A Model to predict the absolute aggregation rate of native amyloidogenic protein

Protein deposites called amyloids are directly linked with several diseases including neurodegeneratinve diseases, diabetes, AL amyloidosis etc. On a positive note, they also have potential commercial applications as nano-materials with desired mechanical characteristics. Amyloids have been extensively studied for their role in disease in-vitro. However, These experiments are time consuming and expensive. This tool "AbsoluRATE-Pred" is designed to help the researchers by:
(i) providing them a priori information on aggregation kinetics of proteins,
(ii) identifying the physico-chemical properties involved in aggregation.
(iii)AbsoluRATE-Pred prediction model along with AnuPP, AggreRATE-Disc and AggreRATE-Pred can be used for designing proteins will less or more aggregation capability.

Click Here to Predict the absolute aggregation rate of amyloidogenic protein

If you want to know more about the webserver or need help on "how to use server" click here:


If you want to see the dataset used in the study, click here:

Dataset used in the study

Sequences in FASTA format