CPAD 2.0

Entry	Peptide	Length	Class	Protein Name	UniProt ID	Mutant	Reference	PMID	Source Database
P-1591	GNNQQNYQQY	10	Amyloid	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)	P05453	No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	CPAD, AmyLoad
P-1592	GSAMSRPIIH	10	Non-amyloid	Major prion protein (PrP)	P04156	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad
P-1593	GTDFKYKGKL	10	Non-amyloid	Myohemerythrin (MHr)	P02247	No	J Mol Biol. 1992 Aug 5;226(3):795-817.	1507227	AmyLoad
P-1594	GYLTVAAVFR	10	Amyloid				Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4074-8.	16537487	CPAD, AmyLoad
P-1595	HMAGAAAAGA	10	Non-amyloid	Major prion protein (PrP)	P04156	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad
P-1596	HPAENGKSNF	10	Non-amyloid	Beta-2-microglobulin	P61769	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad
P-1597	HSQWNKPSKP	10	Non-amyloid	Major prion protein (PrP)	P04156	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad
P-1598	ILLISFLIFL	10	Amyloid	Major prion protein (PrP)	P04156	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad
P-1599	IVAGVNYFLD	10	Amyloid	Cystatin-C	P01034	No	J Struct Biol. 2015 Sep;191(3):272-80.	26235923	AmyLoad
P-1600	KDWSFYLLYY	10	Amyloid	Beta-2-microglobulin	P61769	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	CPAD, AmyLoad
P-1601	KEPTKVEEPV	10	Non-amyloid	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)	P05453	No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	AmyLoad
P-1602	KLVSSSGIKL	10	Non-amyloid	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)	P05453	No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	AmyLoad
P-1603	KNNAGFPHNV	10	Non-amyloid	Plastocyanin	P00287	No	J Mol Biol. 1992 Aug 5;226(3):819-35.	1507228	AmyLoad
P-1604	KPKKTLKLVS	10	Non-amyloid	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)	P05453	No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	AmyLoad
P-1605	KPSKPKTNMK	10	Non-amyloid	Major prion protein (PrP)	P04156	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad
P-1606	KSAETKEPTK	10	Non-amyloid	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)	P05453	No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	AmyLoad
P-1607	KTEEKSELPK	10	Non-amyloid	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)	P05453	No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	AmyLoad
P-1608	KTLKLVSSSG	10	Non-amyloid	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)	P05453	No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	AmyLoad
P-1609	KTNMKHMAGA	10	Non-amyloid	Major prion protein (PrP)	P04156	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad
P-1610	KVEHSDLSFS	10	Non-amyloid	Beta-2-microglobulin	P61769	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad
P-1611	KVGTKPAESD	10	Non-amyloid	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)	P05453	No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	AmyLoad
P-1612	KYLLFCMENS	10	Amyloid	Beta-lactoglobulin (Beta-LG)	P02755	No	J Mol Biol. 2009 Feb 27;386(3):878-90.	19133274	CPAD
P-1613	LANATKKVGT	10	Non-amyloid	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)	P05453	No	Nat Methods. 2010 Mar;7(3):237-42.	20154676	AmyLoad
P-1614	LANWMCLAKW	10	Amyloid	Lysozyme C	P61626	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	CPAD, AmyLoad
P-1615	LGMDGYRGIS	10	Non-amyloid	Lysozyme C	P61626	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad
P-1616	LNCYVSGFHP	10	Non-amyloid	Beta-2-microglobulin	P61769	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad
P-1617	LQDNIADAVA	10	Non-amyloid	Lysozyme C	P61626	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad
P-1618	MDEYSNQNNF	10	Non-amyloid	Major prion protein (PrP)	P04156	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad
P-1619	MERVVEQMCI	10	Non-amyloid	Major prion protein (PrP)	P04156	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad
P-1620	NACHLSCSAL	10	Non-amyloid	Lysozyme C	P61626	No	Nat Biotechnol. 2004 Oct;22(10):1302-6.	15361882	AmyLoad

Sequence

1

M

S

D

S

N

Q

G

N

Q

N

Y

Q

Y

S

Q

N

G

N

Q

G

N

R

Y

Q

G

Y

Q

A

Y

N

A

Q

A

Q

P

A

G

Y

Q

N

Y

Q

G

Y

S

G

Y

Q

G

Y

60

61

Q

Y

N

P

D

A

G

Y

Q

Y

N

P

Q

G

Y

Q

Y

N

P

Q

G

Y

Q

F

N

P

Q

G

R

G

N

Y

K

N

F

N

Y

N

L

Q

G

Y

Q

A

G

F

Q

P

Q

120

121

S

Q

G

M

S

L

N

D

F

Q

K

Q

K

Q

A

P

K

P

K

T

L

K

L

V

S

G

I

K

L

A

N

A

T

K

V

G

T

K

P

A

E

S

D

K

E

K

S

A

E

T

K

180

181

E

P

T

K

E

P

T

K

V

E

P

V

K

E

K

P

V

Q

T

E

K

T

E

K

S

E

L

P

K

V

E

D

L

K

I

S

E

S

T

H

N

T

N

A

N

V

T

S

A

D

A

L

I

K

240

241

E

Q

E

V

D

E

V

N

D

M

F

G

K

D

H

V

S

L

I

F

M

G

H

V

D

A

G

K

S

T

M

G

N

L

Y

L

T

G

S

V

D

K

R

T

I

E

K

Y

E

R

E

A

K

300

301

D

A

G

R

Q

G

W

Y

L

S

W

V

M

D

T

N

K

E

R

N

D

G

K

T

I

E

V

G

K

A

Y

F

E

T

E

K

R

Y

T

I

L

D

A

P

G

H

K

M

Y

V

S

E

M

I

G

A

S

360

361

Q

A

D

V

G

V

L

V

I

S

A

R

K

G

E

Y

E

T

G

F

E

R

G

Q

T

R

E

H

A

L

A

K

T

Q

G

V

N

K

M

V

N

K

M

D

P

T

V

N

W

S

K

E

R

Y

420

421

D

Q

C

V

S

N

V

S

N

F

L

R

A

I

G

Y

N

I

K

T

D

V

F

M

P

V

S

G

Y

S

G

A

N

L

K

D

H

V

D

P

K

E

C

P

W

Y

T

G

P

T

L

E

Y

L

D

T

M

N

480

481

H

V

D

R

H

I

N

A

P

F

M

L

P

I

A

K

M

K

D

L

G

T

I

V

E

G

K

I

E

S

G

H

I

K

G

Q

S

T

L

M

P

N

K

T

A

V

E

I

Q

N

I

Y

N

E

T

E

N

540

541

E

V

D

M

A

M

C

G

E

Q

V

K

L

R

I

K

G

V

E

D

I

S

P

G

F

V

L

T

S

P

K

N

P

I

K

S

V

T

K

F

V

A

Q

I

A

I

V

E

L

K

S

I

A

G

F

S

600

601

C

V

M

H

V

H

T

A

I

E

V

H

I

V

K

L

H

K

L

E

K

G

T

N

R

K

S

K

P

A

F

A

K

G

M

K

V

I

A

V

L

E

T

E

A

P

V

C

V

E

T

Y

Q

D

Y

660

661

P

Q

L

G

R

F

T

L

R

D

Q

G

T

I

A

I

G

K

I

V

K

I

A

E

685

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1591
Peptide:	GNNQQNYQQY
Length:	10
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P05453
UniProt Name:	ERF3_YEAST
Protein Name:	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)
Position:	7-16

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	CPAD, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	20.0
NuAPRpred:	-0.63
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-78.9
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	-1.09
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

