CPAD 2.0

Entry	Peptide	Length	Class	Protein Name	UniProt ID	Mutant	Reference	PMID	Source Database
P-1891	QTAPVPMPDLKNVKSKIGSTE	21	Non-amyloid	Microtubule-associated protein tau (PHF-tau)	P10636		Proc Natl Acad Sci U S A. 2000 May 9;97(10):5129-34.	10805776	AmyLoad
P-1892	SGYEVHHQKLVFFAEDVGSNK	21	Amyloid	Amyloid-beta precursor protein (APP)	P05067	No	Biochemistry. 1995 Jan 24;34(3):724-30; J Biol Chem. 2002 Nov 8;277(45):43243-6.	7827029 1	CPAD, AmyLoad
P-1893	STAAMSTYTGIFTDQVLSVLK	21	Amyloid	Apolipoprotein C-II (ApoC-II)	P02655	No	J Mol Biol. 2007 Mar 9;366(5):1639-51.	17217959	CPAD
P-1894	TNVKHVAGAAAAGAVVGGLGG	21	Amyloid	Major prion protein (PrP)	P04156	M108V, M111V	J Mol Biol. 2008 May 16;378(5):1142-54.	18423487	CPAD
P-1895	TRRTTFESVGRWLDELKIHSD	21	Non-amyloid	Ras-related protein RABA5e (AtRABA5e) (Ras-related protein Ara-1)	P19892	No	Protein Sci. 1995 Aug;4(8):1577-86.	8520484	AmyLoad
P-1896	VTIKANLIFANGFTQTAEFKG	21	Amyloid				Protein Sci. 1997 Jan;6(1):162-74.	9007989	CPAD, AmyLoad
P-1897	YEQLDEEHKKIFKGIFDCIRD	21	Amyloid	Myohemerythrin (MHr)	P02247	No	J Mol Biol. 1992 Aug 5;226(3):795-817.	1507227	CPAD, AmyLoad
P-1898	DAALHFNPRLDTSEVVFNSKEQ	22	Non-amyloid	Galectin-7	P47929	No	J Biol Chem. 2014 Oct 17;289(42):29195-207	25172508	CPAD
P-1899	DDNNQQNYQQYSQNGNQQQGKK	22	Amyloid	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)	P05453		Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5591-5.	11960014	CPAD
P-1900	ELEAQVINTFDGVADYLQTYHK	22	Amyloid	Ribonuclease (Barnase)	P00648	H45E, T46L	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.	16499867	CPAD
P-1901	ELSAQVINTFDGVADYLQTYHK	22	Amyloid	Ribonuclease (Barnase)	P00648	H45E, T46L, E47S	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.	16499867	CPAD
P-1902	ESLAQVINTFDGVADYLQTYHK	22	Amyloid	Ribonuclease (Barnase)	P00648	H45E, T46S, E47L	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.	16499867	CPAD
P-1903	GTVSFVTSPHQGAGMVGKVTVN	22	Amyloid			No	J Mol Biol. 1992 Aug 5;226(3):795-817.	1507227	CPAD, AmyLoad
P-1904	KDRVQSKIGSLDNITHVPGGGN	22	Non-amyloid	Microtubule-associated protein tau (PHF-tau)	P10636		Proc Natl Acad Sci U S A. 2000 May 9;97(10):5129-34.	10805776	AmyLoad
P-1905	KLSAQVINTFDGVADYLQTYHK	22	Amyloid	Ribonuclease (Barnase)	P00648	H45K, T46L, E47S	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.	16499867	CPAD
P-1906	KSEAQVINTFDGVADYLQTYHK	22	Amyloid	Ribonuclease (Barnase)	P00648	H45K, T46S	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.	16499867	CPAD
P-1907	LGVVGSTTTQLYTDSTEKLRPE	22	Amyloid	Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3)	Q15582	R124S	Eur J Biochem. 2002 Nov;269(21):5149-56.	12392546	CPAD
P-1908	LLSAQVINTFDGVADYLQTYHK	22	Amyloid	Ribonuclease (Barnase)	P00648	H45L, T46L, E47S	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.	16499867	CPAD
P-1909	SLEAQVINTFDGVADYLQTYHK	22	Amyloid	Ribonuclease (Barnase)	P00648	H45S, T46L	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.	16499867	CPAD
P-1910	SLSAQVINTFDGVADYLQTYHK	22	Amyloid	Ribonuclease (Barnase)	P00648	H45S, T46L, E47S	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.	16499867	CPAD
P-1911	SNFLNCYVSGFHPSDIEVDLLK	22	Amyloid	Beta-2-microglobulin	P61769	No	Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4074-8.	16537487	CPAD, AmyLoad
P-1912	VPSNEEQIKKLLELEAKKHLQY	22	Non-amyloid				J Mol Biol. 1996 Jan 26;255(3):507-21.	8568894	AmyLoad
P-1913	VPSNEEQIKNLLQLEAQEHLQY	22	Non-amyloid				J Mol Biol. 1996 Jan 26;255(3):507-21.	8568894	AmyLoad
P-1914	DSGYEVHHQKLVFFAEDVGSNKG	23	Amyloid	Amyloid-beta precursor protein (APP)	P05067	No	Biochemistry. 1995 Jan 24;34(3):724-30; J Biol Chem. 2002 Nov 8;277(45):43243-6.	7827029 1	CPAD, AmyLoad
P-1915	GTGNTEKMAELIAKGIIESGKDY	23	Non-amyloid	Flavodoxin	P00322	V30Y	J Mol Biol. 1995 Apr 7;247(4):648-69.	7723021	AmyLoad
P-1916	INNTKSFEDIHQYREQIKRVKDS	23	Non-amyloid	GTPase HRas (H-Ras-1) (Transforming protein p21)	P08642		J Mol Biol. 1995 Apr 7;247(4):648-69.	7723021	AmyLoad
P-1917	KSSTEEKYNEKGELSEKKITRAD	23	Amyloid	Outer surface protein A	P0CL66		J Mol Biol. 2000 Aug 11;301(2):477-89.	10926522	CPAD
P-1918	QNNFVHDCVNITIKQHTVTTTTK	23	Amyloid	Major prion protein (PrP)	P04156	No	Biochemistry. 2008 Dec 16;47(50):13242-51.	19053276	CPAD
P-1919	AEAIGNVAVAGELPVAGKTAVAGR	24	Amyloid				Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4074-8.	16537487	CPAD
P-1920	GAAVPGVLGGLGALGGVGIPGGVV	24	Amyloid	Elastin (Tropoelastin)	P15502	No	Biomacromolecules. 2007 Nov;8(11):3478-86.	17929969	CPAD

