PCA-PredProtein-Carbohydrate complex binding Affinity Prediction
Frequently Asked Questions
What is PCA-Pred?
PCA-Pred is a webserver to calculate the binding free energy (ΔG in kcal/mol) of protein-carbohydrate complexes. It uses structure-based features and regression model to predict ΔG in kcal/mol.
What is the advantage of using PCA-Pred?
PCA-Pred uses structure-based features to predict the change in binding affinity (ΔG value, kcal/mol) in protein-carbohydrate complexes.
Note: It does require structural data as input. Thus, it can be used for protein-carbohydrate complexes for which structure is available.
Why is my input is not being accepted by the server?
There are a number of reasons why our server may not accept a given input. Please ensure that:
- The structure contains carbohydrate/sugar ligand(s).
- The mentioned PDB ID and chain identifier is correct and availble in the PDB database.
- The user uploaded PDB file does not match with pdb format.
I am facing issues with the display of the website on my browser.
The website may be best viewed using the latest version of a browser such as Google Chrome or Mozilla Firefox.