A

N

L

G

C

W

M

L

V

L

F

V

A

T

W

S

D

L

G

L

C

K

R

P

K

P

G

W

N

T

G

S

R

Y

P

G

Q

G

S

P

G

N

R

Y

P

Q

G

W

G

Q

P

60

61

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

G

T

H

S

Q

W

N

K

P

S

K

P

K

T

N

M

K

H

M

A

G

A

G

A

120

121

V

G

L

G

Y

M

L

G

S

A

M

S

R

P

I

H

F

G

S

D

Y

E

D

R

Y

R

E

N

M

H

R

Y

P

N

Q

V

Y

R

P

M

D

E

Y

S

N

Q

N

F

V

H

D

C

V

180

181

N

I

T

I

K

Q

H

T

V

T

K

G

E

N

F

T

E

T

D

V

K

M

E

R

V

E

Q

M

C

I

T

Q

Y

E

R

E

S

Q

A

Y

Q

R

G

S

M

V

L

F

S

P

V

240

241

I

L

I

S

F

L

I

F

L

I

V

G

253

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1592
Peptide:	GSAMSRPIIH
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P04156
UniProt Name:	PRIO_HUMAN
Protein Name:	Major prion protein (PrP)
Position:	131-140

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	1
Absolute Charge:	1
Hydrophobicity:	50.0
NuAPRpred:	-2.69
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	1.4
Area of the profile Above Threshold (AGGRESCAN):	0.94
Best Energy Score (PASTA 2.0):	0.16
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

G

W

E

I

P

E

P

Y

V

W

D

E

S

F

R

V

F

Y

E

Q

L

D

E

H

K

I

F

K

G

I

F

D

C

I

R

D

N

S

A

P

N

L

A

T

L

V

K

V

T

N

H

F

T

H

E

A

60

61

M

D

A

K

Y

S

E

V

P

H

K

M

H

K

D

F

L

E

K

I

G

L

S

A

P

V

D

A

K

N

V

D

Y

C

K

E

W

L

V

N

H

I

K

G

T

D

F

K

Y

K

G

K

L

118

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1593
Peptide:	GTDFKYKGKL
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P02247
UniProt Name:	HEMTM_THEHE
Protein Name:	Myohemerythrin (MHr)
Position:	109-118

Literature

PMID:	1507227
Reference:	J Mol Biol. 1992 Aug 5;226(3):795-817.
source:	AmyLoad

Derived Information

Net Charge:	2
Absolute Charge:	4
Hydrophobicity:	30.0
NuAPRpred:	-1.76
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-26.0
Area of the profile Above Threshold (AGGRESCAN):	0.19
Best Energy Score (PASTA 2.0):	-0.64
Aggregate Orientation (PASTA 2.0):	Antiparallel

Peptide details

Entry:	P-1594
Peptide:	GYLTVAAVFR
Length:	10
Classification:	Amyloid
Mutation(s):
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:
Protein Name:
Position:

Literature

PMID:	16537487
Reference:	Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4074-8.
source:	CPAD, AmyLoad

Derived Information

Net Charge:	1
Absolute Charge:	1
Hydrophobicity:	70.0
NuAPRpred:	1.19
Tango:	760.52

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	44.8
Area of the profile Above Threshold (AGGRESCAN):	4.71
Best Energy Score (PASTA 2.0):	-5.17
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

A

N

L

G

C

W

M

L

V

L

F

V

A

T

W

S

D

L

G

L

C

K

R

P

K

P

G

W

N

T

G

S

R

Y

P

G

Q

G

S

P

G

N

R

Y

P

Q

G

W

G

Q

P

60

61

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

G

T

H

S

Q

W

N

K

P

S

K

P

K

T

N

M

K

H

M

A

G

A

G

A

120

121

V

G

L

G

Y

M

L

G

S

A

M

S

R

P

I

H

F

G

S

D

Y

E

D

R

Y

R

E

N

M

H

R

Y

P

N

Q

V

Y

R

P

M

D

E

Y

S

N

Q

N

F

V

H

D

C

V

180

181

N

I

T

I

K

Q

H

T

V

T

K

G

E

N

F

T

E

T

D

V

K

M

E

R

V

E

Q

M

C

I

T

Q

Y

E

R

E

S

Q

A

Y

Q

R

G

S

M

V

L

F

S

P

V

240

241

I

L

I

S

F

L

I

F

L

I

V

G

253

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1595
Peptide:	HMAGAAAAGA
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P04156
UniProt Name:	PRIO_HUMAN
Protein Name:	Major prion protein (PrP)
Position:	111-120

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	70.0
NuAPRpred:	-1.6
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-22.5
Area of the profile Above Threshold (AGGRESCAN):	0.07
Best Energy Score (PASTA 2.0):	1.74
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

S

R

S

V

A

L

A

V

L

A

L

S

L

S

G

L

E

A

I

Q

R

T

P

K

I

Q

V

Y

S

R

H

P

A

E

N

G

K

S

N

F

L

N

C

Y

V

S

G

F

H

P

S

D

I

E

V

D

L

60

61

K

N

G

E

R

I

E

K

V

E

H

S

D

L

S

F

S

K

D

W

S

F

Y

L

Y

T

E

F

T

P

T

E

K

D

E

Y

A

C

R

V

N

H

V

T

L

S

Q

P

K

I

V

K

W

D

R

D

M

119

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1596
Peptide:	HPAENGKSNF
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P61769
UniProt Name:	B2MG_HUMAN
Protein Name:	Beta-2-microglobulin
Position:	33-42

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	2
Hydrophobicity:	30.0
NuAPRpred:	-2.84
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-69.4
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	1.14
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

A

N

L

G

C

W

M

L

V

L

F

V

A

T

W

S

D

L

G

L

C

K

R

P

K

P

G

W

N

T

G

S

R

Y

P

G

Q

G

S

P

G

N

R

Y

P

Q

G

W

G

Q

P

60

61

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

G

T

H

S

Q

W

N

K

P

S

K

P

K

T

N

M

K

H

M

A

G

A

G

A

120

121

V

G

L

G

Y

M

L

G

S

A

M

S

R

P

I

H

F

G

S

D

Y

E

D

R

Y

R

E

N

M

H

R

Y

P

N

Q

V

Y

R

P

M

D

E

Y

S

N

Q

N

F

V

H

D

C

V

180

181

N

I

T

I

K

Q

H

T

V

T

K

G

E

N

F

T

E

T

D

V

K

M

E

R

V

E

Q

M

C

I

T

Q

Y

E

R

E

S

Q

A

Y

Q

R

G

S

M

V

L

F

S

P

V

240

241

I

L

I

S

F

L

I

F

L

I

V

G

253

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1597
Peptide:	HSQWNKPSKP
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P04156
UniProt Name:	PRIO_HUMAN
Protein Name:	Major prion protein (PrP)
Position:	96-105

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	2
Absolute Charge:	2
Hydrophobicity:	30.0
NuAPRpred:	-2.56
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-58.0
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	0.22
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

A

N

L

G

C

W

M

L

V

L

F

V

A

T

W

S

D

L

G

L

C

K

R

P

K

P

G

W

N

T

G

S

R

Y

P

G

Q

G

S

P

G

N

R

Y

P

Q

G

W

G

Q

P

60

61

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

G

T

H

S

Q

W

N

K

P

S

K

P

K

T

N

M

K

H

M

A

G

A

G

A

120

121

V

G

L

G

Y

M

L

G

S

A

M

S

R

P

I

H

F

G

S

D

Y

E

D

R

Y

R

E

N

M

H

R

Y

P

N

Q

V

Y

R

P

M

D

E

Y

S

N

Q

N

F

V

H

D

C

V

180

181

N

I

T

I

K

Q

H

T

V

T

K

G

E

N

F

T

E

T

D

V

K

M

E

R

V

E

Q

M

C

I

T

Q

Y

E

R

E

S

Q

A

Y

Q

R

G

S

M

V

L

F

S

P

V

240

241

I

L

I

S

F

L

I

F

L

I

V

G

253

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1598
Peptide:	ILLISFLIFL
Length:	10
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P04156
UniProt Name:	PRIO_HUMAN
Protein Name:	Major prion protein (PrP)
Position:	241-250

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	90.0
NuAPRpred:	5.19
Tango:	804.18