Peptide details

Entry:	P-1891
Peptide:	QTAPVPMPDLKNVKSKIGSTE
Length:	21
Classification:	Non-amyloid
Mutation(s):
Structure(s):	No structures

Protein Information

UniProt ID:	P10636
UniProt Name:	TAU_HUMAN
Protein Name:	Microtubule-associated protein tau (PHF-tau)
Position:

Literature

PMID:	10805776
Reference:	Proc Natl Acad Sci U S A. 2000 May 9;97(10):5129-34.
source:	AmyLoad

Derived Information

Net Charge:	1
Absolute Charge:	5
Hydrophobicity:	42.86
NuAPRpred:	-6.04
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-18.5
Area of the profile Above Threshold (AGGRESCAN):	0.67
Best Energy Score (PASTA 2.0):	-1.4
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

L

P

G

L

A

L

A

W

T

A

R

A

L

E

V

P

T

D

G

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A

G

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A

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A

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M

N

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Q

N

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S

D

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S

G

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60

61

T

C

I

D

T

K

E

G

I

L

Q

Y

C

Q

E

V

Y

P

E

L

Q

I

T

N

V

E

A

N

Q

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T

I

Q

N

W

C

K

R

G

R

K

Q

C

K

T

H

P

H

F

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I

P

Y

R

C

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V

G

120

121

E

F

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A

L

V

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C

K

F

L

H

Q

E

R

M

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V

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T

H

L

H

W

H

T

V

A

K

E

T

C

S

E

K

S

T

N

L

H

D

Y

G

M

L

P

C

G

I

D

K

F

R

180

181

G

V

E

F

V

C

P

L

A

E

S

D

N

V

D

S

A

D

A

E

D

S

D

V

W

G

A

D

T

D

Y

A

D

G

S

E

D

K

V

E

V

A

E

V

A

E

V

E

240

241

E

A

D

E

D

E

D

G

D

E

V

E

A

E

P

Y

E

A

T

E

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T

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I

A

T

E

S

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E

V

R

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C

S

E

Q

A

E

T

G

P

C

300

301

R

A

M

I

S

R

W

Y

F

D

V

T

E

G

K

C

A

P

F

Y

G

C

G

N

R

N

F

D

T

E

Y

C

M

A

V

C

G

S

A

M

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S

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T

Q

E

P

L

A

R

D

360

361

P

V

K

L

P

T

A

S

T

P

D

A

V

D

K

Y

L

E

T

P

G

D

E

N

E

H

A

H

F

Q

K

A

K

E

R

L

E

A

K

H

R

E

R

M

S

Q

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M

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E

W

E

A

E

R

Q

A

420

421

K

N

L

P

K

A

D

K

A

V

I

Q

H

F

Q

E

K

V

E

S

L

E

Q

E

A

N

E

R

Q

L

V

E

T

H

M

A

R

V

E

A

M

L

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D

R

L

A

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E

N

Y

I

T

A

L

480

481

Q

A

V

P

R

P

R

H

V

F

N

M

L

K

Y

V

R

A

E

Q

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K

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F

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V

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A

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I

R

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V

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H

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V

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Y

E

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540

541

M

N

Q

S

L

S

L

Y

N

V

P

A

V

A

E

I

Q

D

E

V

D

E

L

Q

K

E

Q

N

Y

S

D

V

L

A

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M

I

S

E

P

R

I

S

Y

G

N

D

A

L

M

P

S

L

T

E

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600

601

K

T

V

E

L

P

V

N

G

E

F

S

L

D

L

Q

P

W

H

S

F

G

A

D

S

V

P

A

N

T

E

N

E

V

E

P

V

D

A

R

P

A

D

R

G

L

T

R

P

G

S

G

L

T

N

660

661

I

K

T

E

I

S

E

V

K

M

D

A

E

F

R

H

D

S

G

Y

E

V

H

Q

K

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V

F

A

E

D

V

G

S

N

K

G

A

I

G

L

M

V

G

V

I

A

T

V

I

V

I

T

L

720

721

V

M

L

K

Q

Y

T

S

I

H

G

V

E

V

D

A

V

T

P

E

R

H

L

S

K

M

Q

N

G

Y

E

N

P

T

Y

K

F

E

Q

M

Q

N

770

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1892
Peptide:	SGYEVHHQKLVFFAEDVGSNK
Length:	21
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P05067
UniProt Name:	A4_HUMAN
Protein Name:	Amyloid-beta precursor protein (APP)
Position:	679-699

