CPAD 2.0

Entry	Peptide	Length	Class	Protein Name	UniProt ID	Mutant	Reference	PMID	Source Database
P-1381	WPNGIT	6	Non-amyloid	Low-density lipoprotein receptor (LDL receptor)	P01130	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1382	WPNVIT	6	Amyloid	Low-density lipoprotein receptor (LDL receptor)	P01130	G565V	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1383	WQIVYK	6	amyloid	Microtubule-associated protein tau (PHF-tau)	P10636	V623W	Switch Lab	SwitchLab	Waltz-DB 2.0
P-1384	WSFYLL	6	Non-amyloid	Beta-2-microglobulin	P61769	No	Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4074-8.	16537487	CPAD, Waltz-DB 2.0, AmyLoad
P-1385	WTFNLY	6	Amyloid	Kv channel-interacting protein 1 (KChIP1)	Q9NZI2	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1386	WTVIIE	6	Amyloid			No	Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4074-8.	16537487	CPAD, Waltz-DB 2.0, AmyLoad
P-1387	WTVNYS	6	Amyloid	WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP)	Q8NI36	No	BMC Bioinformatics. 2013;14 Suppl 8:S6.	23815227	CPAD, Waltz-DB 2.0
P-1388	WVENYP	6	Non-amyloid			No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	CPAD, Waltz-DB 2.0, AmyLoad
P-1389	WVFWIG	6	Amyloid	Aquaporin-2 (AQP-2)	P41181	No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	CPAD, Waltz-DB 2.0, AmyLoad
P-1390	WYFYIQ	6	Non-amyloid			No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	CPAD, Waltz-DB 2.0, AmyLoad
P-1391	YAELIV	6	Amyloid			No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	CPAD, Waltz-DB 2.0, AmyLoad
P-1392	YASEIE	6	Non-amyloid			No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	CPAD, Waltz-DB 2.0, AmyLoad
P-1393	YASNNN	6	Non-amyloid	Transcriptional regulatory protein SAP30	P38429	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1394	YATVYV	6	amyloid	Apolipoprotein A-I (ApoA-I)	P02647	L38Y	Switch Lab	SwitchLab	Waltz-DB 2.0
P-1395	YGGGGN	6	Non-amyloid	Major curlin subunit	P28307	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1396	YGGGNS	6	Non-amyloid	Major curlin subunit	P28307	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1397	YGQQNQ	6	Non-amyloid	RNA-binding protein FUS	P35637	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1398	YGQQQS	6	Non-amyloid	RNA-binding protein FUS	P35637	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1399	YGQQSY	6	Non-amyloid	RNA-binding protein FUS	P35637	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1400	YGQSSY	6	Non-amyloid	RNA-binding protein FUS	P35637	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1401	YHLAMA	6	amyloid			No	Sci Rep. 2015 Oct 6;5:14794.	26440769	Waltz-DB 2.0
P-1402	YIFNNC	6	Amyloid	Protein unc-13 homolog B (Munc13-2) (munc13)	O14795	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1403	YIFNNM	6	Non-amyloid	Alpha-mannosidase 2	Q16706	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1404	YKNFNY	6	Non-amyloid	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)	P05453	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1405	YLEIII	6	Non-amyloid			No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	CPAD, Waltz-DB 2.0, AmyLoad
P-1406	YLFLQY	6	Amyloid	SLIT and NTRK-like protein 5 (Leucine-rich repeat-containing protein 11)	O94991	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1407	YLGNNS	6	Non-amyloid	[PIN+] prion protein RNQ1	P25367	No	Switch Lab	SwitchLab	Waltz-DB 2.0, AmyLoad
P-1408	YLLWYC	6	Amyloid	Vitronectin (VN) (S-protein) (Serum-spreading factor)	P04004	No	BMC Bioinformatics. 2013;14 Suppl 8:S6.	23815227	CPAD, Waltz-DB 2.0
P-1409	YLLYYT	6	Amyloid	Beta-2-microglobulin	P61769	No	Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):87-92.	14691246	Waltz-DB 2.0, AmyLoad
P-1410	YLNWYQ	6	Amyloid			No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	CPAD, Waltz-DB 2.0, AmyLoad

Sequence

1

M

G

P

W

G

W

K

L

R

W

T

V

A

L

A

G

T

A

V

G

D

R

C

E

R

N

E

F

Q

C

Q

D

G

K

C

I

S

Y

K

W

V

C

D

G

S

A

E

C

Q

D

G

S

D

E

S

Q

60

61

E

T

C

L

S

V

T

C

K

S

G

D

F

S

C

G

R

V

N

R

C

I

P

Q

F

W

R

C

D

G

Q

V

D

C

D

N

G

S

D

E

Q

G

C

P

K

T

C

S

Q

D

E

F

R

C

H

D

G

K

120

121

C

I

S

R

Q

F

V

C

D

S

D

R

D

C

L

D

G

S

D

E

A

S

C

P

V

L

T

C

G

P

A

S

F

Q

C

N

S

T

C

I

P

Q

L

W

A

C

D

N

D

P

D

C

E

D

G

S

D

E

W

180

181

P

Q

R

C

R

G

L

Y

V

F

Q

G

D

S

P

C

S

A

F

E

F

H

C

L

S

G

E

C

I

H

S

W

R

C

D

G

P

D

C

K

D

K

S

D

E

N

C

A

V

A

T

C

R

P

D

E

240

241

F

Q

C

S

D

G

N

C

I

H

G

S

R

Q

C

D

R

E

Y

D

C

K

D

M

S

D

E

V

G

C

V

N

V

T

L

C

E

G

P

N

K

F

K

C

H

S

G

E

C

I

T

L

D

K

V

C

N

M

A

R

300

301

D

C

R

D

W

S

D

E

P

I

K

E

C

G

T

N

E

C

L

D

N

G

C

S

H

V

C

N

D

L

K

I

G

Y

E

C

L

C

P

D

G

F

Q

L

V

A

Q

R

C

E

D

I

D

E

C

Q

D

360

361

P

D

T

C

S

Q

L

C

V

N

L

E

G

Y

K

C

Q

C

E

G

F

Q

L

D

P

H

T

K

A

C

K

A

V

G

S

I

A

Y

L

F

T

N

R

H

E

V

R

K

M

T

L

D

R

S

E

Y

T

420

421

S

L

I

P

N

L

R

N

V

A

L

D

T

E

V

A

S

N

R

I

Y

W

S

D

L

S

Q

R

M

I

C

S

T

Q

L

D

R

A

H

G

V

S

Y

D

T

V

I

S

R

D

I

Q

A

P

D

G

L

A

480

481

V

D

W

I

H

S

N

I

Y

W

T

D

S

V

L

G

T

V

S

V

A

D

T

K

G

V

K

R

K

T

L

F

R

E

N

G

S

K

P

R

A

I

V

D

P

V

H

G

F

M

Y

W

T

D

W

G

T

P

A

540

541

K

I

K

G

L

N

G

V

D

I

Y

S

L

V

T

E

N

I

Q

W

P

N

G

I

T

L

D

L

S

G

R

L

Y

W

V

D

S

K

L

H

S

I

S

I

D

V

N

G

N

R

K

T

I

L

E

600

601

D

E

K

R

L

A

H

P

F

S

L

A

V

F

E

D

K

V

F

W

T

D

I

N

E

A

I

F

S

A

N

R

L

T

G

S

D

V

N

L

A

E

N

L

S

P

E

D

M

V

L

F

H

N

L

T

Q

660

661

P

R

G

V

N

W

C

E

R

T

L

S

N

G

C

Q

Y

L

C

L

P

A

P

Q

I

N

P

H

S

P

K

F

T

C

A

C

P

D

G

M

L

A

R

D

M

R

S

C

L

T

E

A

E

A

V

A

720

721

T

Q

E

T

S

T

V

R

L

K

V

S

T

A

V

R

T

Q

H

T

R

P

V

P

D

T

S

R

L

P

G

A

T

P

G

L

T

V

E

I

V

T

M

S

H

Q

A

L

G

D

V

A

G

R

G

N

780

781

E

K

P

S

V

R

A

L

S

I

V

L

P

I

V

L

V

F

L

C

L

G

V

F

L

W

K

N

W

R

L

K

N

I

N

S

I

N

F

D

N

P

V

Y

Q

K

T

E

D

E

V

H

I

C

H

840

841

N

Q

D

G

Y

S

Y

P

S

R

Q

M

V

S

L

E

D

V

A

860

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1381
Peptide:	WPNGIT
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P01130
UniProt Name:	LDLR_HUMAN
Protein Name:	Low-density lipoprotein receptor (LDL receptor)
Position:	562-567

