Statistics of Ab-CoV Database





Dataset content Information
Neutralization profile 1963 experimentally known neutralizing profile
Mutational scanning information For 107 crystal structures;
Mutation of each paratope and epitope residue;
Calculation of interaction energy and stability (4 different computational methods)

Affinity calculation methods: 3;
stability calculation methods: 3

Dataset type 1569 antibodies; 211 nanobodies
Neutralization profile summary IC50: 1804;
EC50: 849;
Kd: 568
Additional content 1. Information related to viral protein containing epitope;
2. Information on top 10 similar therapeutic antibodies from Thera-SAbDab database and their percent sequence identity;
3. Summary of the antibody from the respective literature
4. 2D Collier de Perles representation for light and heavy chain