Literature

PMID:	7827029 1
Reference:	Biochemistry. 1995 Jan 24;34(3):724-30; J Biol Chem. 2002 Nov 8;277(45):43243-6.
source:	CPAD, AmyLoad

Derived Information

Net Charge:	-1
Absolute Charge:	5
Hydrophobicity:	38.1
NuAPRpred:	0.54
Tango:	433.46

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-12.4
Area of the profile Above Threshold (AGGRESCAN):	3.94
Best Energy Score (PASTA 2.0):	-4.54
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

G

T

R

L

P

A

L

F

L

V

L

V

L

G

F

E

V

Q

G

T

Q

P

Q

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E

M

P

S

P

T

F

L

T

Q

V

K

E

S

L

S

Y

W

E

S

A

K

T

A

Q

N

L

Y

E

60

61

K

T

Y

L

P

A

V

D

E

K

L

R

D

L

Y

S

K

S

T

A

M

S

T

Y

T

G

I

F

T

D

Q

V

L

S

V

L

K

G

E

101

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1893
Peptide:	STAAMSTYTGIFTDQVLSVLK
Length:	21
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P02655
UniProt Name:	APOC2_HUMAN
Protein Name:	Apolipoprotein C-II (ApoC-II)
Position:	78-98

Literature

PMID:	17217959
Reference:	J Mol Biol. 2007 Mar 9;366(5):1639-51.
source:	CPAD

Derived Information

Net Charge:	0
Absolute Charge:	2
Hydrophobicity:	47.62
NuAPRpred:	-1.28
Tango:	261.93

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	21.7
Area of the profile Above Threshold (AGGRESCAN):	5.89
Best Energy Score (PASTA 2.0):	-4.88
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

A

N

L

G

C

W

M

L

V

L

F

V

A

T

W

S

D

L

G

L

C

K

R

P

K

P

G

W

N

T

G

S

R

Y

P

G

Q

G

S

P

G

N

R

Y

P

Q

G

W

G

Q

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60

61

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

P

H

G

W

G

Q

G

T

H

S

Q

W

N

K

P

S

K

P

K

T

N

M

K

H

M

A

G

A

G

A

120

121

V

G

L

G

Y

M

L

G

S

A

M

S

R

P

I

H

F

G

S

D

Y

E

D

R

Y

R

E

N

M

H

R

Y

P

N

Q

V

Y

R

P

M

D

E

Y

S

N

Q

N

F

V

H

D

C

V

180

181

N

I

T

I

K

Q

H

T

V

T

K

G

E

N

F

T

E

T

D

V

K

M

E

R

V

E

Q

M

C

I

T

Q

Y

E

R

E

S

Q

A

Y

Q

R

G

S

M

V

L

F

S

P

V

240

241

I

L

I

S

F

L

I

F

L

I

V

G

253

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1894
Peptide:	TNVKHVAGAAAAGAVVGGLGG
Length:	21
Classification:	Amyloid
Mutation(s):	M108V, M111V
Structure(s):	No structures

Protein Information

UniProt ID:	P04156
UniProt Name:	PRIO_HUMAN
Protein Name:	Major prion protein (PrP)
Position:	107-127

Literature

PMID:	18423487
Reference:	J Mol Biol. 2008 May 16;378(5):1142-54.
source:	CPAD

Derived Information

Net Charge:	1
Absolute Charge:	1
Hydrophobicity:	52.38
NuAPRpred:	1.3
Tango:	14.75

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	0.8
Area of the profile Above Threshold (AGGRESCAN):	3.12
Best Energy Score (PASTA 2.0):	-2.65
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

S

D

E

G

R

E

Y

L

F

K

I

V

I

G

D

S

A

V

G

K

S

N

L

S

R

Y

A

R

N

E

F

S

A

N

S

K

A

T

I

G

V

E

F

Q

T

Q

S

M

E

I

E

G

K

E

60

61

V

K

A

Q

I

W

D

T

A

G

Q

E

R

F

R

A

V

T

S

A

Y

R

G

A

V

G

A

L

V

Y

D

I

T

R

T

F

E

S

V

G

R

W

L

D

E

L

K

I

H

S

D

T

V

A

R

120

121

M

L

V

G

N

K

C

D

L

E

N

I

R

A

V

S

V

E

G

K

A

L

A

E

G

L

F

V

E

T

S

A

L

D

S

T

N

V

K

T

A

F

E

M

V

I

L

D

I

Y

N

V

S

R

K

180

181

Q

L

N

S

D

T

Y

K

D

E

L

T

V

N

R

V

S

L

V

K

D

N

S

A

S

K

Q

S

G

F

S

C

S

T

218

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1895
Peptide:	TRRTTFESVGRWLDELKIHSD
Length:	21
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P19892
UniProt Name:	RAA5E_ARATH
Protein Name:	Ras-related protein RABA5e (AtRABA5e) (Ras-related protein Ara-1)
Position:	95-115