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	50.0
NuAPRpred:	-0.51
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-26.2
Area of the profile Above Threshold (AGGRESCAN):	0.16
Best Energy Score (PASTA 2.0):	-0.7
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

G

P

W

G

W

K

L

R

W

T

V

A

L

A

G

T

A

V

G

D

R

C

E

R

N

E

F

Q

C

Q

D

G

K

C

I

S

Y

K

W

V

C

D

G

S

A

E

C

Q

D

G

S

D

E

S

Q

60

61

E

T

C

L

S

V

T

C

K

S

G

D

F

S

C

G

R

V

N

R

C

I

P

Q

F

W

R

C

D

G

Q

V

D

C

D

N

G

S

D

E

Q

G

C

P

K

T

C

S

Q

D

E

F

R

C

H

D

G

K

120

121

C

I

S

R

Q

F

V

C

D

S

D

R

D

C

L

D

G

S

D

E

A

S

C

P

V

L

T

C

G

P

A

S

F

Q

C

N

S

T

C

I

P

Q

L

W

A

C

D

N

D

P

D

C

E

D

G

S

D

E

W

180

181

P

Q

R

C

R

G

L

Y

V

F

Q

G

D

S

P

C

S

A

F

E

F

H

C

L

S

G

E

C

I

H

S

W

R

C

D

G

P

D

C

K

D

K

S

D

E

N

C

A

V

A

T

C

R

P

D

E

240

241

F

Q

C

S

D

G

N

C

I

H

G

S

R

Q

C

D

R

E

Y

D

C

K

D

M

S

D

E

V

G

C

V

N

V

T

L

C

E

G

P

N

K

F

K

C

H

S

G

E

C

I

T

L

D

K

V

C

N

M

A

R

300

301

D

C

R

D

W

S

D

E

P

I

K

E

C

G

T

N

E

C

L

D

N

G

C

S

H

V

C

N

D

L

K

I

G

Y

E

C

L

C

P

D

G

F

Q

L

V

A

Q

R

C

E

D

I

D

E

C

Q

D

360

361

P

D

T

C

S

Q

L

C

V

N

L

E

G

Y

K

C

Q

C

E

G

F

Q

L

D

P

H

T

K

A

C

K

A

V

G

S

I

A

Y

L

F

T

N

R

H

E

V

R

K

M

T

L

D

R

S

E

Y

T

420

421

S

L

I

P

N

L

R

N

V

A

L

D

T

E

V

A

S

N

R

I

Y

W

S

D

L

S

Q

R

M

I

C

S

T

Q

L

D

R

A

H

G

V

S

Y

D

T

V

I

S

R

D

I

Q

A

P

D

G

L

A

480

481

V

D

W

I

H

S

N

I

Y

W

T

D

S

V

L

G

T

V

S

V

A

D

T

K

G

V

K

R

K

T

L

F

R

E

N

G

S

K

P

R

A

I

V

D

P

V

H

G

F

M

Y

W

T

D

W

G

T

P

A

540

541

K

I

K

G

L

N

G

V

D

I

Y

S

L

V

T

E

N

I

Q

W

P

N

G

I

T

L

D

L

S

G

R

L

Y

W

V

D

S

K

L

H

S

I

S

I

D

V

N

G

N

R

K

T

I

L

E

600

601

D

E

K

R

L

A

H

P

F

S

L

A

V

F

E

D

K

V

F

W

T

D

I

N

E

A

I

F

S

A

N

R

L

T

G

S

D

V

N

L

A

E

N

L

S

P

E

D

M

V

L

F

H

N

L

T

Q

660

661

P

R

G

V

N

W

C

E

R

T

L

S

N

G

C

Q

Y

L

C

L

P

A

P

Q

I

N

P

H

S

P

K

F

T

C

A

C

P

D

G

M

L

A

R

D

M

R

S

C

L

T

E

A

E

A

V

A

720

721

T

Q

E

T

S

T

V

R

L

K

V

S

T

A

V

R

T

Q

H

T

R

P

V

P

D

T

S

R

L

P

G

A

T

P

G

L

T

V

E

I

V

T

M

S

H

Q

A

L

G

D

V

A

G

R

G

N

780

781

E

K

P

S

V

R

A

L

S

I

V

L

P

I

V

L

V

F

L

C

L

G

V

F

L

W

K

N

W

R

L

K

N

I

N

S

I

N

F

D

N

P

V

Y

Q

K

T

E

D

E

V

H

I

C

H

840

841

N

Q

D

G

Y

S

Y

P

S

R

Q

M

V

S

L

E

D

V

A

860

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1382
Peptide:	WPNVIT
Length:	6
Classification:	Amyloid
Mutation(s):	G565V
Structure(s):	No structures

Protein Information

UniProt ID:	P01130
UniProt Name:	LDLR_HUMAN
Protein Name:	Low-density lipoprotein receptor (LDL receptor)
Position:	562-567

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	66.67
NuAPRpred:	-0.35
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	16.4
Area of the profile Above Threshold (AGGRESCAN):	1.32
Best Energy Score (PASTA 2.0):	-4.04
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

A

E

P

R

Q

E

F

E

V

M

E

D

H

A

G

T

Y

G

L

G

D

R

K

D

Q

G

Y

T

M

H

Q

D

Q

E

G

D

T

D

A

G

L

K

E

S

P

L

Q

T

P

T

E

D

G

S

E

P

G

60

61

S

E

T

S

D

A

K

S

T

P

T

A

E

D

V

T

A

P

L

V

D

E

G

A

P

G

K

Q

A

Q

P

H

T

E

I

P

E

G

T

A

E

A

G

I

G

D

T

P

S

L

E

D

E

A

G

120

121

H

V

T

Q

E

P

E

S

G

K

V

Q

E

G

F

L

R

E

P

G

P

G

L

S

H

Q

L

M

S

G

M

P

G

A

P

L

P

E

G

P

R

E

A

T

R

Q

P

S

G

T

G

P

E

D

T

E

G

180

181

G

R

H

A

P

E

L

K

H

Q

L

G

D

L

H

Q

E

G

P

L

K

G

A

G

K

E

R

P

G

S

K

E

V

D

E

D

R

D

V

D

E

S

P

Q

D

S

P

S

K

A

S

P

A

240

241

Q

D

G

R

P

Q

T

A

R

E

A

T

S

I

P

G

F

P

A

E

G

A

I

P

L

P

V

D

F

L

S

K

V

S

T

E

I

P

A

S

E

P

D

G

P

S

V

G

R

A

K

G

Q

D

A

P

L

E

300

301

F

T

F

H

V

E

I

T

P

N

V

Q

K

E

Q

A

H

S

E

H

L

G

R

A

F

P

G

A

P

G

E

G

P

E

A

R

G

P

S

L

G

E

D

T

K

E

A

D

L

P

E

P

S

E

K

Q

P

A

360

361

A

P

R

G

K

P

V

S

R

V

P

Q

L

K

A

R

M

V

S

K

S

K

D

G

T

G

S

D

K

A

K

T

S

T

R

S

A

K

T

L

K

N

R

P

C

L

S

P

K

H

P

T

P

G

S

420

421

D

P

L

I

Q

P

S

P

A

V

C

P

E

P

S

P

K

Y

V

S

V

T

S

R

T

G

S

G

A

K

E

M

K

L

K

G

A

D

G

K

T

K

I

A

T

P

R

G

A

P

G

Q

K

480

481

G

Q

A

N

A

T

R

I

P

A

K

T

P

A

P

K

T

P

S

G

E

P

K

S

G

D

R

S

G

Y

S

P

G

S

P

G

T

P

G

S

R

S

R

T

P

S

L

P

T

P

T

R

E

P

540

541

K

V

A

V

R

T

P

K

S

P

S

A

K

S

R

L

Q

T

A

P

V

P

M

P

D

L

K

N

V

K

S

K

I

G

S

T

E

N

L

K

H

Q

P

G

K

V

Q

I

N

K

L

D

600

601

L

S

N

V

Q

S

K

C

G

S

K

D

N

I

K

H

V

P

G

S

V

Q

I

V

Y

K

P

V

D

L

S

K

V

T

S

K

C

G

S

L

G

N

I

H

K

P

G

Q

V

E

V

K

S

E

K

660

661

L

D

F

K

D

R

V

Q

S

K

I

G

S

L

D

N

I

T

H

V

P

G

N

K

I

E

T

H

K

L

T

F

R

E

N

A

K

A

K

T

D

H

G

A

E

I

V

Y

K

S

P

V

S

G

D

T

720

721

S

P

R

H

L

S

N

V

S

T

G

S

I

D

M

V

D

S

P

Q

L

A

T

L

A

D

E

V

S

A

S

L

A

K

Q

G

L

758

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1383
Peptide:	WQIVYK
Length:	6
Classification:	amyloid
Mutation(s):	V623W
Structure(s):	No structures

