 0.13
686 3S9D MP-GP Receptor A A25S 0.08
687 3S9D MP-GP Receptor A A25S 0.21
688 3S9D MP-GP Receptor A A26L -1.01
689 3S9D MP-GP Receptor A A26L -1.02
690 3S9D MP-GP Receptor A A26L -1.49
691 3S9D MP-GP Receptor A A27F -0.52
692 3S9D MP-GP Receptor A A27F -0.90
693 3S9D MP-GP Receptor A V30L -2.64
694 3S9D MP-GP Receptor A A30L -3.75
695 3S9D MP-GP Receptor A A30L -3.86
696 3S9D MP-GP Receptor A Q33R -6.08
697 3S9D MP-GP Receptor A K33R -4.67
698 3S9D MP-GP Receptor A A33R -5.42
699 3S9D MP-GP Receptor A A34H -0.41
700 3S9D MP-GP Receptor A A34H -0.57
701 3S9D MP-GP Receptor A A35D -0.24
702 3S9D MP-GP Receptor A A35D -0.25
703 3S9D MP-GP Receptor A A79T -0.17
704 3S9D MP-GP Receptor A A80L -0.30
705 3S9D MP-GP Receptor A A96E -0.17
706 3S9D MP-GP Receptor A A144R -2.18
707 3S9D MP-GP Receptor A A144R -2.18
708 3S9D MP-GP Receptor A M145A -1.06
709 3S9D MP-GP Receptor A G145A -2.08
710 3S9D MP-GP Receptor A G145A -2.16
711 3S9D MP-GP Receptor A A148M -2.29
712 3S9D MP-GP Receptor A A148M -2.40
713 3S9D MP-GP Receptor A A149R -3.07
714 3S9D MP-GP Receptor A A149R -3.18
715 3S9D MP-GP Receptor A A152S -0.90
716 3S9D MP-GP Receptor A A152S -1.10
717 3S9D MP-GP Receptor A A153L -1.34
718 3S9D MP-GP Receptor A A153L -1.64
719 3S9D MP-GP Receptor A A156N 0.08
720 4JRA MP-GP Enzyme A A1294R -1.79
721 4K71 MP-GP Miscellaneous A V418M 0.33
722 4K71 MP-GP Miscellaneous A T420A 0.53
723 4K71 MP-GP Miscellaneous A A464H -1.05
724 4K71 MP-GP Miscellaneous A F464H -1.01
725 4K71 MP-GP Miscellaneous A E505G 0.60
726 4K71 MP-GP Miscellaneous A R505G 0.57
727 6BX4 MP-GP Transporter C I84Y -0.55
728 6BX4 MP-GP Transporter C F84Y 0.28
729 6BX4 MP-GP Transporter C I80Y -0.80
730 6BX4 MP-GP Transporter C F80Y -0.33
731 6BX4 MP-GP Transporter C I83L -0.03
732 6BX4 MP-GP Transporter C N82D 0.06
733 3NCC MP-MP Miscellaneous B A188 H -2.29
734 3NCC MP-MP Miscellaneous B  H188A 2.29
735 1IAR MP-MP Transporter B N72D -4.56
736 6ARQ MP-MP Receptor A H72A -0.30
737 1IAR MP-MP Transporter B Y13A 5.22
738 1IAR MP-MP Transporter B Y183F 3.40
739 1DE4 MP-MP Transporter C Q650F -2.51
740 1IAR MP-MP Transporter B A67D -2.35
741 6AAF MP-MP Miscellaneous B A398Y -4.06
742 4IOP MP-MP Receptor A D162A 3.48
743 4IOP MP-MP Receptor A A162D -3.48
744 1IAR MP-MP Transporter B D72A 4.34
745 6MKZ MP-MP Receptor B Y70A 0.00
746 1IAR MP-MP Transporter B D72N 4.56
747 1IAR MP-MP Transporter B L39A 3.01
748 1IAR MP-MP Transporter B Y183A 3.92
749 6AAF MP-MP Miscellaneous B Y398A 4.06
750 2OMY MP-GP Transporter A S192N -2.18
751 3BPO MP-GP Receptor A K104A 3.23
752 4JRA MP-GP Enzyme A R1156E 3.57
753 5IXD MP-GP Enzyme A E188A 2.88
754 6BX5 MP-GP Transporter C W84Y 2.45
755 6BX5 MP-GP Transporter C E86Q 2.15
756 6BX5 MP-GP Transporter C Y87F 1.80
757 2OMY MP-GP Transporter A N192S 2.18
758 3BPO MP-GP Receptor A A104K -3.23
759 4JRA MP-GP Enzyme A E1156R -3.57
760 5IXD MP-GP Enzyme A A188E -2.88
761 6BX5 MP-GP Transporter C S29T -2.43
762 6BX5 MP-GP Transporter C V29T -1.40
763 6BX5 MP-GP Transporter C A80S -1.47
764 6BX5 MP-GP Transporter C Y84W -2.45
765 6BX5 MP-GP Transporter C Q86E -2.15
766 6BX5 MP-GP Transporter C F87Y -1.80
767 5VWX MP-MP Transporter A L100A 2.73
768 3BPO MP-GP Receptor A M33A 2.33
769 6ATK MP-MP Enzyme A V290G 2.01
770 5IXD MP-MP Enzyme B P264A 2.99