Literature

PMID:	8520484
Reference:	Protein Sci. 1995 Aug;4(8):1577-86.
source:	AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	8
Hydrophobicity:	28.57
NuAPRpred:	-4.65
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-21.2
Area of the profile Above Threshold (AGGRESCAN):	1.5
Best Energy Score (PASTA 2.0):	-2.25
Aggregate Orientation (PASTA 2.0):	Antiparallel

Peptide details

Entry:	P-1896
Peptide:	VTIKANLIFANGFTQTAEFKG
Length:	21
Classification:	Amyloid
Mutation(s):
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:	PL B1 protein
Protein Name:
Position:

Literature

PMID:	9007989
Reference:	Protein Sci. 1997 Jan;6(1):162-74.
source:	CPAD, AmyLoad

Derived Information

Net Charge:	1
Absolute Charge:	3
Hydrophobicity:	47.62
NuAPRpred:	-0.63
Tango:	49.8

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	6.5
Area of the profile Above Threshold (AGGRESCAN):	4.28
Best Energy Score (PASTA 2.0):	-5.81
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

G

W

E

I

P

E

P

Y

V

W

D

E

S

F

R

V

F

Y

E

Q

L

D

E

H

K

I

F

K

G

I

F

D

C

I

R

D

N

S

A

P

N

L

A

T

L

V

K

V

T

N

H

F

T

H

E

A

60

61

M

D

A

K

Y

S

E

V

P

H

K

M

H

K

D

F

L

E

K

I

G

L

S

A

P

V

D

A

K

N

V

D

Y

C

K

E

W

L

V

N

H

I

K

G

T

D

F

K

Y

K

G

K

L

118

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1897
Peptide:	YEQLDEEHKKIFKGIFDCIRD
Length:	21
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P02247
UniProt Name:	HEMTM_THEHE
Protein Name:	Myohemerythrin (MHr)
Position:	18-38

Literature

PMID:	1507227
Reference:	J Mol Biol. 1992 Aug 5;226(3):795-817.
source:	CPAD, AmyLoad

Derived Information

Net Charge:	-2
Absolute Charge:	10
Hydrophobicity:	38.1
NuAPRpred:	0.03
Tango:	8.05

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-20.7
Area of the profile Above Threshold (AGGRESCAN):	3.74
Best Energy Score (PASTA 2.0):	-3.61
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

S

N

V

P

H

K

S

L

P

E

G

I

R

P

G

T

V

L

R

I

R

G

L

V

P

N

A

S

R

F

H

V

N

L

C

G

E

Q

G

S

D

A

L

H

F

N

P

R

L

D

T

S

E

V

60

61

V

F

N

S

K

E

Q

G

S

W

G

R

E

R

G

P

G

V

P

F

Q

R

G

Q

P

F

E

V

L

I

A

S

D

G

F

K

A

V

G

D

A

Q

Y

H

F

R

H

R

L

P

L

A

R

V

R

120

121

L

V

E

V

G

D

V

Q

L

D

S

V

R

I

F

136

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1898
Peptide:	DAALHFNPRLDTSEVVFNSKEQ
Length:	22
Classification:	Non-amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P47929
UniProt Name:	LEG7_HUMAN
Protein Name:	Galectin-7
Position:	46-67

Literature

PMID:	25172508
Reference:	J Biol Chem. 2014 Oct 17;289(42):29195-207
source:	CPAD

Derived Information

Net Charge:	-2
Absolute Charge:	6
Hydrophobicity:	40.91
NuAPRpred:	-4.64
Tango:	3.41

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-20.8
Area of the profile Above Threshold (AGGRESCAN):	3.0
Best Energy Score (PASTA 2.0):	-4.88
Aggregate Orientation (PASTA 2.0):	-

Peptide details

Entry:	P-1899
Peptide:	DDNNQQNYQQYSQNGNQQQGKK
Length:	22
Classification:	Amyloid
Mutation(s):
Structure(s):	No structures

Protein Information

UniProt ID:	P05453
UniProt Name:	ERF3_YEAST
Protein Name:	Eukaryotic peptide chain release factor GTP-binding subunit (ERF-3)
Position:

Literature

PMID:	11960014
Reference:	Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5591-5.
source:	CPAD

Derived Information

Net Charge:	0
Absolute Charge:	4
Hydrophobicity:	9.09
NuAPRpred:	-5.15
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-94.9
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	-1.09
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

K

M

E

G

I

A

L

K

R

L

S

W

I

S

V

C

L

V

L

V

S

A

G

M

L

F

S

T

A

K

T

E

T

S

H

K

A

H

T

E

A

Q

V

I

N

T

F

D

G

V

A

D

Y

60

61

L

Q

T

Y

H

K

L

P

D

N

Y

I

T

K

S

E

A

Q

A

L

G

W

V

A

S

K

G

N

L

A

D

V

A

P

G

K

S

I

G

D

I

F

S

N

R

E

G

K

L

P

G

K

S

G

R

T

W

R

E

120

121

A

D

I

N

Y

T

S

G

F

R

N

S

D

R

I

L

Y

S

D

W

L

I

Y

K

T

D

H

Y

Q

T

F

T

K

I

R

157

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1900
Peptide:	ELEAQVINTFDGVADYLQTYHK
Length:	22
Classification:	Amyloid
Mutation(s):	H45E, T46L
Structure(s):	No structures

Protein Information

UniProt ID:	P00648
UniProt Name:	RNBR_BACAM
Protein Name:	Ribonuclease (Barnase)
Position:	45-66

Literature

PMID:	16499867
Reference:	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.
source:	CPAD