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	118.5
Area of the profile Above Threshold (AGGRESCAN):	12.54
Best Energy Score (PASTA 2.0):	-10.06
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

A

G

P

L

R

A

P

L

A

I

L

A

V

A

L

A

V

S

P

A

G

S

P

G

K

P

R

L

V

G

P

M

D

A

S

V

E

G

V

R

A

L

D

F

A

V

G

E

Y

60

61

N

K

A

S

N

D

M

Y

H

S

R

A

L

Q

V

R

A

R

K

Q

I

V

A

G

V

N

Y

F

L

D

V

E

L

G

R

T

C

T

K

T

Q

P

N

L

D

N

C

P

F

H

D

Q

P

H

L

K

R

K

120

121

A

F

C

S

F

Q

I

Y

A

V

P

W

Q

G

T

M

T

L

S

K

S

T

C

Q

D

A

146

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1599
Peptide:	IVAGVNYFLD
Length:	10
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P01034
UniProt Name:	CYTC_HUMAN
Protein Name:	Cystatin-C
Position:	82-91

Literature

PMID:	26235923
Reference:	J Struct Biol. 2015 Sep;191(3):272-80.
source:	AmyLoad

Derived Information

Net Charge:	-1
Absolute Charge:	1
Hydrophobicity:	70.0
NuAPRpred:	2.05
Tango:	196.22

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	40.5
Area of the profile Above Threshold (AGGRESCAN):	4.38
Best Energy Score (PASTA 2.0):	-6.2
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

S

R

S

V

A

L

A

V

L

A

L

S

L

S

G

L

E

A

I

Q

R

T

P

K

I

Q

V

Y

S

R

H

P

A

E

N

G

K

S

N

F

L

N

C

Y

V

S

G

F

H

P

S

D

I

E

V

D

L

60

61

K

N

G

E

R

I

E

K

V

E

H

S

D

L

S

F

S

K

D

W

S

F

Y

L

Y

T

E

F

T

P

T

E

K

D

E

Y

A

C

R

V

N

H

V

T

L

S

Q

P

K

I

V

K

W

D

R

D

M

119

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1600
Peptide:	KDWSFYLLYY
Length:	10
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P61769
UniProt Name:	B2MG_HUMAN
Protein Name:	Beta-2-microglobulin
Position:	78-87

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	CPAD, AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	2
Hydrophobicity:	70.0
NuAPRpred:	2.21
Tango:	659.41

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	51.4
Area of the profile Above Threshold (AGGRESCAN):	6.8
Best Energy Score (PASTA 2.0):	-3.99
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

S

D

S

N

Q

G

N

Q

N

Y

Q

Y

S

Q

N

G

N

Q

G

N

R

Y

Q

G

Y

Q

A

Y

N

A

Q

A

Q

P

A

G

Y

Q

N

Y

Q

G

Y

S

G

Y

Q

G

Y

60

61

Q

Y

N

P

D

A

G

Y

Q

Y

N

P

Q

G

Y

Q

Y

N

P

Q

G

Y

Q

F

N

P

Q

G

R

G

N

Y

K

N

F

N

Y

N

L

Q

G

Y

Q

A

G

F

Q

P

Q

120

121

S

Q

G

M

S

L

N

D

F

Q

K

Q

K

Q

A

P

K

P

K

T

L

K

L

V

S

G

I

K

L

A

N

A

T

K

V

G

T

K

P

A

E

S

D

K

E

K

S

A

E

T

K

180

181

E

P

T

K

E

P

T

K

V

E

P

V

K

E

K

P

V

Q

T

E

K

T

E

K

S

E

L

P

K

V

E

D

L

K

I

S

E

S

T

H

N

T

N

A

N

V

T

S

A

D

A

L

I

K

240

241

E

Q

E

V

D

E

V

N

D

M

F

G

K

D

H

V

S

L

I

F

M

G

H

V

D

A

G

K

S

T

M

G

N

L

Y

L

T

G

S

V

D

K

R

T

I

E

K

Y

E

R

E

A

K

300

301

D

A

G

R

Q

G

W

Y

L

S

W

V

M

D

T

N

K

E

R

N

D

G

K

T

I

E

V

G

K

A

Y

F

E

T

E

K

R

Y

T

I

L

D

A

P

G

H

K

M

Y

V

S

E

M

I

G

A

S

360

361

Q

A

D

V

G

V

L

V

I

S

A

R

K

G

E

Y

E

T

G

F

E

R

G

Q

T

R

E

H

A

L

A

K

T

Q

G

V

N

K

M

V

N

K

M

D

P

T

V

N

W

S

K

E

R

Y

420

421

D

Q

C

V

S

N

V

S

N

F

L

R

A

I

G

Y

N

I

K

T

D

V

F

M

P

V

S

G

Y

S

G

A

N

L

K

D

H

V

D

P

K

E

C

P

W

Y

T

G

P

T

L

E

Y

L

D

T

M

N

480

481

H

V

D

R

H

I

N

A

P

F

M

L

P

I

A

K

M

K

D

L

G

T

I

V

E

G

K

I

E

S

G

H

I

K

G

Q

S

T

L

M

P

N

K

T

A

V

E

I

Q

N

I

Y

N

E

T

E

N

540

541

E

V

D

M

A

M

C

G

E

Q

V

K

L

R

I

K

G

V

E

D

I

S

P

G

F

V

L

T

S

P

K

N

P

I

K

S

V

T

K

F

V

A

Q

I

A

I

V

E

L

K

S

I

A

G

F

S

600

601

C

V

M

H

V

H

T

A

I

E

V

H

I

V

K

L

H

K

L

E

K

G

T

N

R

K

S

K

P

A

F

A

K

G

M

K

V

I

A

V

L

E

T

E

A

P

V

C

V

E

T

Y

Q

D

Y

660

661

P

Q

L

G

R

F

T

L

R

D

Q

G

T

I

A

I

G

K

I

V

K

I

A

E

685

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1601
Peptide:	KEPTKVEEPV
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P05453
UniProt Name:	ERF3_YEAST
Protein Name:	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)
Position:	184-193

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	AmyLoad

Derived Information

Net Charge:	-1
Absolute Charge:	5
Hydrophobicity:	40.0
NuAPRpred:	-3.0
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-50.5
Area of the profile Above Threshold (AGGRESCAN):	0.03
Best Energy Score (PASTA 2.0):	-1.52
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