Protein Information

UniProt ID:	P10636
UniProt Name:	TAU_HUMAN
Protein Name:	Microtubule-associated protein tau (PHF-tau)
Position:	623-628

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0

Derived Information

Net Charge:	1
Absolute Charge:	1
Hydrophobicity:	66.67
NuAPRpred:	0.72
Tango:	8.63

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	50.4
Area of the profile Above Threshold (AGGRESCAN):	3.31
Best Energy Score (PASTA 2.0):	-3.88
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

S

R

S

V

A

L

A

V

L

A

L

S

L

S

G

L

E

A

I

Q

R

T

P

K

I

Q

V

Y

S

R

H

P

A

E

N

G

K

S

N

F

L

N

C

Y

V

S

G

F

H

P

S

D

I

E

V

D

L

60

61

K

N

G

E

R

I

E

K

V

E

H

S

D

L

S

F

S

K

D

W

S

F

Y

L

Y

T

E

F

T

P

T

E

K

D

E

Y

A

C

R

V

N

H

V

T

L

S

Q

P

K

I

V

K

W

D

R

D

M

119

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1384
Peptide:	WSFYLL
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P61769
UniProt Name:	B2MG_HUMAN
Protein Name:	Beta-2-microglobulin
Position:	80-85

Literature

PMID:	16537487
Reference:	Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4074-8.
source:	CPAD, Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	83.33
NuAPRpred:	0.89
Tango:	3.25

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	78.9
Area of the profile Above Threshold (AGGRESCAN):	5.06
Best Energy Score (PASTA 2.0):	-3.07
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

G

A

V

M

G

T

F

S

L

Q

T

K

Q

R

P

S

K

D

I

A

W

Y

Q

Y

Q

R

D

K

I

E

D

E

L

E

M

T

M

V

C

H

R

P

E

G

L

E

Q

L

E

A

Q

T

N

F

T

60

61

K

R

E

L

Q

V

L

Y

R

G

F

K

N

E

C

P

S

G

V

N

E

D

T

F

K

Q

I

Y

A

Q

F

P

H

G

D

A

S

T

Y

A

H

Y

L

F

N

A

F

D

T

Q

T

G

S

V

K

F

E

120

121

D

F

V

T

A

L

S

I

L

R

G

T

V

H

E

K

L

R

W

T

F

N

L

Y

D

I

N

K

D

G

Y

I

N

K

E

M

D

I

V

K

A

I

Y

D

M

G

K

Y

T

Y

P

V

L

K

E

D

180

181

T

P

R

Q

H

V

D

V

F

Q

K

M

D

K

N

K

D

G

I

V

T

L

D

E

F

L

E

S

C

Q

E

D

N

I

M

R

S

L

Q

L

F

Q

N

V

M

227

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1385
Peptide:	WTFNLY
Length:	6
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	Q9NZI2
UniProt Name:	KCIP1_HUMAN
Protein Name:	Kv channel-interacting protein 1 (KChIP1)
Position:	140-145

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	66.67
NuAPRpred:	0.68
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	29.2
Area of the profile Above Threshold (AGGRESCAN):	1.95
Best Energy Score (PASTA 2.0):	-3.04
Aggregate Orientation (PASTA 2.0):	Parallel

Peptide details

Entry:	P-1386
Peptide:	WTVIIE
Length:	6
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:
Protein Name:
Position:

Literature

PMID:	16537487
Reference:	Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4074-8.
source:	CPAD, Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	-1
Absolute Charge:	1
Hydrophobicity:	66.67
NuAPRpred:	0.99
Tango:	11.66

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	68.7
Area of the profile Above Threshold (AGGRESCAN):	4.52
Best Energy Score (PASTA 2.0):	-6.93
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

W

T

V

N

Y

S

6

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1387
Peptide:	WTVNYS
Length:	6
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	Q8NI36
UniProt Name:	WDR36_HUMAN
Protein Name:	WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP)
Position:

Literature

PMID:	23815227
Reference:	BMC Bioinformatics. 2013;14 Suppl 8:S6.
source:	CPAD, Waltz-DB 2.0

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	50.0
NuAPRpred:	0.25
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	8.5
Area of the profile Above Threshold (AGGRESCAN):	0.77
Best Energy Score (PASTA 2.0):	-3.4
Aggregate Orientation (PASTA 2.0):	Parallel

Peptide details

Entry:	P-1388
Peptide:	WVENYP
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:
Protein Name:
Position:

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	CPAD, Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	-1
Absolute Charge:	1
Hydrophobicity:	66.67
NuAPRpred:	-0.41
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-28.6
Area of the profile Above Threshold (AGGRESCAN):	0.24
Best Energy Score (PASTA 2.0):	-0.7
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

W

E

L

R

S

I

A

F

S

R

A

V

F

A

E

F

L

A

T

L

F

V

F

G

L

G

S

A

L

N

W

P

Q

A

L

P

S

V

L

Q

I

A

M

A

F

G

L

G

I

G

T

L

V

Q

A

L

G

60

61

H

I

S

G

A

H

I

N

P

A

V

T

V

A

C

L

V

G

C

H

V

S

V

L

R

A

F

Y

V

A

Q

L

G

A

V

A

G

A

L

H

E

I

T

P

A

D

I

R

G

D

L

A

V

N

A

120

121

L

S

N

S

T

A

G

Q

A

V

T

V

E

L

F

L

T

L

Q

L

V

L

C

I

F

A

S

T

D

E

R

G

E

N

P

G

T

P

A

L

S

I

G

F

S

V

A

L

G

H

L

G

I

H

Y

T

G

180

181

C

S

M

N

P

A

R

S

L

A

P

A

V

T

G

K

F

D

H

W

V

F

W

I

G

P

L

V

G

A

I

L

G

S

L

Y

N

Y

V

L

F

P

A

K

S

L

S

E

R

L

A

V

L

K

G

L

240

241

E

P

D

T

D

W

E

R

E

V

R

Q

S

V

E

L

H

S

P

Q

S

L

P

R

G

T

K

A

271

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1389
Peptide:	WVFWIG
Length:	6
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P41181
UniProt Name:	AQP2_HUMAN
Protein Name:	Aquaporin-2 (AQP-2)
Position:	202-207

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	CPAD, Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	83.33
NuAPRpred:	1.02
Tango:	157.08

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	88.3
Area of the profile Above Threshold (AGGRESCAN):	5.81
Best Energy Score (PASTA 2.0):	-6.67
Aggregate Orientation (PASTA 2.0):	Parallel

Peptide details

Entry:	P-1390
Peptide:	WYFYIQ
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:
Protein Name:
Position:

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	CPAD, Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	83.33
NuAPRpred:	0.92
Tango:	211.28

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	78.0
Area of the profile Above Threshold (AGGRESCAN):	5.16
Best Energy Score (PASTA 2.0):	-4.63
Aggregate Orientation (PASTA 2.0):	Parallel

Peptide details

Entry:	P-1391
Peptide:	YAELIV
Length:	6
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:
Protein Name:
Position:

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	CPAD, Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	-1
Absolute Charge:	1
Hydrophobicity:	83.33
NuAPRpred:	0.94
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	32.6
Area of the profile Above Threshold (AGGRESCAN):	2.25
Best Energy Score (PASTA 2.0):	-2.11
Aggregate Orientation (PASTA 2.0):	Parallel

Peptide details

Entry:	P-1392
Peptide:	YASEIE
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:
Protein Name:
Position:

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	CPAD, Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	-2
Absolute Charge:	2
Hydrophobicity:	50.0
NuAPRpred:	0.08
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-30.9
Area of the profile Above Threshold (AGGRESCAN):	0.27
Best Energy Score (PASTA 2.0):	0.58
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

A

R

P

V

N

T

N

A

E

T

E

S

R

G

R

P

T

Q

G

Y

A

S

N

G

S

C

N

G

S

N

S

N

S

N

G

P

60

61

T

S

G

R

T

N

G

K

Q

R

L

T

A

Q

Y

I

K

N

L

I

E

T

H

I

T

D

N

H

P

D

L

R

P

K

S

H

P

M

D

F

E

Y

T

D

A

F

L

R

Y

K

D

H

F

Q

120

121

L

D

V

P

D

N

L

T

L

Q

G

Y

L

G

S

K

L

G

A

K

T

Y

S

Y

K

R

N

T

Q

G

Q

H

D

K

R

I

H

K

R

D

L

A

N

V

R

H

F

D

E

H

S

I

K

E

T

D

C

180

181

I

P

Q

F

I

Y

K

V

K

N

Q

K

F

K

M

E

F

R

G

201

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1393
Peptide:	YASNNN
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P38429
UniProt Name:	SAP30_YEAST
Protein Name:	Transcriptional regulatory protein SAP30
Position:	23-28