Derived Information

Net Charge:	-3
Absolute Charge:	5
Hydrophobicity:	45.45
NuAPRpred:	-1.69
Tango:	6.5

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-7.1
Area of the profile Above Threshold (AGGRESCAN):	2.92
Best Energy Score (PASTA 2.0):	-4.92
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

K

M

E

G

I

A

L

K

R

L

S

W

I

S

V

C

L

V

L

V

S

A

G

M

L

F

S

T

A

K

T

E

T

S

H

K

A

H

T

E

A

Q

V

I

N

T

F

D

G

V

A

D

Y

60

61

L

Q

T

Y

H

K

L

P

D

N

Y

I

T

K

S

E

A

Q

A

L

G

W

V

A

S

K

G

N

L

A

D

V

A

P

G

K

S

I

G

D

I

F

S

N

R

E

G

K

L

P

G

K

S

G

R

T

W

R

E

120

121

A

D

I

N

Y

T

S

G

F

R

N

S

D

R

I

L

Y

S

D

W

L

I

Y

K

T

D

H

Y

Q

T

F

T

K

I

R

157

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1901
Peptide:	ELSAQVINTFDGVADYLQTYHK
Length:	22
Classification:	Amyloid
Mutation(s):	H45E, T46L, E47S
Structure(s):	No structures

Protein Information

UniProt ID:	P00648
UniProt Name:	RNBR_BACAM
Protein Name:	Ribonuclease (Barnase)
Position:	45-66

Literature

PMID:	16499867
Reference:	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.
source:	CPAD

Derived Information

Net Charge:	-2
Absolute Charge:	4
Hydrophobicity:	45.45
NuAPRpred:	-2.06
Tango:	11.5

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-2.0
Area of the profile Above Threshold (AGGRESCAN):	3.36
Best Energy Score (PASTA 2.0):	-4.92
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

K

M

E

G

I

A

L

K

R

L

S

W

I

S

V

C

L

V

L

V

S

A

G

M

L

F

S

T

A

K

T

E

T

S

H

K

A

H

T

E

A

Q

V

I

N

T

F

D

G

V

A

D

Y

60

61

L

Q

T

Y

H

K

L

P

D

N

Y

I

T

K

S

E

A

Q

A

L

G

W

V

A

S

K

G

N

L

A

D

V

A

P

G

K

S

I

G

D

I

F

S

N

R

E

G

K

L

P

G

K

S

G

R

T

W

R

E

120

121

A

D

I

N

Y

T

S

G

F

R

N

S

D

R

I

L

Y

S

D

W

L

I

Y

K

T

D

H

Y

Q

T

F

T

K

I

R

157

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1902
Peptide:	ESLAQVINTFDGVADYLQTYHK
Length:	22
Classification:	Amyloid
Mutation(s):	H45E, T46S, E47L
Structure(s):	No structures

Protein Information

UniProt ID:	P00648
UniProt Name:	RNBR_BACAM
Protein Name:	Ribonuclease (Barnase)
Position:	45-66

Literature

PMID:	16499867
Reference:	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.
source:	CPAD

Derived Information

Net Charge:	-2
Absolute Charge:	4
Hydrophobicity:	45.45
NuAPRpred:	-1.46
Tango:	26.99

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-0.5
Area of the profile Above Threshold (AGGRESCAN):	3.7
Best Energy Score (PASTA 2.0):	-4.92
Aggregate Orientation (PASTA 2.0):	Parallel

Peptide details

Entry:	P-1903
Peptide:	GTVSFVTSPHQGAGMVGKVTVN
Length:	22
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:	PLAS_PHAVU
Protein Name:
Position:

Literature

PMID:	1507227
Reference:	J Mol Biol. 1992 Aug 5;226(3):795-817.
source:	CPAD, AmyLoad

Derived Information

Net Charge:	1
Absolute Charge:	1
Hydrophobicity:	40.91
NuAPRpred:	-3.55
Tango:	107.66

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	9.9
Area of the profile Above Threshold (AGGRESCAN):	5.81
Best Energy Score (PASTA 2.0):	-4.39
Aggregate Orientation (PASTA 2.0):	Parallel

Peptide details

Entry:	P-1904
Peptide:	KDRVQSKIGSLDNITHVPGGGN
Length:	22
Classification:	Non-amyloid
Mutation(s):
Structure(s):	No structures

Protein Information

UniProt ID:	P10636
UniProt Name:	TAU_HUMAN
Protein Name:	Microtubule-associated protein tau (PHF-tau)
Position:

Literature

PMID:	10805776
Reference:	Proc Natl Acad Sci U S A. 2000 May 9;97(10):5129-34.
source:	AmyLoad

Derived Information

Net Charge:	1
Absolute Charge:	5
Hydrophobicity:	27.27
NuAPRpred:	-6.15
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-28.0
Area of the profile Above Threshold (AGGRESCAN):	1.25
Best Energy Score (PASTA 2.0):	-3.97
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