S

D

S

N

Q

G

N

Q

N

Y

Q

Y

S

Q

N

G

N

Q

G

N

R

Y

Q

G

Y

Q

A

Y

N

A

Q

A

Q

P

A

G

Y

Q

N

Y

Q

G

Y

S

G

Y

Q

G

Y

60

61

Q

Y

N

P

D

A

G

Y

Q

Y

N

P

Q

G

Y

Q

Y

N

P

Q

G

Y

Q

F

N

P

Q

G

R

G

N

Y

K

N

F

N

Y

N

L

Q

G

Y

Q

A

G

F

Q

P

Q

120

121

S

Q

G

M

S

L

N

D

F

Q

K

Q

K

Q

A

P

K

P

K

T

L

K

L

V

S

G

I

K

L

A

N

A

T

K

V

G

T

K

P

A

E

S

D

K

E

K

S

A

E

T

K

180

181

E

P

T

K

E

P

T

K

V

E

P

V

K

E

K

P

V

Q

T

E

K

T

E

K

S

E

L

P

K

V

E

D

L

K

I

S

E

S

T

H

N

T

N

A

N

V

T

S

A

D

A

L

I

K

240

241

E

Q

E

V

D

E

V

N

D

M

F

G

K

D

H

V

S

L

I

F

M

G

H

V

D

A

G

K

S

T

M

G

N

L

Y

L

T

G

S

V

D

K

R

T

I

E

K

Y

E

R

E

A

K

300

301

D

A

G

R

Q

G

W

Y

L

S

W

V

M

D

T

N

K

E

R

N

D

G

K

T

I

E

V

G

K

A

Y

F

E

T

E

K

R

Y

T

I

L

D

A

P

G

H

K

M

Y

V

S

E

M

I

G

A

S

360

361

Q

A

D

V

G

V

L

V

I

S

A

R

K

G

E

Y

E

T

G

F

E

R

G

Q

T

R

E

H

A

L

A

K

T

Q

G

V

N

K

M

V

N

K

M

D

P

T

V

N

W

S

K

E

R

Y

420

421

D

Q

C

V

S

N

V

S

N

F

L

R

A

I

G

Y

N

I

K

T

D

V

F

M

P

V

S

G

Y

S

G

A

N

L

K

D

H

V

D

P

K

E

C

P

W

Y

T

G

P

T

L

E

Y

L

D

T

M

N

480

481

H

V

D

R

H

I

N

A

P

F

M

L

P

I

A

K

M

K

D

L

G

T

I

V

E

G

K

I

E

S

G

H

I

K

G

Q

S

T

L

M

P

N

K

T

A

V

E

I

Q

N

I

Y

N

E

T

E

N

540

541

E

V

D

M

A

M

C

G

E

Q

V

K

L

R

I

K

G

V

E

D

I

S

P

G

F

V

L

T

S

P

K

N

P

I

K

S

V

T

K

F

V

A

Q

I

A

I

V

E

L

K

S

I

A

G

F

S

600

601

C

V

M

H

V

H

T

A

I

E

V

H

I

V

K

L

H

K

L

E

K

G

T

N

R

K

S

K

P

A

F

A

K

G

M

K

V

I

A

V

L

E

T

E

A

P

V

C

V

E

T

Y

Q

D

Y

660

661

P

Q

L

G

R

F

T

L

R

D

Q

G

T

I

A

I

G

K

I

V

K

I

A

E

685

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1602
Peptide:	KLVSSSGIKL
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P05453
UniProt Name:	ERF3_YEAST
Protein Name:	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)
Position:	145-154

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	AmyLoad

Derived Information

Net Charge:	2
Absolute Charge:	2
Hydrophobicity:	40.0
NuAPRpred:	-0.79
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	13.8
Area of the profile Above Threshold (AGGRESCAN):	1.63
Best Energy Score (PASTA 2.0):	-1.43
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

L

E

V

L

G

S

G

D

G

S

L

V

F

V

P

S

E

F

S

V

P

S

G

E

K

I

V

F

K

N

A

G

F

P

H

N

V

F

D

E

D

E

I

P

A

G

V

D

A

V

K

I

S

M

P

E

60

61

E

L

N

A

P

G

E

T

Y

V

T

L

D

T

K

G

T

Y

S

F

Y

C

S

P

H

Q

G

A

G

M

V

G

K

V

T

V

N

99

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1603
Peptide:	KNNAGFPHNV
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P00287
UniProt Name:	PLAS_PHAVU
Protein Name:	Plastocyanin
Position:	30-39

Literature

PMID:	1507228
Reference:	J Mol Biol. 1992 Aug 5;226(3):819-35.
source:	AmyLoad

Derived Information

Net Charge:	1
Absolute Charge:	1
Hydrophobicity:	40.0
NuAPRpred:	-2.81
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-43.3
Area of the profile Above Threshold (AGGRESCAN):	0.16
Best Energy Score (PASTA 2.0):	0.4
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

S

D

S

N

Q

G

N

Q

N

Y

Q

Y

S

Q

N

G

N

Q

G

N

R

Y

Q

G

Y

Q

A

Y

N

A

Q

A

Q

P

A

G

Y

Q

N

Y

Q

G

Y

S

G

Y

Q

G

Y

60

61

Q

Y

N

P

D

A

G

Y

Q

Y

N

P

Q

G

Y

Q

Y

N

P

Q

G

Y

Q

F

N

P

Q

G

R

G

N

Y

K

N

F

N

Y

N

L

Q

G

Y

Q

A

G

F

Q

P

Q

120

121

S

Q

G

M

S

L

N

D

F

Q

K

Q

K

Q

A

P

K

P

K

T

L

K

L

V

S

G

I

K

L

A

N

A

T

K

V

G

T

K

P

A

E

S

D

K

E

K

S

A

E

T

K

180

181

E

P

T

K

E

P

T

K

V

E

P

V

K

E

K

P

V

Q

T

E

K

T

E

K

S

E

L

P

K

V

E

D

L

K

I

S

E

S

T

H

N

T

N

A

N

V

T

S

A

D

A

L

I

K

240

241

E

Q

E

V

D

E

V

N

D

M

F

G

K

D

H

V

S

L

I

F

M

G

H

V

D

A

G

K

S

T

M

G

N

L

Y

L

T

G

S

V

D

K

R

T

I

E

K

Y

E

R

E

A

K

300

301

D

A

G

R

Q

G

W

Y

L

S

W

V

M

D

T

N

K

E

R

N

D

G

K

T

I

E

V

G

K

A

Y

F

E

T

E

K

R

Y

T

I

L

D

A

P

G

H

K

M

Y

V

S

E

M

I

G

A

S

360

361

Q

A

D

V

G

V

L

V

I

S

A

R

K

G

E

Y

E

T

G

F

E

R

G

Q

T

R

E

H

A

L

A

K

T

Q

G

V

N

K

M

V

N

K

M

D

P

T

V

N

W

S

K

E

R

Y

420

421

D

Q

C

V

S

N

V

S

N

F

L

R

A

I

G

Y

N

I

K

T

D

V

F

M

P

V

S

G

Y

S

G

A

N

L

K

D

H

V

D

P

K

E

C

P

W

Y

T

G

P

T

L

E

Y

L

D

T

M

N

480

481

H

V

D

R

H

I

N

A

P

F

M

L

P

I

A

K

M

K

D

L

G

T

I

V

E

G

K

I

E

S

G

H

I

K

G

Q

S

T

L

M

P

N

K

T

A

V

E

I

Q

N

I

Y

N

E

T

E

N

540

541

E

V

D

M

A

M

C

G

E

Q

V

K

L

R

I

K

G

V

E

D

I

S

P

G

F

V

L

T

S

P

K

N

P

I

K

S

V

T

K

F

V

A

Q

I

A

I

V

E

L

K

S

I

A

G

F

S

600

601

C

V

M

H

V

H

T

A

I

E

V

H

I

V

K

L

H

K

L

E

K

G

T

N

R

K

S

K

P

A

F

A

K

G

M

K

V

I

A

V

L

E

T

E

A

P

V

C

V

E

T

Y

Q

D

Y

660

661

P

Q

L

G

R

F

T

L

R

D

Q

G

T

I

A

I

G

K

I

V

K

I

A

E

685

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1604
Peptide:	KPKKTLKLVS
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P05453
UniProt Name:	ERF3_YEAST
Protein Name:	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)
Position:	139-148

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	AmyLoad

Derived Information

Net Charge:	4
Absolute Charge:	4
Hydrophobicity:	40.0
NuAPRpred:	-0.96
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-13.7
Area of the profile Above Threshold (AGGRESCAN):	1.79
Best Energy Score (PASTA 2.0):	-2.26
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

A

N

L

G

C

W

M

L

V

L

F

V

A

T

W

S

D

L

G

L

C

K

R

P

K

P

G

W

N

T

G

S

R

Y

P

G

Q

G

S

P

G

N

R

Y

P

Q

G

W

G

Q

P

60

61

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

G

T

H

S

Q

W

N

K

P

S

K

P

K

T

N

M

K

H

M

A

G

A

G

A

120

121

V

G

L

G

Y

M

L

G

S

A

M

S

R

P

I

H

F

G

S

D

Y

E

D

R

Y

R

E

N

M

H

R

Y

P

N

Q

V

Y

R

P

M

D

E

Y

S

N

Q

N

F

V

H

D

C

V

180

181

N

I

T

I

K

Q

H

T

V

T

K

G

E

N

F

T

E

T

D

V

K

M

E

R

V

E

Q

M

C

I

T

Q

Y

E

R

E

S

Q

A

Y

Q

R

G

S

M

V

L

F

S

P

V

240

241

I

L

I

S

F

L

I

F

L

I

V

G

253

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1605
Peptide:	KPSKPKTNMK
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P04156
UniProt Name:	PRIO_HUMAN
Protein Name:	Major prion protein (PrP)
Position:	101-110