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	33.33
NuAPRpred:	-0.31
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-69.3
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	0.73
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

K

A

V

L

T

L

A

V

L

F

L

T

G

S

Q

A

R

H

F

W

Q

D

E

P

Q

S

P

W

D

R

V

K

D

L

A

T

V

Y

V

D

V

L

K

D

S

G

R

D

Y

V

S

Q

F

E

G

S

60

61

A

L

G

K

Q

L

N

L

K

L

D

N

W

D

S

V

T

S

T

F

S

K

L

R

E

Q

L

G

P

V

T

Q

E

F

W

D

N

L

E

K

E

T

E

G

L

R

Q

E

M

S

K

D

L

E

V

K

A

K

120

121

V

Q

P

Y

L

D

F

Q

K

W

Q

E

M

E

L

Y

R

Q

K

V

E

P

L

R

A

E

L

Q

E

G

A

R

Q

K

L

H

E

L

Q

E

K

L

S

P

L

G

E

M

R

D

R

A

R

A

H

V

180

181

D

A

L

R

T

H

L

A

P

Y

S

D

E

L

R

Q

R

L

A

R

L

E

A

L

K

E

N

G

A

R

L

A

E

Y

H

A

K

A

T

E

H

L

S

T

L

S

E

K

A

K

P

A

L

E

D

L

R

Q

240

241

G

L

P

V

L

E

S

F

K

V

S

F

L

S

A

L

E

Y

T

K

L

N

T

Q

267

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1394
Peptide:	YATVYV
Length:	6
Classification:	amyloid
Mutation(s):	L38Y
Structure(s):	No structures

Protein Information

UniProt ID:	P02647
UniProt Name:	APOA1_HUMAN
Protein Name:	Apolipoprotein A-I (ApoA-I)
Position:	38-43

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	83.33
NuAPRpred:	0.68
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	53.1
Area of the profile Above Threshold (AGGRESCAN):	3.41
Best Energy Score (PASTA 2.0):	-4.52
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

K

L

K

V

A

I

A

I

V

F

S

G

S

A

L

A

G

V

P

Q

Y

G

N

H

G

N

S

G

P

N

S

E

L

N

I

Y

Q

Y

G

N

S

A

L

A

L

Q

60

61

T

D

A

R

N

S

D

L

T

I

T

Q

H

G

N

G

A

D

V

G

Q

G

S

D

S

I

D

L

T

Q

R

G

F

G

N

S

A

T

L

D

Q

W

N

G

K

N

S

E

M

T

V

K

Q

F

G

120

121

G

N

G

A

V

D

Q

T

A

S

N

S

V

N

V

T

Q

V

G

F

G

N

A

T

A

H

Q

Y

151

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1395
Peptide:	YGGGGN
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P28307
UniProt Name:	CSGA_ECOLI
Protein Name:	Major curlin subunit
Position:	26-31

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	16.67
NuAPRpred:	-0.52
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-55.2
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	2.08
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

K

L

K

V

A

I

A

I

V

F

S

G

S

A

L

A

G

V

P

Q

Y

G

N

H

G

N

S

G

P

N

S

E

L

N

I

Y

Q

Y

G

N

S

A

L

A

L

Q

60

61

T

D

A

R

N

S

D

L

T

I

T

Q

H

G

N

G

A

D

V

G

Q

G

S

D

S

I

D

L

T

Q

R

G

F

G

N

S

A

T

L

D

Q

W

N

G

K

N

S

E

M

T

V

K

Q

F

G

120

121

G

N

G

A

V

D

Q

T

A

S

N

S

V

N

V

T

Q

V

G

F

G

N

A

T

A

H

Q

Y

151

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1396
Peptide:	YGGGNS
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P28307
UniProt Name:	CSGA_ECOLI
Protein Name:	Major curlin subunit
Position:	50-55

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	16.67
NuAPRpred:	-0.5
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-55.3
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	2.08
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

A

S

N

D

Y

T

Q

A

T

Q

S

Y

G

A

Y

P

T

Q

P

G

Q

G

Y

S

Q

S

Q

P

Y

G

Q

S

Y

S

G

Y

S

Q

S

T

D

T

S

G

Y

G

Q

S

Y

S

Y

G

Q

60

61

S

Q

N

T

G

Y

G

T

Q

S

T

P

Q

G

Y

G

S

T

G

Y

G

S

Q

S

Q

S

Y

G

Q

S

Y

P

G

Y

G

Q

P

A

P

S

T

S

G

S

Y

G

S

Q

S

120

121

S

Y

G

Q

P

Q

S

G

S

Y

S

Q

P

S

Y

G

Q

S

Y

G

Q

S

Y

N

P

Q

G

Y

G

Q

N

Q

Y

N

S

G

N

Y

G

Q

D

180

181

Q

S

M

S

G

S

G

Y

G

N

Q

D

Q

S

G

S

G

Y

G

Q

D

R

G

R

G

R

G

S

G

Y

N

R

S

G

Y

E

240

241

P

R

G

R

G

R

G

R

G

M

G

S

D

R

G

F

N

K

F

G

P

R

D

Q

G

S

R

H

D

S

E

Q

D

N

S

D

N

T

I

F

V

Q

G

L

G

E

N

V

T

I

E

S

300

301

V

A

D

Y

F

K

Q

I

G

I

K

T

N

K

T

G

Q

P

M

I

N

L

Y

T

D

R

E

T

G

K

L

K

G

E

A

T

V

S

F

D

P

S

A

K

A

I

D

W

F

D

G

K

E

F

S

360

361

G

N

P

I

K

V

S

F

A

T

R

A

D

F

N

R

G

N

G

R

G

R

G

R

G

P

M

G

R

G

Y

G

S

G

R

G

F

P

S

G

Q

420

421

Q

R

A

G

D

W

K

C

P

N

P

T

C

E

N

M

N

F

S

W

R

N

E

C

N

Q

C

K

A

P

K

P

D

G

P

G

P

G

S

H

M

G

N

Y

G

D

R

G

R

G

Y

D

480

481

R

G

Y

R

G

R

G

D

R

G

F

R

G

R

G

D

R

G

F

G

P

G

K

M

D

S

R

G

E

H

R

Q

D

R

E

R

P

Y

526

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1397
Peptide:	YGQQNQ
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P35637
UniProt Name:	FUS_HUMAN
Protein Name:	RNA-binding protein FUS
Position:	155-160

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	16.67
NuAPRpred:	-0.35
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-92.5
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	1.45
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

A

S

N

D

Y

T

Q

A

T

Q

S

Y

G

A

Y

P

T

Q

P

G

Q

G

Y

S

Q

S

Q

P

Y

G

Q

S

Y

S

G

Y

S

Q

S

T

D

T

S

G

Y

G

Q

S

Y

S

Y

G

Q

60

61

S

Q

N

T

G

Y

G

T

Q

S

T

P

Q

G

Y

G

S

T

G

Y

G

S

Q

S

Q

S

Y

G

Q

S

Y

P

G

Y

G

Q

P

A

P

S

T

S

G

S

Y

G

S

Q

S

120

121

S

Y

G

Q

P

Q

S

G

S

Y

S

Q

P

S

Y

G

Q

S

Y

G

Q

S

Y

N

P

Q

G

Y

G

Q

N

Q

Y

N

S

G

N

Y

G

Q

D

180

181

Q

S

M

S

G

S

G

Y

G

N

Q

D

Q

S

G

S

G

Y

G

Q

D

R

G

R

G

R

G

S

G

Y

N

R

S

G

Y

E

240

241

P

R

G

R

G

R

G

R

G

M

G

S

D

R

G

F

N

K

F

G

P

R

D

Q

G

S

R

H

D

S

E

Q

D

N

S

D

N

T

I

F

V

Q

G

L

G

E

N

V

T

I

E

S

300

301

V

A

D

Y

F

K

Q

I

G

I

K

T

N

K

T

G

Q

P

M

I

N

L

Y

T

D

R

E

T

G

K

L

K

G

E

A

T

V

S

F

D

P

S

A

K

A

I

D

W

F

D

G

K

E

F

S

360

361

G

N

P

I

K

V

S

F

A

T

R

A

D

F

N

R

G

N

G

R

G

R

G

R

G

P

M

G

R

G

Y

G

S

G

R

G

F

P

S

G

Q

420

421

Q

R

A

G

D

W

K

C

P

N

P

T

C

E

N

M

N

F

S

W

R

N

E

C

N

Q

C

K

A

P

K

P

D

G

P

G

P

G

S

H

M

G

N

Y

G

D

R

G

R

G

Y

D

480

481

R

G

Y

R

G

R

G

D

R

G

F

R

G

R

G

D

R

G

F

G

P

G

K

M

D

S

R

G

E

H

R

Q

D

R

E

R

P

Y

526

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1398
Peptide:	YGQQQS
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P35637
UniProt Name:	FUS_HUMAN
Protein Name:	RNA-binding protein FUS
Position:	143-148