K

M

E

G

I

A

L

K

R

L

S

W

I

S

V

C

L

V

L

V

S

A

G

M

L

F

S

T

A

K

T

E

T

S

H

K

A

H

T

E

A

Q

V

I

N

T

F

D

G

V

A

D

Y

60

61

L

Q

T

Y

H

K

L

P

D

N

Y

I

T

K

S

E

A

Q

A

L

G

W

V

A

S

K

G

N

L

A

D

V

A

P

G

K

S

I

G

D

I

F

S

N

R

E

G

K

L

P

G

K

S

G

R

T

W

R

E

120

121

A

D

I

N

Y

T

S

G

F

R

N

S

D

R

I

L

Y

S

D

W

L

I

Y

K

T

D

H

Y

Q

T

F

T

K

I

R

157

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1905
Peptide:	KLSAQVINTFDGVADYLQTYHK
Length:	22
Classification:	Amyloid
Mutation(s):	H45K, T46L, E47S
Structure(s):	No structures

Protein Information

UniProt ID:	P00648
UniProt Name:	RNBR_BACAM
Protein Name:	Ribonuclease (Barnase)
Position:	45-66

Literature

PMID:	16499867
Reference:	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.
source:	CPAD

Derived Information

Net Charge:	0
Absolute Charge:	4
Hydrophobicity:	45.45
NuAPRpred:	-2.23
Tango:	10.34

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-0.7
Area of the profile Above Threshold (AGGRESCAN):	3.36
Best Energy Score (PASTA 2.0):	-4.92
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

K

M

E

G

I

A

L

K

R

L

S

W

I

S

V

C

L

V

L

V

S

A

G

M

L

F

S

T

A

K

T

E

T

S

H

K

A

H

T

E

A

Q

V

I

N

T

F

D

G

V

A

D

Y

60

61

L

Q

T

Y

H

K

L

P

D

N

Y

I

T

K

S

E

A

Q

A

L

G

W

V

A

S

K

G

N

L

A

D

V

A

P

G

K

S

I

G

D

I

F

S

N

R

E

G

K

L

P

G

K

S

G

R

T

W

R

E

120

121

A

D

I

N

Y

T

S

G

F

R

N

S

D

R

I

L

Y

S

D

W

L

I

Y

K

T

D

H

Y

Q

T

F

T

K

I

R

157

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1906
Peptide:	KSEAQVINTFDGVADYLQTYHK
Length:	22
Classification:	Amyloid
Mutation(s):	H45K, T46S
Structure(s):	No structures

Protein Information

UniProt ID:	P00648
UniProt Name:	RNBR_BACAM
Protein Name:	Ribonuclease (Barnase)
Position:	45-66

Literature

PMID:	16499867
Reference:	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.
source:	CPAD

Derived Information

Net Charge:	-1
Absolute Charge:	5
Hydrophobicity:	40.91
NuAPRpred:	-2.88
Tango:	6.68

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-11.9
Area of the profile Above Threshold (AGGRESCAN):	2.84
Best Energy Score (PASTA 2.0):	-4.92
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

A

L

F

V

R

L

A

L

A

L

A

L

A

L

G

P

A

T

L

A

G

P

A

K

S

P

Y

Q

L

V

L

Q

H

S

R

L

R

G

R

Q

H

G

P

N

V

C

A

V

Q

K

V

I

G

T

N

R

K

60

61

Y

F

T

N

C

K

Q

W

Y

Q

R

K

I

C

G

K

S

T

V

I

S

Y

E

C

P

G

Y

E

K

V

P

G

E

K

G

C

P

A

L

P

L

S

N

L

Y

E

T

L

G

V

G

S

T

Q

L

120

121

Y

T

D

R

T

E

K

L

R

P

E

M

E

G

P

G

S

F

T

I

F

A

P

S

N

E

A

W

A

S

L

P

A

E

V

L

D

S

L

V

S

N

V

N

I

E

L

N

A

L

R

Y

H

M

V

G

R

V

180

181

L

T

D

E

L

K

H

G

M

T

L

T

S

M

Y

Q

N

S

N

I

Q

I

H

Y

P

N

G

I

V

T

V

N

C

A

R

L

K

A

D

H

A

T

N

G

V

H

L

I

D

K

V

I

S

T

I

T

240

241

N

I

Q

I

E

I

E

D

T

F

E

T

L

R

A

V

A

S

G

L

N

T

M

L

E

G

N

G

Q

Y

T

L

A

P

T

N

E

A

F

E

K

I

P

S

E

T

L

N

R

I

L

G

D

P

300

301

E

A

L

R

D

L

N

H

I

L

K

S

A

M

C

A

E

A

I

V

A

G

L

S

V

E

T

L

E

G

T

L

E

V

G

C

S

G

D

M

L

T

I

N

G

K

A

I

S

N

K

D

I

L

A

T

360

361

N

G

V

I

H

Y

I

D

E

L

I

P

D

S

A

K

T

L

F

E

L

A

E

S

D

V

S

T

A

I

D

L

F

R

Q

A

G

L

G

N

H

L

S

G

S

E

R

L

T

L

A

P

L

N

S

V

F

420

421

K

D

G

T

P

I

D

A

H

T

R

N

L

R

N

H

I

K

D

Q

L

A

S

K

Y

L

Y

H

G

Q

T

L

E

T

L

G

K

L

R

V

F

V

Y

R

N

S

L

C

I

E

N

S

C

I

A

480

481

A

H

D

K

R

G

R

Y

G

T

L

F

T

M

D

R

V

L

T

P

M

G

T

V

M

D

V

L

K

G

D

N

R

F

S

M

L

V

A

I

Q

S

A

G

L

T

E

T

L

N

R

E

G

V

Y

T

V

F

540

541

A

P

T

N

E

A

F

R

A

L

P

R

E

R

S

R

L

G

D

A

K

E

L

A

N

I

L

K

Y

H

I

G

D

E

I

L

V

S

G

I

G

A

L

V

R

L

K

S

L

Q

G

D

K

L

E

V

S

600

601

L

K

N

V

S

V

N

K

E

P

V

A

E

P

D

I

M

A

T

N

G

V

H

V

I

T

N

V

L

Q

P

A

N

R

P

Q

E

R

G

D

E

L

A

D

S

A

L

E

I

F

K

Q

A

S

A

F

660

661

S

R

A

S

Q

R

S

V

R

L

A

P

V

Y

Q

K

L

E

R

M

K

H

683

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1907
Peptide:	LGVVGSTTTQLYTDSTEKLRPE
Length:	22
Classification:	Amyloid
Mutation(s):	R124S
Structure(s):	No structures