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	4
Absolute Charge:	4
Hydrophobicity:	30.0
NuAPRpred:	-3.14
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-59.1
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	1.1
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

S

D

S

N

Q

G

N

Q

N

Y

Q

Y

S

Q

N

G

N

Q

G

N

R

Y

Q

G

Y

Q

A

Y

N

A

Q

A

Q

P

A

G

Y

Q

N

Y

Q

G

Y

S

G

Y

Q

G

Y

60

61

Q

Y

N

P

D

A

G

Y

Q

Y

N

P

Q

G

Y

Q

Y

N

P

Q

G

Y

Q

F

N

P

Q

G

R

G

N

Y

K

N

F

N

Y

N

L

Q

G

Y

Q

A

G

F

Q

P

Q

120

121

S

Q

G

M

S

L

N

D

F

Q

K

Q

K

Q

A

P

K

P

K

T

L

K

L

V

S

G

I

K

L

A

N

A

T

K

V

G

T

K

P

A

E

S

D

K

E

K

S

A

E

T

K

180

181

E

P

T

K

E

P

T

K

V

E

P

V

K

E

K

P

V

Q

T

E

K

T

E

K

S

E

L

P

K

V

E

D

L

K

I

S

E

S

T

H

N

T

N

A

N

V

T

S

A

D

A

L

I

K

240

241

E

Q

E

V

D

E

V

N

D

M

F

G

K

D

H

V

S

L

I

F

M

G

H

V

D

A

G

K

S

T

M

G

N

L

Y

L

T

G

S

V

D

K

R

T

I

E

K

Y

E

R

E

A

K

300

301

D

A

G

R

Q

G

W

Y

L

S

W

V

M

D

T

N

K

E

R

N

D

G

K

T

I

E

V

G

K

A

Y

F

E

T

E

K

R

Y

T

I

L

D

A

P

G

H

K

M

Y

V

S

E

M

I

G

A

S

360

361

Q

A

D

V

G

V

L

V

I

S

A

R

K

G

E

Y

E

T

G

F

E

R

G

Q

T

R

E

H

A

L

A

K

T

Q

G

V

N

K

M

V

N

K

M

D

P

T

V

N

W

S

K

E

R

Y

420

421

D

Q

C

V

S

N

V

S

N

F

L

R

A

I

G

Y

N

I

K

T

D

V

F

M

P

V

S

G

Y

S

G

A

N

L

K

D

H

V

D

P

K

E

C

P

W

Y

T

G

P

T

L

E

Y

L

D

T

M

N

480

481

H

V

D

R

H

I

N

A

P

F

M

L

P

I

A

K

M

K

D

L

G

T

I

V

E

G

K

I

E

S

G

H

I

K

G

Q

S

T

L

M

P

N

K

T

A

V

E

I

Q

N

I

Y

N

E

T

E

N

540

541

E

V

D

M

A

M

C

G

E

Q

V

K

L

R

I

K

G

V

E

D

I

S

P

G

F

V

L

T

S

P

K

N

P

I

K

S

V

T

K

F

V

A

Q

I

A

I

V

E

L

K

S

I

A

G

F

S

600

601

C

V

M

H

V

H

T

A

I

E

V

H

I

V

K

L

H

K

L

E

K

G

T

N

R

K

S

K

P

A

F

A

K

G

M

K

V

I

A

V

L

E

T

E

A

P

V

C

V

E

T

Y

Q

D

Y

660

661

P

Q

L

G

R

F

T

L

R

D

Q

G

T

I

A

I

G

K

I

V

K

I

A

E

685

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1606
Peptide:	KSAETKEPTK
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P05453
UniProt Name:	ERF3_YEAST
Protein Name:	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)
Position:	175-184

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	AmyLoad

Derived Information

Net Charge:	1
Absolute Charge:	5
Hydrophobicity:	20.0
NuAPRpred:	-3.04
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-74.1
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	-0.05
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

S

D

S

N

Q

G

N

Q

N

Y

Q

Y

S

Q

N

G

N

Q

G

N

R

Y

Q

G

Y

Q

A

Y

N

A

Q

A

Q

P

A

G

Y

Q

N

Y

Q

G

Y

S

G

Y

Q

G

Y

60

61

Q

Y

N

P

D

A

G

Y

Q

Y

N

P

Q

G

Y

Q

Y

N

P

Q

G

Y

Q

F

N

P

Q

G

R

G

N

Y

K

N

F

N

Y

N

L

Q

G

Y

Q

A

G

F

Q

P

Q

120

121

S

Q

G

M

S

L

N

D

F

Q

K

Q

K

Q

A

P

K

P

K

T

L

K

L

V

S

G

I

K

L

A

N

A

T

K

V

G

T

K

P

A

E

S

D

K

E

K

S

A

E

T

K

180

181

E

P

T

K

E

P

T

K

V

E

P

V

K

E

K

P

V

Q

T

E

K

T

E

K

S

E

L

P

K

V

E

D

L

K

I

S

E

S

T

H

N

T

N

A

N

V

T

S

A

D

A

L

I

K

240

241

E

Q

E

V

D

E

V

N

D

M

F

G

K

D

H

V

S

L

I

F

M

G

H

V

D

A

G

K

S

T

M

G

N

L

Y

L

T

G

S

V

D

K

R

T

I

E

K

Y

E

R

E

A

K

300

301

D

A

G

R

Q

G

W

Y

L

S

W

V

M

D

T

N

K

E

R

N

D

G

K

T

I

E

V

G

K

A

Y

F

E

T

E

K

R

Y

T

I

L

D

A

P

G

H

K

M

Y

V

S

E

M

I

G

A

S

360

361

Q

A

D

V

G

V

L

V

I

S

A

R

K

G

E

Y

E

T

G

F

E

R

G

Q

T

R

E

H

A

L

A

K

T

Q

G

V

N

K

M

V

N

K

M

D

P

T

V

N

W

S

K

E

R

Y

420

421

D

Q

C

V

S

N

V

S

N

F

L

R

A

I

G

Y

N

I

K

T

D

V

F

M

P

V

S

G

Y

S

G

A

N

L

K

D

H

V

D

P

K

E

C

P

W

Y

T

G

P

T

L

E

Y

L

D

T

M

N

480

481

H

V

D

R

H

I

N

A

P

F

M

L

P

I

A

K

M

K

D

L

G

T

I

V

E

G

K

I

E

S

G

H

I

K

G

Q

S

T

L

M

P

N

K

T

A

V

E

I

Q

N

I

Y

N

E

T

E

N

540

541

E

V

D

M

A

M

C

G

E

Q

V

K

L

R

I

K

G

V

E

D

I

S

P

G

F

V

L

T

S

P

K

N

P

I

K

S

V

T

K

F

V

A

Q

I

A

I

V

E

L

K

S

I

A

G

F

S

600

601

C

V

M

H

V

H

T

A

I

E

V

H

I

V

K

L

H

K

L

E

K

G

T

N

R

K

S

K

P

A

F

A

K

G

M

K

V

I

A

V

L

E

T

E

A

P

V

C

V

E

T

Y

Q

D

Y

660

661

P

Q

L

G

R

F

T

L

R

D

Q

G

T

I

A

I

G

K

I

V

K

I

A

E

685

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1607
Peptide:	KTEEKSELPK
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P05453
UniProt Name:	ERF3_YEAST
Protein Name:	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)
Position:	205-214

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	6
Hydrophobicity:	20.0
NuAPRpred:	-2.62
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-72.4
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	-0.29
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