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	16.67
NuAPRpred:	-0.44
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-82.2
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	0.95
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

A

S

N

D

Y

T

Q

A

T

Q

S

Y

G

A

Y

P

T

Q

P

G

Q

G

Y

S

Q

S

Q

P

Y

G

Q

S

Y

S

G

Y

S

Q

S

T

D

T

S

G

Y

G

Q

S

Y

S

Y

G

Q

60

61

S

Q

N

T

G

Y

G

T

Q

S

T

P

Q

G

Y

G

S

T

G

Y

G

S

Q

S

Q

S

Y

G

Q

S

Y

P

G

Y

G

Q

P

A

P

S

T

S

G

S

Y

G

S

Q

S

120

121

S

Y

G

Q

P

Q

S

G

S

Y

S

Q

P

S

Y

G

Q

S

Y

G

Q

S

Y

N

P

Q

G

Y

G

Q

N

Q

Y

N

S

G

N

Y

G

Q

D

180

181

Q

S

M

S

G

S

G

Y

G

N

Q

D

Q

S

G

S

G

Y

G

Q

D

R

G

R

G

R

G

S

G

Y

N

R

S

G

Y

E

240

241

P

R

G

R

G

R

G

R

G

M

G

S

D

R

G

F

N

K

F

G

P

R

D

Q

G

S

R

H

D

S

E

Q

D

N

S

D

N

T

I

F

V

Q

G

L

G

E

N

V

T

I

E

S

300

301

V

A

D

Y

F

K

Q

I

G

I

K

T

N

K

T

G

Q

P

M

I

N

L

Y

T

D

R

E

T

G

K

L

K

G

E

A

T

V

S

F

D

P

S

A

K

A

I

D

W

F

D

G

K

E

F

S

360

361

G

N

P

I

K

V

S

F

A

T

R

A

D

F

N

R

G

N

G

R

G

R

G

R

G

P

M

G

R

G

Y

G

S

G

R

G

F

P

S

G

Q

420

421

Q

R

A

G

D

W

K

C

P

N

P

T

C

E

N

M

N

F

S

W

R

N

E

C

N

Q

C

K

A

P

K

P

D

G

P

G

P

G

S

H

M

G

N

Y

G

D

R

G

R

G

Y

D

480

481

R

G

Y

R

G

R

G

D

R

G

F

R

G

R

G

D

R

G

F

G

P

G

K

M

D

S

R

G

E

H

R

Q

D

R

E

R

P

Y

526

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1399
Peptide:	YGQQSY
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P35637
UniProt Name:	FUS_HUMAN
Protein Name:	RNA-binding protein FUS
Position:	33-38

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	33.33
NuAPRpred:	-0.27
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-55.2
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	0.55
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

A

S

N

D

Y

T

Q

A

T

Q

S

Y

G

A

Y

P

T

Q

P

G

Q

G

Y

S

Q

S

Q

P

Y

G

Q

S

Y

S

G

Y

S

Q

S

T

D

T

S

G

Y

G

Q

S

Y

S

Y

G

Q

60

61

S

Q

N

T

G

Y

G

T

Q

S

T

P

Q

G

Y

G

S

T

G

Y

G

S

Q

S

Q

S

Y

G

Q

S

Y

P

G

Y

G

Q

P

A

P

S

T

S

G

S

Y

G

S

Q

S

120

121

S

Y

G

Q

P

Q

S

G

S

Y

S

Q

P

S

Y

G

Q

S

Y

G

Q

S

Y

N

P

Q

G

Y

G

Q

N

Q

Y

N

S

G

N

Y

G

Q

D

180

181

Q

S

M

S

G

S

G

Y

G

N

Q

D

Q

S

G

S

G

Y

G

Q

D

R

G

R

G

R

G

S

G

Y

N

R

S

G

Y

E

240

241

P

R

G

R

G

R

G

R

G

M

G

S

D

R

G

F

N

K

F

G

P

R

D

Q

G

S

R

H

D

S

E

Q

D

N

S

D

N

T

I

F

V

Q

G

L

G

E

N

V

T

I

E

S

300

301

V

A

D

Y

F

K

Q

I

G

I

K

T

N

K

T

G

Q

P

M

I

N

L

Y

T

D

R

E

T

G

K

L

K

G

E

A

T

V

S

F

D

P

S

A

K

A

I

D

W

F

D

G

K

E

F

S

360

361

G

N

P

I

K

V

S

F

A

T

R

A

D

F

N

R

G

N

G

R

G

R

G

R

G

P

M

G

R

G

Y

G

S

G

R

G

F

P

S

G

Q

420

421

Q

R

A

G

D

W

K

C

P

N

P

T

C

E

N

M

N

F

S

W

R

N

E

C

N

Q

C

K

A

P

K

P

D

G

P

G

P

G

S

H

M

G

N

Y

G

D

R

G

R

G

Y

D

480

481

R

G

Y

R

G

R

G

D

R

G

F

R

G

R

G

D

R

G

F

G

P

G

K

M

D

S

R

G

E

H

R

Q

D

R

E

R

P

Y

526

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1400
Peptide:	YGQSSY
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P35637
UniProt Name:	FUS_HUMAN
Protein Name:	RNA-binding protein FUS
Position:	50-55

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	33.33
NuAPRpred:	-0.35
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-36.4
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	0.43
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

Y

H

L

A

M

A

6

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1401
Peptide:	YHLAMA
Length:	6
Classification:	amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:
Protein Name:
Position:

Literature

PMID:	26440769
Reference:	Sci Rep. 2015 Oct 6;5:14794.
source:	Waltz-DB 2.0

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	83.33
NuAPRpred:	-0.04
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	18.4
Area of the profile Above Threshold (AGGRESCAN):	1.25
Best Energy Score (PASTA 2.0):	-0.79
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