Protein Information

UniProt ID:	Q15582
UniProt Name:	BGH3_HUMAN
Protein Name:	Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3)
Position:	110-131

Literature

PMID:	12392546
Reference:	Eur J Biochem. 2002 Nov;269(21):5149-56.
source:	CPAD

Derived Information

Net Charge:	-1
Absolute Charge:	5
Hydrophobicity:	31.82
NuAPRpred:	-6.11
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-12.1
Area of the profile Above Threshold (AGGRESCAN):	3.43
Best Energy Score (PASTA 2.0):	-3.43
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

K

M

E

G

I

A

L

K

R

L

S

W

I

S

V

C

L

V

L

V

S

A

G

M

L

F

S

T

A

K

T

E

T

S

H

K

A

H

T

E

A

Q

V

I

N

T

F

D

G

V

A

D

Y

60

61

L

Q

T

Y

H

K

L

P

D

N

Y

I

T

K

S

E

A

Q

A

L

G

W

V

A

S

K

G

N

L

A

D

V

A

P

G

K

S

I

G

D

I

F

S

N

R

E

G

K

L

P

G

K

S

G

R

T

W

R

E

120

121

A

D

I

N

Y

T

S

G

F

R

N

S

D

R

I

L

Y

S

D

W

L

I

Y

K

T

D

H

Y

Q

T

F

T

K

I

R

157

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1908
Peptide:	LLSAQVINTFDGVADYLQTYHK
Length:	22
Classification:	Amyloid
Mutation(s):	H45L, T46L, E47S
Structure(s):	No structures

Protein Information

UniProt ID:	P00648
UniProt Name:	RNBR_BACAM
Protein Name:	Ribonuclease (Barnase)
Position:	45-66

Literature

PMID:	16499867
Reference:	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.
source:	CPAD

Derived Information

Net Charge:	-1
Absolute Charge:	3
Hydrophobicity:	50.0
NuAPRpred:	-1.55
Tango:	10.4

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	5.6
Area of the profile Above Threshold (AGGRESCAN):	4.08
Best Energy Score (PASTA 2.0):	-4.92
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

K

M

E

G

I

A

L

K

R

L

S

W

I

S

V

C

L

V

L

V

S

A

G

M

L

F

S

T

A

K

T

E

T

S

H

K

A

H

T

E

A

Q

V

I

N

T

F

D

G

V

A

D

Y

60

61

L

Q

T

Y

H

K

L

P

D

N

Y

I

T

K

S

E

A

Q

A

L

G

W

V

A

S

K

G

N

L

A

D

V

A

P

G

K

S

I

G

D

I

F

S

N

R

E

G

K

L

P

G

K

S

G

R

T

W

R

E

120

121

A

D

I

N

Y

T

S

G

F

R

N

S

D

R

I

L

Y

S

D

W

L

I

Y

K

T

D

H

Y

Q

T

F

T

K

I

R

157

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1909
Peptide:	SLEAQVINTFDGVADYLQTYHK
Length:	22
Classification:	Amyloid
Mutation(s):	H45S, T46L
Structure(s):	No structures

Protein Information

UniProt ID:	P00648
UniProt Name:	RNBR_BACAM
Protein Name:	Ribonuclease (Barnase)
Position:	45-66

Literature

PMID:	16499867
Reference:	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.
source:	CPAD

Derived Information

Net Charge:	-2
Absolute Charge:	4
Hydrophobicity:	45.45
NuAPRpred:	-1.96
Tango:	5.83

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-4.0
Area of the profile Above Threshold (AGGRESCAN):	2.92
Best Energy Score (PASTA 2.0):	-4.92
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

K

M

E

G

I

A

L

K

R

L

S

W

I

S

V

C

L

V

L

V

S

A

G

M

L

F

S

T

A

K

T

E

T

S

H

K

A

H

T

E

A

Q

V

I

N

T

F

D

G

V

A

D

Y

60

61

L

Q

T

Y

H

K

L

P

D

N

Y

I

T

K

S

E

A

Q

A

L

G

W

V

A

S

K

G

N

L

A

D

V

A

P

G

K

S

I

G

D

I

F

S

N

R

E

G

K

L

P

G

K

S

G

R

T

W

R

E

120

121

A

D

I

N

Y

T

S

G

F

R

N

S

D

R

I

L

Y

S

D

W

L

I

Y

K

T

D

H

Y

Q

T

F

T

K

I

R

157

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1910
Peptide:	SLSAQVINTFDGVADYLQTYHK
Length:	22
Classification:	Amyloid
Mutation(s):	H45S, T46L, E47S
Structure(s):	No structures

