Curated Protein Aggregation Database

CPAD 2.0 database contains the following information related to the mechanistic and kinetic aspect of protein aggregation:
(i) Database for amyloid peptides, data on experimentally known amyloid-forming peptides, non-amyloids, their physiochemical features and aggregation propensity. This database can be accessed by clicking on Amyloid Proteins and Peptide.
(ii) Aggregation-Prone Regions (APRs): Experimentally known hot-spot regions prone to aggregation in amyloidogenic protein.
(iii) Database of experimental data collected from the various aggregation related experiments (such as Thioflavin assay, congo-red assay, etc.) to measure the kinetics of protein aggregation. Click on Aggregation Kinetics to access the database.
(iv) Database for structures of aggregation-related proteins. It contains the amyloidogenic proteins/mutants, their fibril structure and complex with aggregation rate inhibitor/enhancer ligand. Click on Structure of Aggregating Proteins to access the database.

References to related databases and web servers

Click Here to know the statistics about this database

Submitting information to the CPAD 2.0 database:

CPAD 2.0 is an integrated database which contains information related to amyloidogenic proteins, Aggregation prone regions, aggregation kinetics and structure of proteins relevant to aggregation. Authors are encouraged to deposit any information related to above topics to our server.
The template CSV files are provided to fill in the respective detail. Please download the Template files for the respective dataset from here.

If you have used our dataset in your work. Please cite us:
[Citation: coming soon]

Please carefully read the TUTORIAL page before using the database.


Coming soon.. NuAPRpred
April 15, 2019

An effective method to predict the aggregation-prone region in proteins/peptides.

Coming soon...
CPAD 2.0 is online
April 15, 2019

Several improvements in the user interface.
Updated the database.

See the statistics page for more detail.
AggreRATE-Pred is online
March 24, 2019*

AggreRATE-Pred can quantitatively predict the change in aggregation rate.

AggreRATE-Pred link
AggreRATE-Disc is online
June 24, 2018

AggreRATE-Disc can predict the aggregation rate enhancer or mitigator mutations using sequence information.

AggreRATE-Disc link