S

D

S

N

Q

G

N

Q

N

Y

Q

Y

S

Q

N

G

N

Q

G

N

R

Y

Q

G

Y

Q

A

Y

N

A

Q

A

Q

P

A

G

Y

Q

N

Y

Q

G

Y

S

G

Y

Q

G

Y

60

61

Q

Y

N

P

D

A

G

Y

Q

Y

N

P

Q

G

Y

Q

Y

N

P

Q

G

Y

Q

F

N

P

Q

G

R

G

N

Y

K

N

F

N

Y

N

L

Q

G

Y

Q

A

G

F

Q

P

Q

120

121

S

Q

G

M

S

L

N

D

F

Q

K

Q

K

Q

A

P

K

P

K

T

L

K

L

V

S

G

I

K

L

A

N

A

T

K

V

G

T

K

P

A

E

S

D

K

E

K

S

A

E

T

K

180

181

E

P

T

K

E

P

T

K

V

E

P

V

K

E

K

P

V

Q

T

E

K

T

E

K

S

E

L

P

K

V

E

D

L

K

I

S

E

S

T

H

N

T

N

A

N

V

T

S

A

D

A

L

I

K

240

241

E

Q

E

V

D

E

V

N

D

M

F

G

K

D

H

V

S

L

I

F

M

G

H

V

D

A

G

K

S

T

M

G

N

L

Y

L

T

G

S

V

D

K

R

T

I

E

K

Y

E

R

E

A

K

300

301

D

A

G

R

Q

G

W

Y

L

S

W

V

M

D

T

N

K

E

R

N

D

G

K

T

I

E

V

G

K

A

Y

F

E

T

E

K

R

Y

T

I

L

D

A

P

G

H

K

M

Y

V

S

E

M

I

G

A

S

360

361

Q

A

D

V

G

V

L

V

I

S

A

R

K

G

E

Y

E

T

G

F

E

R

G

Q

T

R

E

H

A

L

A

K

T

Q

G

V

N

K

M

V

N

K

M

D

P

T

V

N

W

S

K

E

R

Y

420

421

D

Q

C

V

S

N

V

S

N

F

L

R

A

I

G

Y

N

I

K

T

D

V

F

M

P

V

S

G

Y

S

G

A

N

L

K

D

H

V

D

P

K

E

C

P

W

Y

T

G

P

T

L

E

Y

L

D

T

M

N

480

481

H

V

D

R

H

I

N

A

P

F

M

L

P

I

A

K

M

K

D

L

G

T

I

V

E

G

K

I

E

S

G

H

I

K

G

Q

S

T

L

M

P

N

K

T

A

V

E

I

Q

N

I

Y

N

E

T

E

N

540

541

E

V

D

M

A

M

C

G

E

Q

V

K

L

R

I

K

G

V

E

D

I

S

P

G

F

V

L

T

S

P

K

N

P

I

K

S

V

T

K

F

V

A

Q

I

A

I

V

E

L

K

S

I

A

G

F

S

600

601

C

V

M

H

V

H

T

A

I

E

V

H

I

V

K

L

H

K

L

E

K

G

T

N

R

K

S

K

P

A

F

A

K

G

M

K

V

I

A

V

L

E

T

E

A

P

V

C

V

E

T

Y

Q

D

Y

660

661

P

Q

L

G

R

F

T

L

R

D

Q

G

T

I

A

I

G

K

I

V

K

I

A

E

685

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1608
Peptide:	KTLKLVSSSG
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P05453
UniProt Name:	ERF3_YEAST
Protein Name:	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)
Position:	142-151

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	AmyLoad

Derived Information

Net Charge:	2
Absolute Charge:	2
Hydrophobicity:	30.0
NuAPRpred:	-0.26
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	2.6
Area of the profile Above Threshold (AGGRESCAN):	2.29
Best Energy Score (PASTA 2.0):	-2.26
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

A

N

L

G

C

W

M

L

V

L

F

V

A

T

W

S

D

L

G

L

C

K

R

P

K

P

G

W

N

T

G

S

R

Y

P

G

Q

G

S

P

G

N

R

Y

P

Q

G

W

G

Q

P

60

61

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

G

T

H

S

Q

W

N

K

P

S

K

P

K

T

N

M

K

H

M

A

G

A

G

A

120

121

V

G

L

G

Y

M

L

G

S

A

M

S

R

P

I

H

F

G

S

D

Y

E

D

R

Y

R

E

N

M

H

R

Y

P

N

Q

V

Y

R

P

M

D

E

Y

S

N

Q

N

F

V

H

D

C

V

180

181

N

I

T

I

K

Q

H

T

V

T

K

G

E

N

F

T

E

T

D

V

K

M

E

R

V

E

Q

M

C

I

T

Q

Y

E

R

E

S

Q

A

Y

Q

R

G

S

M

V

L

F

S

P

V

240

241

I

L

I

S

F

L

I

F

L

I

V

G

253

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1609
Peptide:	KTNMKHMAGA
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P04156
UniProt Name:	PRIO_HUMAN
Protein Name:	Major prion protein (PrP)
Position:	106-115

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	2
Absolute Charge:	2
Hydrophobicity:	40.0
NuAPRpred:	-1.56
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-33.4
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	0.02
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

S

R

S

V

A

L

A

V

L

A

L

S

L

S

G

L

E

A

I

Q

R

T

P

K

I

Q

V

Y

S

R

H

P

A

E

N

G

K

S

N

F

L

N

C

Y

V

S

G

F

H

P

S

D

I

E

V

D

L

60

61

K

N

G

E

R

I

E

K

V

E

H

S

D

L

S

F

S

K

D

W

S

F

Y

L

Y

T

E

F

T

P

T

E

K

D

E

Y

A

C

R

V

N

H

V

T

L

S

Q

P

K

I

V

K

W

D

R

D

M

119

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1610
Peptide:	KVEHSDLSFS
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P61769
UniProt Name:	B2MG_HUMAN
Protein Name:	Beta-2-microglobulin
Position:	68-77

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	-1
Absolute Charge:	3
Hydrophobicity:	30.0
NuAPRpred:	-1.85
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-25.6
Area of the profile Above Threshold (AGGRESCAN):	0.95
Best Energy Score (PASTA 2.0):	-0.31
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