S

L

C

V

R

V

K

R

A

K

F

Q

G

S

P

D

K

F

N

T

Y

V

T

L

K

V

Q

N

V

K

S

T

V

A

V

R

G

D

Q

P

S

W

E

Q

D

F

M

F

E

I

S

R

L

D

L

G

L

60

61

S

V

E

V

W

N

K

G

L

I

W

D

T

M

V

G

T

V

W

I

A

L

K

T

I

R

Q

S

D

E

G

P

G

E

W

S

T

L

E

A

E

T

L

M

K

D

E

I

C

G

T

R

N

P

T

P

H

K

120

121

I

L

D

T

R

F

E

L

P

F

D

I

P

E

A

R

Y

W

T

Y

K

W

E

Q

I

N

A

L

G

A

D

N

E

Y

S

Q

E

S

Q

R

K

P

L

P

T

A

Q

C

S

F

E

D

P

180

181

D

S

A

V

D

R

D

S

D

Y

R

S

E

T

S

N

S

F

P

Y

H

T

A

S

Q

P

N

A

S

V

H

Q

F

P

V

P

V

R

S

P

Q

L

Q

G

S

R

D

S

C

N

D

S

M

240

241

Q

S

Y

D

L

D

Y

P

E

R

A

I

S

P

T

S

R

Y

G

S

C

N

V

S

Q

G

S

Q

L

S

E

L

D

Q

Y

H

E

Q

D

H

R

E

T

D

S

I

H

S

C

H

S

H

300

301

S

L

S

R

D

G

Q

A

G

F

G

E

Q

E

K

P

L

E

V

T

G

Q

A

E

K

E

A

C

E

P

K

E

M

K

E

D

A

T

H

P

D

L

V

L

Q

K

D

H

F

L

G

P

Q

E

S

F

360

361

P

E

N

A

S

P

F

T

Q

A

R

A

H

W

I

R

A

V

T

K

V

R

L

Q

L

Q

E

I

P

D

G

D

P

S

L

P

Q

W

L

P

E

G

P

A

G

L

Y

G

I

D

S

M

P

D

L

R

420

421

R

K

P

L

P

L

V

S

D

L

S

L

V

Q

S

R

K

A

G

I

T

S

A

M

A

T

R

T

S

L

K

D

E

L

K

S

H

V

Y

K

T

L

Q

A

L

I

Y

P

I

S

C

T

P

H

N

F

480

481

E

V

W

T

A

T

P

T

Y

C

Y

E

C

E

G

L

W

G

I

A

R

Q

G

M

R

C

S

E

C

G

V

K

C

H

E

K

C

Q

D

L

N

A

D

C

L

Q

R

A

E

K

S

C

K

H

G

A

540

541

E

D

R

T

Q

N

I

M

A

M

K

D

R

M

K

I

R

E

R

N

K

P

E

I

F

E

V

I

R

D

V

F

T

V

N

K

A

H

V

Q

M

K

T

V

K

Q

S

V

L

D

G

T

S

K

W

S

A

600

601

K

I

T

I

T

V

C

A

Q

G

L

Q

A

K

D

K

T

G

S

D

P

Y

V

T

V

Q

V

S

K

T

K

R

T

K

T

I

F

G

N

L

N

P

V

W

E

K

F

H

F

E

C

H

N

S

D

660

661

R

I

K

V

R

V

W

D

E

D

I

K

S

R

V

K

Q

R

L

K

R

E

S

D

F

L

G

Q

T

I

E

V

R

T

L

S

G

E

M

D

V

W

Y

N

L

E

K

R

T

D

K

S

A

V

S

G

720

721

A

I

R

L

Q

I

S

V

E

I

K

G

E

K

V

A

P

Y

H

V

Q

Y

T

C

L

H

E

N

L

F

H

Y

L

T

D

I

Q

G

S

G

V

R

I

P

E

A

R

G

D

A

W

K

V

Y

F

D

E

780

781

T

A

Q

E

I

V

D

E

F

A

M

R

Y

G

I

E

S

I

Y

Q

A

M

T

H

F

A

C

L

S

K

Y

M

C

P

G

V

P

A

V

M

S

T

L

A

N

I

N

A

Y

A

H

T

A

S

T

N

840

841

V

S

A

S

D

R

F

A

S

N

F

G

K

E

R

F

V

K

L

D

Q

L

H

N

S

L

R

I

D

L

S

T

Y

R

N

F

P

A

G

S

P

E

R

L

Q

D

L

K

S

T

V

D

L

T

S

I

900

901

T

F

R

M

K

V

Q

E

L

Q

S

P

R

A

S

Q

V

K

D

C

V

K

A

C

L

N

S

T

Y

E

Y

I

F

N

C

H

D

L

Y

S

R

Q

Y

Q

L

K

Q

E

L

P

E

Q

G

P

960

961

S

I

R

N

L

D

F

W

P

K

L

I

T

L

I

V

S

I

E

D

K

N

S

Y

T

P

V

L

N

Q

F

P

Q

E

L

N

V

G

K

V

S

A

E

V

M

W

H

L

F

A

Q

D

M

K

Y

A

L

E

1020

1021

E

H

E

K

D

H

L

C

K

S

A

D

Y

M

N

L

H

F

K

V

K

W

L

H

N

E

Y

V

R

D

L

P

V

L

Q

G

Q

V

P

E

Y

P

A

W

F

E

Q

F

V

L

Q

W

L

D

E

N

E

D

V

S

1080

1081

L

E

F

L

R

G

A

L

E

R

D

K

D

G

F

Q

T

S

E

H

A

L

F

S

C

S

V

D

V

F

T

Q

L

N

Q

S

F

E

I

R

K

L

E

C

P

D

P

S

I

L

A

H

Y

M

R

1140

1141

F

A

K

T

I

G

K

V

L

M

Q

Y

A

D

I

L

S

K

D

F

P

A

Y

C

T

K

E

K

L

P

C

I

L

M

N

V

Q

L

R

V

Q

L

E

K

M

F

E

A

M

G

K

E

L

D

L

E

A

1200

1201

A

D

S

L

K

E

L

Q

V

K

L

N

T

V

L

D

E

L

S

M

V

F

G

N

S

F

Q

V

R

I

D

E

C

V

R

Q

M

A

D

I

L

G

Q

V

R

G

T

G

N

A

S

P

D

A

R

A

S

A

Q

1260

1261

D

A

D

S

V

L

R

P

L

M

D

F

L

D

G

N

L

T

L

F

A

T

V

C

E

K

T

V

L

K

R

V

L

K

E

L

W

R

V

M

N

T

M

E

R

M

I

V

L

P

L

T

D

Q

T

G

T

Q

1320

1321

L

I

F

T

A

K

E

L

S

H

L

S

K

L

K

D

H

M

V

R

E

T

R

N

L

T

P

K

Q

C

A

V

L

D

L

A

L

D

T

I

K

Q

Y

F

H

A

G

N

G

L

K

T

F

L

E

K

1380

1381

S

P

D

L

Q

S

L

R

Y

A

L

S

L

Y

T

Q

T

D

T

L

I

K

T

F

V

R

S

Q

T

Q

G

S

G

V

D

P

V

G

E

V

S

I

Q

V

D

L

F

T

H

P

G

T

G

E

H

K

V

1440

1441

T

V

K

V

A

N

D

L

K

W

Q

T

A

G

M

F

R

P

F

V

E

V

T

M

V

G

P

H

Q

S

D

K

R

K

F

T

K

S

K

S

N

W

A

P

K

Y

N

E

T

F

H

F

L

G

1500

1501

N

E

G

P

E

S

Y

E

L

Q

I

C

V

K

D

Y

C

F

A

R

E

D

R

V

L

G

L

A

V

M

P

L

R

D

V

T

A

K

G

S

C

A

C

W

C

P

L

G

R

K

I

H

M

D

E

T

G

L

T

1560

1561

I

L

R

I

L

S

Q

R

S

N

D

E

V

A

R

E

F

V

K

L

K

S

E

S

R

S

T

E

G

S

1591

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1402
Peptide:	YIFNNC
Length:	6
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	O14795
UniProt Name:	UN13B_HUMAN
Protein Name:	Protein unc-13 homolog B (Munc13-2) (munc13)
Position:	934-939

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	66.67
NuAPRpred:	0.96
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	15.5
Area of the profile Above Threshold (AGGRESCAN):	1.74
Best Energy Score (PASTA 2.0):	-3.32
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

