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ANuPP


           Aggregation Nucleation Prediction for Proteins (ANuPP) is a meta-classifier developed and trained to identify amyloid-fibril forming peptides and regions in protein sequences. In addition, ANuPP server also acts as a repository for the ANuPP prediction results. The database section of the server contains two subsections:


  • 1 Human proteome
  • 2 Hexapeptides

    • The "Human proteome" subsection lists the predicted APRs in human proteins along with relevent details. The "Hexapeptides" subsection lists the prediction score of all 64 million peptides. We believe the data presented in the database section could be useful to the scientifc community.


    Incase of any requests or queries, please contact us.

References:

  • TANGO: Fernandez-Escamilla,A.-M. et al. (2004) Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins. Nat. Biotech-nol., 22, 13026.
  • WALTZ: Maurer-Stroh,S. et al. (2010) Exploring the sequence determinants of amyloid structure using position-specific scoring matrices. Nat. Methods, 7, 237242.