S

D

S

N

Q

G

N

Q

N

Y

Q

Y

S

Q

N

G

N

Q

G

N

R

Y

Q

G

Y

Q

A

Y

N

A

Q

A

Q

P

A

G

Y

Q

N

Y

Q

G

Y

S

G

Y

Q

G

Y

60

61

Q

Y

N

P

D

A

G

Y

Q

Y

N

P

Q

G

Y

Q

Y

N

P

Q

G

Y

Q

F

N

P

Q

G

R

G

N

Y

K

N

F

N

Y

N

L

Q

G

Y

Q

A

G

F

Q

P

Q

120

121

S

Q

G

M

S

L

N

D

F

Q

K

Q

K

Q

A

P

K

P

K

T

L

K

L

V

S

G

I

K

L

A

N

A

T

K

V

G

T

K

P

A

E

S

D

K

E

K

S

A

E

T

K

180

181

E

P

T

K

E

P

T

K

V

E

P

V

K

E

K

P

V

Q

T

E

K

T

E

K

S

E

L

P

K

V

E

D

L

K

I

S

E

S

T

H

N

T

N

A

N

V

T

S

A

D

A

L

I

K

240

241

E

Q

E

V

D

E

V

N

D

M

F

G

K

D

H

V

S

L

I

F

M

G

H

V

D

A

G

K

S

T

M

G

N

L

Y

L

T

G

S

V

D

K

R

T

I

E

K

Y

E

R

E

A

K

300

301

D

A

G

R

Q

G

W

Y

L

S

W

V

M

D

T

N

K

E

R

N

D

G

K

T

I

E

V

G

K

A

Y

F

E

T

E

K

R

Y

T

I

L

D

A

P

G

H

K

M

Y

V

S

E

M

I

G

A

S

360

361

Q

A

D

V

G

V

L

V

I

S

A

R

K

G

E

Y

E

T

G

F

E

R

G

Q

T

R

E

H

A

L

A

K

T

Q

G

V

N

K

M

V

N

K

M

D

P

T

V

N

W

S

K

E

R

Y

420

421

D

Q

C

V

S

N

V

S

N

F

L

R

A

I

G

Y

N

I

K

T

D

V

F

M

P

V

S

G

Y

S

G

A

N

L

K

D

H

V

D

P

K

E

C

P

W

Y

T

G

P

T

L

E

Y

L

D

T

M

N

480

481

H

V

D

R

H

I

N

A

P

F

M

L

P

I

A

K

M

K

D

L

G

T

I

V

E

G

K

I

E

S

G

H

I

K

G

Q

S

T

L

M

P

N

K

T

A

V

E

I

Q

N

I

Y

N

E

T

E

N

540

541

E

V

D

M

A

M

C

G

E

Q

V

K

L

R

I

K

G

V

E

D

I

S

P

G

F

V

L

T

S

P

K

N

P

I

K

S

V

T

K

F

V

A

Q

I

A

I

V

E

L

K

S

I

A

G

F

S

600

601

C

V

M

H

V

H

T

A

I

E

V

H

I

V

K

L

H

K

L

E

K

G

T

N

R

K

S

K

P

A

F

A

K

G

M

K

V

I

A

V

L

E

T

E

A

P

V

C

V

E

T

Y

Q

D

Y

660

661

P

Q

L

G

R

F

T

L

R

D

Q

G

T

I

A

I

G

K

I

V

K

I

A

E

685

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1611
Peptide:	KVGTKPAESD
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P05453
UniProt Name:	ERF3_YEAST
Protein Name:	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)
Position:	160-169

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	4
Hydrophobicity:	30.0
NuAPRpred:	-3.05
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-51.5
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	-0.11
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

K

C

L

A

L

G

L

A

L

A

C

A

Q

A

I

V

T

Q

T

M

K

G

L

D

I

Q

K

V

A

G

T

W

Y

S

L

A

M

A

S

D

I

S

L

D

A

Q

S

A

P

L

R

V

Y

60

61

V

E

L

K

P

T

P

E

G

D

L

E

I

L

Q

K

W

E

N

G

E

C

A

Q

K

I

A

E

K

T

K

I

P

A

V

F

K

I

D

A

L

N

E

N

K

V

L

V

L

D

T

D

Y

K

Y

120

121

L

F

C

M

E

N

S

A

E

P

E

Q

S

L

A

C

Q

C

L

V

R

T

P

E

V

D

E

A

L

E

K

F

D

K

A

L

K

A

L

P

M

H

I

R

L

S

F

N

P

T

Q

L

E

Q

C

H

V

180

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1612
Peptide:	KYLLFCMENS
Length:	10
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P02755
UniProt Name:	LACB_BUBBU
Protein Name:	Beta-lactoglobulin (Beta-LG)
Position:	119-128

Literature

PMID:	19133274
Reference:	J Mol Biol. 2009 Feb 27;386(3):878-90.
source:	CPAD

Derived Information

Net Charge:	0
Absolute Charge:	2
Hydrophobicity:	60.0
NuAPRpred:	3.97
Tango:	381.46

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	31.4
Area of the profile Above Threshold (AGGRESCAN):	5.0
Best Energy Score (PASTA 2.0):	-3.09
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

S

D

S

N

Q

G

N

Q

N

Y

Q

Y

S

Q

N

G

N

Q

G

N

R

Y

Q

G

Y

Q

A

Y

N

A

Q

A

Q

P

A

G

Y

Q

N

Y

Q

G

Y

S

G

Y

Q

G

Y

60

61

Q

Y

N

P

D

A

G

Y

Q

Y

N

P

Q

G

Y

Q

Y

N

P

Q

G

Y

Q

F

N

P

Q

G

R

G

N

Y

K

N

F

N

Y

N

L

Q

G

Y

Q

A

G

F

Q

P

Q

120

121

S

Q

G

M

S

L

N

D

F

Q

K

Q

K

Q

A

P

K

P

K

T

L

K

L

V

S

G

I

K

L

A

N

A

T

K

V

G

T

K

P

A

E

S

D

K

E

K

S

A

E

T

K

180

181

E

P

T

K

E

P

T

K

V

E

P

V

K

E

K

P

V

Q

T

E

K

T

E

K

S

E

L

P

K

V

E

D

L

K

I

S

E

S

T

H

N

T

N

A

N

V

T

S

A

D

A

L

I

K

240

241

E

Q

E

V

D

E

V

N

D

M

F

G

K

D

H

V

S

L

I

F

M

G

H

V

D

A

G

K

S

T

M

G

N

L

Y

L

T

G

S

V

D

K

R

T

I

E

K

Y

E

R

E

A

K

300

301

D

A

G

R

Q

G

W

Y

L

S

W

V

M

D

T

N

K

E

R

N

D

G

K

T

I

E

V

G

K

A

Y

F

E

T

E

K

R

Y

T

I

L

D

A

P

G

H

K

M

Y

V

S

E

M

I

G

A

S

360

361

Q

A

D

V

G

V

L

V

I

S

A

R

K

G

E

Y

E

T

G

F

E

R

G

Q

T

R

E

H

A

L

A

K

T

Q

G

V

N

K

M

V

N

K

M

D

P

T

V

N

W

S

K

E

R

Y

420

421

D

Q

C

V

S

N

V

S

N

F

L

R

A

I

G

Y

N

I

K

T

D

V

F

M

P

V

S

G

Y

S

G

A

N

L

K

D

H

V

D

P

K

E

C

P

W

Y

T

G

P

T

L

E

Y

L

D

T

M

N

480

481

H

V

D

R

H

I

N

A

P

F

M

L

P

I

A

K

M

K

D

L

G

T

I

V

E

G

K

I

E

S

G

H

I

K

G

Q

S

T

L

M

P

N

K

T

A

V

E

I

Q

N

I

Y

N

E

T

E

N

540

541

E

V

D

M

A

M

C

G

E

Q

V

K

L

R

I

K

G

V

E

D

I

S

P

G

F

V

L

T

S

P

K

N

P

I

K

S

V

T

K

F

V

A

Q

I

A

I

V

E

L

K

S

I

A

G

F

S

600

601

C

V

M

H

V

H

T

A

I

E

V

H

I

V

K

L

H

K

L

E

K

G

T

N

R

K

S

K

P

A

F

A

K

G

M

K

V

I

A

V

L

E

T

E

A

P

V

C

V

E

T

Y

Q

D

Y

660

661

P

Q

L

G

R

F

T

L

R

D

Q

G

T

I

A

I

G

K

I

V

K

I

A

E

685

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1613
Peptide:	LANATKKVGT
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P05453
UniProt Name:	ERF3_YEAST
Protein Name:	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)
Position:	154-163

Literature

PMID:	20154676
Reference:	Nat Methods. 2010 Mar;7(3):237-42.
source:	AmyLoad

Derived Information

Net Charge:	2
Absolute Charge:	2
Hydrophobicity:	40.0
NuAPRpred:	-1.66
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-27.7
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	-0.36
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

K

A

L

I

V

L

G

L

V

L

S

V

T

V

Q

G

K

V

F

E

R

C

E

L

A

R

T

L

K

R

L

G

M

D

G

Y

R

G

I

S

L

A

N

W

M

C

L

A

K

W

E

S

G

Y

N

T

R

A

60

61

T

N

Y

N

A

G

D

R

S

T

D

Y

G

I

F

Q

I

N

S

R

Y

W

C

N

D

G

K

T

P

G

A

V

N

A

C

H

L

S

C

S

A

L

Q

D

N

I

A

D

A

V

A

C

A

K

R

V

R

D

120

121

P

Q

G

I

R

A

W

V

A

W

R

N

R

C

Q

N

R

D

V

R

Q

Y

V

Q

G

C

G

V

148

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1614
Peptide:	LANWMCLAKW
Length:	10
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P61626
UniProt Name:	LYSC_HUMAN
Protein Name:	Lysozyme C
Position:	43-52