K

L

S

R

Q

F

T

V

F

G

S

A

I

F

C

V

I

F

S

L

Y

L

M

L

D

R

G

H

L

D

Y

P

R

N

P

R

E

G

S

F

P

Q

G

Q

L

S

M

L

Q

E

K

I

D

H

L

E

R

60

61

L

A

E

N

E

I

S

N

I

R

D

S

V

I

N

L

S

E

S

V

E

D

G

P

K

S

Q

S

N

F

S

Q

G

A

G

S

H

L

P

S

Q

L

S

L

S

V

D

T

A

D

C

L

F

A

S

120

121

Q

S

G

S

H

N

S

D

V

Q

M

L

D

V

Y

S

L

I

S

F

D

N

P

D

G

V

W

K

Q

G

F

D

I

T

Y

E

S

N

E

W

D

T

E

P

L

Q

V

F

V

P

H

S

H

N

D

P

G

W

180

181

L

K

T

F

N

D

Y

F

R

D

K

T

Q

Y

I

F

N

M

V

L

K

L

K

E

D

S

R

K

F

I

W

S

E

I

S

Y

L

S

K

W

D

I

D

I

Q

K

D

A

V

K

S

L

I

E

N

240

241

G

Q

L

E

I

V

T

G

W

V

M

P

D

E

A

T

P

H

Y

F

A

L

I

D

Q

L

I

E

G

H

Q

W

L

E

N

I

G

V

K

P

R

S

G

W

A

I

D

P

F

G

H

S

P

T

M

A

Y

L

300

301

L

N

R

A

G

L

S

H

M

L

I

Q

R

V

H

Y

A

V

K

H

F

A

L

H

K

T

L

E

F

W

R

Q

N

W

D

L

G

S

V

T

D

I

L

C

H

M

P

F

Y

S

Y

D

I

P

H

T

C

360

361

G

P

D

P

K

I

C

Q

F

D

F

K

R

L

P

G

R

F

G

C

P

W

G

V

P

E

T

I

H

P

G

N

V

Q

S

R

A

R

M

L

D

Q

Y

R

K

S

K

L

F

R

T

K

V

L

420

421

A

P

L

G

D

F

R

Y

C

E

Y

T

E

W

D

L

Q

F

K

N

Y

Q

L

F

D

Y

M

N

S

Q

S

K

F

K

V

K

I

Q

F

G

T

L

S

D

F

D

A

L

D

K

A

D

E

T

Q

R

D

480

481

K

G

Q

S

M

F

P

V

L

S

G

D

F

T

Y

A

D

R

D

H

Y

W

S

G

Y

F

T

S

R

P

F

Y

K

R

M

D

R

I

M

E

S

H

L

R

A

E

I

L

Y

F

A

L

R

Q

A

H

540

541

K

Y

K

I

N

K

F

L

S

L

Y

T

A

L

T

E

A

R

N

L

G

L

F

Q

H

D

A

I

T

G

T

A

K

D

W

V

D

Y

G

T

R

L

F

H

S

L

M

V

L

E

K

I

G

600

601

N

S

A

F

L

I

L

K

D

K

L

T

Y

D

S

Y

S

P

D

T

F

L

E

M

D

L

K

Q

K

S

Q

D

S

L

P

Q

K

N

I

R

L

S

A

E

P

R

Y

L

V

Y

N

P

L

E

Q

D

R

660

661

I

S

L

V

S

V

Y

V

S

P

T

V

Q

V

F

S

A

S

G

K

P

V

E

V

Q

V

S

A

V

W

D

T

A

N

T

I

S

E

T

A

Y

E

I

S

F

R

A

H

I

P

L

G

L

K

V

Y

K

I

720

721

L

E

S

A

S

N

S

H

L

A

D

Y

V

L

Y

K

N

K

V

E

D

S

G

I

F

T

I

K

N

M

I

N

T

E

G

I

T

L

E

N

S

F

V

L

R

F

D

Q

T

G

L

M

K

Q

M

T

780

781

K

E

D

G

K

H

E

V

N

V

Q

F

S

W

Y

G

T

I

K

R

D

K

S

G

A

Y

L

F

L

P

D

G

N

A

K

P

Y

V

Y

T

P

F

V

R

V

T

H

G

R

I

Y

S

E

V

T

C

840

841

F

D

H

V

T

H

R

V

R

L

Y

H

I

Q

G

I

E

G

Q

S

V

E

V

S

N

I

V

D

I

R

K

V

Y

N

R

E

I

A

M

K

I

S

D

I

K

S

Q

N

R

F

Y

T

D

L

N

G

Y

Q

900

901

I

Q

P

R

M

T

L

S

K

L

P

L

Q

A

N

V

Y

P

M

T

M

A

Y

I

Q

D

A

K

H

R

L

T

L

S

A

Q

S

L

G

V

S

L

N

S

G

Q

I

E

V

I

M

D

R

L

M

Q

960

961

D

N

R

G

L

E

Q

G

I

Q

D

N

K

I

T

A

N

L

F

R

I

L

E

K

R

S

A

V

N

T

E

K

S

V

S

Y

P

S

L

S

H

I

T

S

L

M

N

H

P

V

I

P

M

1020

1021

A

N

K

F

S

P

T

L

E

L

Q

G

E

F

S

P

L

Q

S

L

P

C

D

I

H

L

V

N

L

R

T

I

Q

S

K

V

G

N

G

H

S

N

E

A

L

I

L

H

R

K

G

F

D

C

R

F

S

1080

1081

S

K

G

T

G

L

F

C

S

T

Q

G

K

I

L

V

Q

K

L

N

K

F

I

V

E

S

L

T

P

S

L

S

L

M

H

S

P

G

T

Q

N

I

S

E

I

N

L

S

P

M

E

I

S

T

F

R

1140

1141

I

Q

L

R

1144

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1403
Peptide:	YIFNNM
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	Q16706
UniProt Name:	MA2A1_HUMAN
Protein Name:	Alpha-mannosidase 2
Position:	194-199

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	66.67
NuAPRpred:	0.6
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	18.6
Area of the profile Above Threshold (AGGRESCAN):	1.8
Best Energy Score (PASTA 2.0):	-3.43
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

S

D

S

N

Q

G

N

Q

N

Y

Q

Y

S

Q

N

G

N

Q

G

N

R

Y

Q

G

Y

Q

A

Y

N

A

Q

A

Q

P

A

G

Y

Q

N

Y

Q

G

Y

S

G

Y

Q

G

Y

60

61

Q

Y

N

P

D

A

G

Y

Q

Y

N

P

Q

G

Y

Q

Y

N

P

Q

G

Y

Q

F

N

P

Q

G

R

G

N

Y

K

N

F

N

Y

N

L

Q

G

Y

Q

A

G

F

Q

P

Q

120

121

S

Q

G

M

S

L

N

D

F

Q

K

Q

K

Q

A

P

K

P

K

T

L

K

L

V

S

G

I

K

L

A

N

A

T

K

V

G

T

K

P

A

E

S

D

K

E

K

S

A

E

T

K

180

181

E

P

T

K

E

P

T

K

V

E

P

V

K

E

K

P

V

Q

T

E

K

T

E

K

S

E

L

P

K

V

E

D

L

K

I

S

E

S

T

H

N

T

N

A

N

V

T

S

A

D

A

L

I

K

240

241

E

Q

E

V

D

E

V

N

D

M

F

G

K

D

H

V

S

L

I

F

M

G

H

V

D

A

G

K

S

T

M

G

N

L

Y

L

T

G

S

V

D

K

R

T

I

E

K

Y

E

R

E

A

K

300

301

D

A

G

R

Q

G

W

Y

L

S

W

V

M

D

T

N

K

E

R

N

D

G

K

T

I

E

V

G

K

A

Y

F

E

T

E

K

R

Y

T

I

L

D

A

P

G

H

K

M

Y

V

S

E

M

I

G

A

S

360

361

Q

A

D

V

G

V

L

V

I

S

A

R

K

G

E

Y

E

T

G

F

E

R

G

Q

T

R

E

H

A

L

A

K

T

Q

G

V

N

K

M

V

N

K

M

D

P

T

V

N

W

S

K

E

R

Y

420

421

D

Q

C

V

S

N

V

S

N

F

L

R

A

I

G

Y

N

I

K

T

D

V

F

M

P

V

S

G

Y

S

G

A

N

L

K

D

H

V

D

P

K

E

C

P

W

Y

T

G

P

T

L

E

Y

L

D

T

M

N

480

481

H

V

D

R

H

I

N

A

P

F

M

L

P

I

A

K

M

K

D

L

G

T

I

V

E

G

K

I

E

S

G

H

I

K

G

Q

S

T

L

M

P

N

K

T

A

V

E

I

Q

N

I

Y

N

E

T

E

N

540

541

E

V

D

M

A

M

C

G

E

Q

V

K

L

R

I

K

G

V

E

D

I

S

P

G

F

V

L

T

S

P

K

N

P

I

K

S

V

T

K

F

V

A

Q

I

A

I

V

E

L

K

S

I

A

G

F

S

600

601

C

V

M

H

V

H

T

A

I

E

V

H

I

V

K

L

H

K

L

E

K

G

T

N

R

K

S

K

P

A

F

A

K

G

M

K

V

I

A

V

L

E

T

E

A

P

V

C

V

E

T

Y

Q

D

Y

660

661

P

Q

L

G

R

F

T

L

R

D

Q

G

T

I

A

I

G

K

I

V

K

I

A

E

685

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1404
Peptide:	YKNFNY
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P05453
UniProt Name:	ERF3_YEAST
Protein Name:	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)
Position:	101-106

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	1
Absolute Charge:	1
Hydrophobicity:	50.0
NuAPRpred:	0.14
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-15.6
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	-1.28
Aggregate Orientation (PASTA 2.0):	Parallel

Peptide details

Entry:	P-1405
Peptide:	YLEIII
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:
Protein Name:
Position:

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	CPAD, Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	-1
Absolute Charge:	1
Hydrophobicity:	83.33
NuAPRpred:	1.06
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	62.6
Area of the profile Above Threshold (AGGRESCAN):	4.02
Best Energy Score (PASTA 2.0):	-4.49
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

