MPTherm is a specific thermodynamic database of membrane proteins and their mutants and it is available at https://www.iitm.ac.in/bioinfo/mptherm/index.php
VariBench is a benchmark database, which contains information for experimentally verified effects and datasets that have been used for developing and testing the performance of stability prediction tools. Also, noted that these data were curated from the ProTherm database. The database is available at http://structure.bmc.lu.se/VariBench/
ΔΔG prediction:
FoldX: A protein design algorithm that uses an empirical force field
I-Mutant: A tool for predicting protein stability upon mutation
EASE-MM: Evolutionary, Amino acid, and Structural Encodings with Multiple Models
MUpro: Prediction of Protein Stability Changes for Single Site Mutations from Sequences
SDM: A server for predicting effects of mutations on protein stability
DUET: a server for predicting effects of mutations on protein stability via an integrated computational approach
mCSM: predicting the effect of mutations in proteins using graph-based signatures
MAESTRO: Multi agent stability prediction upon point mutations
AUTOMUTE: Accurate prediction of stability changes in protein mutants
iPTREE-STAB: A web server for discriminating and predicting the stability of proteins (stabilizing or destabilizing)
CUPSAT: A tool to predict changes in protein stability upon point mutations
STRUM: Structure-based stability change prediction upon single-point mutation
ΔTm prediction:
AUTOMUTE: Accurate prediction of stability changes in protein mutants
HoTMuSiC: Predicting protein thermal stability changes upon point mutations using statistical potentials
MPTherm-pred: Analysis and prediction of thermal stability changes upon mutations in transmembrane proteins