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	CPAD, AmyLoad

Derived Information

Net Charge:	1
Absolute Charge:	1
Hydrophobicity:	80.0
NuAPRpred:	3.81
Tango:	19.69

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	26.7
Area of the profile Above Threshold (AGGRESCAN):	3.05
Best Energy Score (PASTA 2.0):	-2.14
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

K

A

L

I

V

L

G

L

V

L

S

V

T

V

Q

G

K

V

F

E

R

C

E

L

A

R

T

L

K

R

L

G

M

D

G

Y

R

G

I

S

L

A

N

W

M

C

L

A

K

W

E

S

G

Y

N

T

R

A

60

61

T

N

Y

N

A

G

D

R

S

T

D

Y

G

I

F

Q

I

N

S

R

Y

W

C

N

D

G

K

T

P

G

A

V

N

A

C

H

L

S

C

S

A

L

Q

D

N

I

A

D

A

V

A

C

A

K

R

V

R

D

120

121

P

Q

G

I

R

A

W

V

A

W

R

N

R

C

Q

N

R

D

V

R

Q

Y

V

Q

G

C

G

V

148

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1615
Peptide:	LGMDGYRGIS
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P61626
UniProt Name:	LYSC_HUMAN
Protein Name:	Lysozyme C
Position:	33-42

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	2
Hydrophobicity:	40.0
NuAPRpred:	-2.69
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-20.9
Area of the profile Above Threshold (AGGRESCAN):	0.36
Best Energy Score (PASTA 2.0):	0.18
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

S

R

S

V

A

L

A

V

L

A

L

S

L

S

G

L

E

A

I

Q

R

T

P

K

I

Q

V

Y

S

R

H

P

A

E

N

G

K

S

N

F

L

N

C

Y

V

S

G

F

H

P

S

D

I

E

V

D

L

60

61

K

N

G

E

R

I

E

K

V

E

H

S

D

L

S

F

S

K

D

W

S

F

Y

L

Y

T

E

F

T

P

T

E

K

D

E

Y

A

C

R

V

N

H

V

T

L

S

Q

P

K

I

V

K

W

D

R

D

M

119

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1616
Peptide:	LNCYVSGFHP
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P61769
UniProt Name:	B2MG_HUMAN
Protein Name:	Beta-2-microglobulin
Position:	43-52

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	60.0
NuAPRpred:	1.9
Tango:	1.47

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	20.8
Area of the profile Above Threshold (AGGRESCAN):	2.84
Best Energy Score (PASTA 2.0):	-3.24
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

K

A

L

I

V

L

G

L

V

L

S

V

T

V

Q

G

K

V

F

E

R

C

E

L

A

R

T

L

K

R

L

G

M

D

G

Y

R

G

I

S

L

A

N

W

M

C

L

A

K

W

E

S

G

Y

N

T

R

A

60

61

T

N

Y

N

A

G

D

R

S

T

D

Y

G

I

F

Q

I

N

S

R

Y

W

C

N

D

G

K

T

P

G

A

V

N

A

C

H

L

S

C

S

A

L

Q

D

N

I

A

D

A

V

A

C

A

K

R

V

R

D

120

121

P

Q

G

I

R

A

W

V

A

W

R

N

R

C

Q

N

R

D

V

R

Q

Y

V

Q

G

C

G

V

148

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1617
Peptide:	LQDNIADAVA
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P61626
UniProt Name:	LYSC_HUMAN
Protein Name:	Lysozyme C
Position:	103-112

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	-2
Absolute Charge:	2
Hydrophobicity:	60.0
NuAPRpred:	-0.88
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-38.4
Area of the profile Above Threshold (AGGRESCAN):	0.32
Best Energy Score (PASTA 2.0):	-1.49
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

A

N

L

G

C

W

M

L

V

L

F

V

A

T

W

S

D

L

G

L

C

K

R

P

K

P

G

W

N

T

G

S

R

Y

P

G

Q

G

S

P

G

N

R

Y

P

Q

G

W

G

Q

P

60

61

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

G

T

H

S

Q

W

N

K

P

S

K

P

K

T

N

M

K

H

M

A

G

A

G

A

120

121

V

G

L

G

Y

M

L

G

S

A

M

S

R

P

I

H

F

G

S

D

Y

E

D

R

Y

R

E

N

M

H

R

Y

P

N

Q

V

Y

R

P

M

D

E

Y

S

N

Q

N

F

V

H

D

C

V

180

181

N

I

T

I

K

Q

H

T

V

T

K

G

E

N

F

T

E

T

D

V

K

M

E

R

V

E

Q

M

C

I

T

Q

Y

E

R

E

S

Q

A

Y

Q

R

G

S

M

V

L

F

S

P

V

240

241

I

L

I

S

F

L

I

F

L

I

V

G

253

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1618
Peptide:	MDEYSNQNNF
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P04156
UniProt Name:	PRIO_HUMAN
Protein Name:	Major prion protein (PrP)
Position:	166-175

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	-2
Absolute Charge:	2
Hydrophobicity:	30.0
NuAPRpred:	-1.9
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-63.9
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	0.49
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

A

N

L

G

C

W

M

L

V

L

F

V

A

T

W

S

D

L

G

L

C

K

R

P

K

P

G

W

N

T

G

S

R

Y

P

G

Q

G

S

P

G

N

R

Y

P

Q

G

W

G

Q

P

60

61

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

G

T

H

S

Q

W

N

K

P

S

K

P

K

T

N

M

K

H

M

A

G

A

G

A

120

121

V

G

L

G

Y

M

L

G

S

A

M

S

R

P

I

H

F

G

S

D

Y

E

D

R

Y

R

E

N

M

H

R

Y

P

N

Q

V

Y

R

P

M

D

E

Y

S

N

Q

N

F

V

H

D

C

V

180

181

N

I

T

I

K

Q

H

T

V

T

K

G

E

N

F

T

E

T

D

V

K

M

E

R

V

E

Q

M

C

I

T

Q

Y

E

R

E

S

Q

A

Y

Q

R

G

S

M

V

L

F

S

P

V

240

241

I

L

I

S

F

L

I

F

L

I

V

G

253

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1619
Peptide:	MERVVEQMCI
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P04156
UniProt Name:	PRIO_HUMAN
Protein Name:	Major prion protein (PrP)
Position:	206-215

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	-1
Absolute Charge:	3
Hydrophobicity:	60.0
NuAPRpred:	1.07
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	2.0
Area of the profile Above Threshold (AGGRESCAN):	1.34
Best Energy Score (PASTA 2.0):	-3.04
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

K

A

L

I

V

L

G

L

V

L

S

V

T

V

Q

G

K

V

F

E

R

C

E

L

A

R

T

L

K

R

L

G

M

D

G

Y

R

G

I

S

L

A

N

W

M

C

L

A

K

W

E

S

G

Y

N

T

R

A

60

61

T

N

Y

N

A

G

D

R

S

T

D

Y

G

I

F

Q

I

N

S

R

Y

W

C

N

D

G

K

T

P

G

A

V

N

A

C

H

L

S

C

S

A

L

Q

D

N

I

A

D

A

V

A

C

A

K

R

V

R

D

120

121

P

Q

G

I

R

A

W

V

A

W

R

N

R

C

Q

N

R

D

V

R

Q

Y

V

Q

G

C

G

V

148

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1620
Peptide:	NACHLSCSAL
Length:	10
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P61626
UniProt Name:	LYSC_HUMAN
Protein Name:	Lysozyme C
Position:	93-102

Literature

PMID:	15361882
Reference:	Nat Biotechnol. 2004 Oct;22(10):1302-6.
source:	AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	60.0
NuAPRpred:	2.96
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-2.1
Area of the profile Above Threshold (AGGRESCAN):	1.36
Best Energy Score (PASTA 2.0):	-3.38
Aggregate Orientation (PASTA 2.0):	Antiparallel

Database of known aggregating/non-aggregating peptides

Displaying 1591 to 1620 records out of 2031 records fetched.