Dataset content | Information |
---|---|
Neutralization profile | 1963 experimentally known neutralizing profile |
Mutational scanning information | For 107 crystal structures; Mutation of each paratope and epitope residue; Calculation of interaction energy and stability (4 different computational methods) Affinity calculation methods: 3; stability calculation methods: 3 |
Dataset type | 1569 antibodies; 211 nanobodies |
Neutralization profile summary | IC50: 1804; EC50: 849; Kd: 568 |
Additional content | 1. Information related to viral protein containing epitope; 2. Information on top 10 similar therapeutic antibodies from Thera-SAbDab database and their percent sequence identity; 3. Summary of the antibody from the respective literature 4. 2D Collier de Perles representation for light and heavy chain |