H

T

C

P

V

T

L

E

Q

D

L

H

R

K

M

H

S

W

M

L

Q

T

L

A

F

A

V

T

S

L

V

L

S

C

A

E

T

I

D

Y

G

E

I

C

D

N

A

C

P

C

E

K

D

G

I

60

61

L

T

V

S

C

E

N

R

G

I

S

L

S

E

I

S

P

R

F

P

I

Y

H

L

S

G

N

L

N

R

L

Y

P

N

E

F

V

N

Y

T

G

A

S

I

L

H

L

G

S

N

V

I

Q

D

I

120

121

E

T

G

A

F

H

G

L

R

G

L

R

L

H

L

N

K

L

E

L

R

D

T

F

L

G

L

E

N

L

E

Y

L

Q

V

D

Y

N

Y

I

S

V

I

E

P

N

A

F

G

K

L

H

L

Q

180

181

V

L

I

L

N

D

N

L

S

L

P

N

L

F

R

F

V

P

L

T

H

L

D

L

R

G

N

R

L

K

L

P

Y

V

G

L

Q

H

M

D

K

V

E

L

Q

L

E

N

P

W

N

C

S

240

241

C

E

L

I

S

L

K

D

W

L

D

S

I

S

Y

S

A

L

V

G

D

V

C

E

T

P

F

R

L

H

G

R

D

L

D

E

V

S

K

Q

E

L

C

P

R

L

I

S

D

Y

E

M

R

P

Q

T

P

L

300

301

S

T

G

Y

L

H

T

P

A

S

V

N

S

V

A

T

S

A

V

Y

K

P

L

K

P

K

G

T

R

Q

P

N

K

P

R

V

R

P

T

S

R

Q

P

S

K

D

L

G

Y

S

N

Y

G

P

360

361

S

I

A

Y

Q

T

K

S

P

V

P

L

E

C

P

T

A

C

S

C

N

L

Q

I

S

D

L

G

L

N

V

N

C

Q

E

R

K

I

E

S

I

A

E

L

Q

P

K

P

Y

N

P

K

M

Y

L

T

E

N

Y

420

421

I

A

V

R

T

D

F

L

E

A

T

G

L

D

L

H

L

G

N

R

I

S

M

I

Q

D

R

A

F

G

D

L

T

N

L

R

L

Y

L

N

G

N

R

I

E

R

L

S

P

E

L

F

Y

G

L

480

481

Q

S

L

Q

Y

L

F

L

Q

Y

N

L

I

R

E

I

Q

S

G

T

F

D

P

V

P

N

L

Q

L

F

L

N

L

Q

A

M

P

S

G

V

F

S

G

L

T

L

R

L

N

L

R

S

N

H

F

540

541

T

S

L

P

V

S

G

V

L

D

Q

L

K

S

L

I

Q

I

D

L

H

D

N

P

W

D

C

T

C

D

I

V

G

M

K

L

W

V

E

Q

L

K

V

G

V

L

V

D

E

V

I

C

K

A

P

K

F

A

E

600

601

T

D

M

R

S

I

K

S

E

L

C

P

D

Y

S

D

V

S

T

P

T

P

S

I

Q

V

P

A

R

T

S

A

V

T

P

A

V

R

L

N

S

T

G

A

P

A

S

L

G

A

G

A

S

660

661

V

P

L

S

V

L

I

L

S

L

V

F

I

M

S

V

F

V

A

G

L

F

V

L

V

M

K

R

K

N

Q

S

D

H

T

S

T

N

S

D

V

S

F

N

M

Q

Y

S

V

Y

G

720

721

G

T

G

H

P

H

A

H

V

H

R

G

P

A

L

P

K

V

K

T

P

A

G

H

V

Y

E

Y

I

P

H

P

L

G

H

M

C

K

N

P

I

Y

R

S

R

E

G

N

S

V

E

D

Y

K

D

L

H

780

781

E

L

K

V

T

Y

S

N

H

L

Q

P

Q

P

Q

P

Q

L

Q

L

Q

P

G

E

R

E

S

H

L

R

S

P

A

Y

S

V

S

T

I

E

P

840

841

R

E

D

L

S

P

V

Q

D

A

D

R

F

Y

R

G

I

L

E

P

D

K

H

C

S

T

P

A

G

N

S

L

P

E

Y

P

K

F

P

C

S

P

A

Y

T

F

S

P

N

Y

D

L

R

P

H

Q

900

901

Y

L

H

P

G

A

G

D

S

R

L

R

E

P

V

L

Y

S

P

S

A

V

F

V

E

P

N

R

N

E

Y

L

E

L

K

A

K

L

N

V

E

P

D

Y

L

E

V

L

E

K

Q

T

F

S

Q

F

958

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1406
Peptide:	YLFLQY
Length:	6
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	O94991
UniProt Name:	SLIK5_HUMAN
Protein Name:	SLIT and NTRK-like protein 5 (Leucine-rich repeat-containing protein 11)
Position:	485-490

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	83.33
NuAPRpred:	0.87
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	69.8
Area of the profile Above Threshold (AGGRESCAN):	4.72
Best Energy Score (PASTA 2.0):	-2.84
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

D

T

D

K

L

I

S

E

A

E

S

H

F

S

Q

G

N

H

A

E

A

V

A

K

L

T

S

A

Q

S

N

P

N

D

E

Q

M

S

T

I

E

S

L

I

Q

K

I

A

G

Y

V

M

D

N

R

S

G

60

61

S

D

A

S

Q

D

R

A

G

S

F

M

N

T

L

M

A

D

S

K

G

S

Q

T

Q

L

G

K

L

A

L

A

T

V

M

T

H

S

N

K

G

S

N

R

G

F

D

V

G

T

V

M

120

121

S

M

L

S

G

S

G

S

Q

S

M

G

A

S

G

L

A

L

A

S

Q

F

K

S

G

N

S

Q

G

Q

G

Q

G

Q

G

Q

G

Q

G

Q

G

Q

G

Q

G

Q

G

S

F

T

A

L

A

S

L

180

181

A

S

F

M

N

S

N

Q

G

Q

N

Q

S

G

S

F

G

A

L

A

S

M

A

S

F

M

H

S

N

Q

N

S

N

S

Q

G

Y

N

Q

S

Y

Q

N

G

N

Q

N

240

241

S

Q

G

Y

N

Q

Y

Q

G

N

G

Y

Q

G

Q

S

G

A

F

S

L

A

S

M

A

Q

S

Y

L

G

Q

T

Q

S

N

Q

Y

N

Q

G

Q

N

Q

300

301

Y

Q

G

Q

N

Y

Q

H

Q

G

Q

G

H

S

F

S

A

L

A

S

M

A

S

Y

L

G

N

S

N

S

N

S

Y

G

Q

A

N

E

Y

G

R

P

Q

360

361

N

G

Q

S

N

E

Y

G

R

P

Q

Y

G

N

Q

N

S

N

G

Q

H

E

S

F

N

F

S

G

N

F

S

Q

N

G

N

Q

N

R

Y

405

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1407
Peptide:	YLGNNS
Length:	6
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P25367
UniProt Name:	RNQ1_YEAST
Protein Name:	[PIN+] prion protein RNQ1
Position:	335-340

Literature

PMID:	SwitchLab
Reference:	Switch Lab
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	33.33
NuAPRpred:	-0.27
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-45.1
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	0.17
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

Y

L

W

Y

C

6

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1408
Peptide:	YLLWYC
Length:	6
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P04004
UniProt Name:	VTNC_HUMAN
Protein Name:	Vitronectin (VN) (S-protein) (Serum-spreading factor)
Position:

Literature

PMID:	23815227
Reference:	BMC Bioinformatics. 2013;14 Suppl 8:S6.
source:	CPAD, Waltz-DB 2.0

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	100.0
NuAPRpred:	1.04
Tango:	47.68

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	81.8
Area of the profile Above Threshold (AGGRESCAN):	5.37
Best Energy Score (PASTA 2.0):	-3.35
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

S

R

S

V

A

L

A

V

L

A

L

S

L

S

G

L

E

A

I

Q

R

T

P

K

I

Q

V

Y

S

R

H

P

A

E

N

G

K

S

N

F

L

N

C

Y

V

S

G

F

H

P

S

D

I

E

V

D

L

60

61

K

N

G

E

R

I

E

K

V

E

H

S

D

L

S

F

S

K

D

W

S

F

Y

L

Y

T

E

F

T

P

T

E

K

D

E

Y

A

C

R

V

N

H

V

T

L

S

Q

P

K

I

V

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119

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1409
Peptide:	YLLYYT
Length:	6
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P61769
UniProt Name:	B2MG_HUMAN
Protein Name:	Beta-2-microglobulin
Position:	83-88

Literature

PMID:	14691246
Reference:	Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):87-92.
source:	Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	83.33
NuAPRpred:	0.81
Tango:	11.63

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	76.6
Area of the profile Above Threshold (AGGRESCAN):	5.07
Best Energy Score (PASTA 2.0):	-2.9
Aggregate Orientation (PASTA 2.0):	Parallel

Peptide details

Entry:	P-1410
Peptide:	YLNWYQ
Length:	6
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:
Protein Name:
Position:

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	CPAD, Waltz-DB 2.0, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	66.67
NuAPRpred:	0.74
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	9.8
Area of the profile Above Threshold (AGGRESCAN):	1.31
Best Energy Score (PASTA 2.0):	-2.5
Aggregate Orientation (PASTA 2.0):	Parallel

Database of known aggregating/non-aggregating peptides

Displaying 1381 to 1410 records out of 2031 records fetched.