Protein Information

UniProt ID:	P00648
UniProt Name:	RNBR_BACAM
Protein Name:	Ribonuclease (Barnase)
Position:	45-66

Literature

PMID:	16499867
Reference:	Biochem Biophys Res Commun. 2006 Apr 14;342(3):808-16.
source:	CPAD

Derived Information

Net Charge:	-1
Absolute Charge:	3
Hydrophobicity:	45.45
NuAPRpred:	-2.14
Tango:	9.46

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	1.0
Area of the profile Above Threshold (AGGRESCAN):	3.36
Best Energy Score (PASTA 2.0):	-4.92
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

S

R

S

V

A

L

A

V

L

A

L

S

L

S

G

L

E

A

I

Q

R

T

P

K

I

Q

V

Y

S

R

H

P

A

E

N

G

K

S

N

F

L

N

C

Y

V

S

G

F

H

P

S

D

I

E

V

D

L

60

61

K

N

G

E

R

I

E

K

V

E

H

S

D

L

S

F

S

K

D

W

S

F

Y

L

Y

T

E

F

T

P

T

E

K

D

E

Y

A

C

R

V

N

H

V

T

L

S

Q

P

K

I

V

K

W

D

R

D

M

119

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1911
Peptide:	SNFLNCYVSGFHPSDIEVDLLK
Length:	22
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P61769
UniProt Name:	B2MG_HUMAN
Protein Name:	Beta-2-microglobulin
Position:	40-61

Literature

PMID:	16537487
Reference:	Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4074-8.
source:	CPAD, AmyLoad

Derived Information

Net Charge:	-2
Absolute Charge:	4
Hydrophobicity:	50.0
NuAPRpred:	2.12
Tango:	13.76

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	10.5
Area of the profile Above Threshold (AGGRESCAN):	4.65
Best Energy Score (PASTA 2.0):	-4.13
Aggregate Orientation (PASTA 2.0):	Parallel

Peptide details

Entry:	P-1912
Peptide:	VPSNEEQIKKLLELEAKKHLQY
Length:	22
Classification:	Non-amyloid
Mutation(s):
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:
Protein Name:
Position:

Literature

PMID:	8568894
Reference:	J Mol Biol. 1996 Jan 26;255(3):507-21.
source:	AmyLoad

Derived Information

Net Charge:	0
Absolute Charge:	8
Hydrophobicity:	40.91
NuAPRpred:	-0.72
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-32.2
Area of the profile Above Threshold (AGGRESCAN):	1.27
Best Energy Score (PASTA 2.0):	-1.12
Aggregate Orientation (PASTA 2.0):	Antiparallel

Peptide details

Entry:	P-1913
Peptide:	VPSNEEQIKNLLQLEAQEHLQY
Length:	22
Classification:	Non-amyloid
Mutation(s):
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:
Protein Name:
Position:

Literature

PMID:	8568894
Reference:	J Mol Biol. 1996 Jan 26;255(3):507-21.
source:	AmyLoad

Derived Information

Net Charge:	-3
Absolute Charge:	5
Hydrophobicity:	40.91
NuAPRpred:	0.28
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-36.6
Area of the profile Above Threshold (AGGRESCAN):	1.19
Best Energy Score (PASTA 2.0):	-2.12
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

L

P

G

L

A

L

A

W

T

A

R

A

L

E

V

P

T

D

G

N

A

G

L

A

E

P

Q

I

A

M

F

C

G

R

L

N

M

H

M

N

V

Q

N

G

K

W

D

S

D

P

S

G

T

K

60

61

T

C

I

D

T

K

E

G

I

L

Q

Y

C

Q

E

V

Y

P

E

L

Q

I

T

N

V

E

A

N

Q

P

V

T

I

Q

N

W

C

K

R

G

R

K

Q

C

K

T

H

P

H

F

V

I

P

Y

R

C

L

V

G

120

121

E

F

V

S

D

A

L

V

P

D

K

C

K

F

L

H

Q

E

R

M

D

V

C

E

T

H

L

H

W

H

T

V

A

K

E

T

C

S

E

K

S

T

N

L

H

D

Y

G

M

L

P

C

G

I

D

K

F

R

180

181

G

V

E

F

V

C

P

L

A

E

S

D

N

V

D

S

A

D

A

E

D

S

D

V

W

G

A

D

T

D

Y

A

D

G

S

E

D

K

V

E

V

A

E

V

A

E

V

E

240

241

E

A

D

E

D

E

D

G

D

E

V

E

A

E

P

Y

E

A

T

E

R

T

S

I

A

T

E

S

V

E

V

R

E

V

C

S

E

Q

A

E

T

G

P

C

300

301

R

A

M

I

S

R

W

Y

F

D

V

T

E

G

K

C

A

P

F

Y

G

C

G

N

R

N

F

D

T

E

Y

C

M

A

V

C

G

S

A

M

S

Q

S

L

K

T

Q

E

P

L

A

R

D

360

361

P

V

K

L

P

T

A

S

T

P

D

A

V

D

K

Y

L

E

T

P

G

D

E

N

E

H

A

H

F

Q

K

A

K

E

R

L

E

A

K

H

R

E

R

M

S

Q

V

M

R

E

W

E

A

E

R

Q

A

420

421

K

N

L

P

K

A

D

K

A

V

I

Q

H

F

Q

E

K

V

E

S

L

E

Q

E

A

N

E

R

Q

L

V

E

T

H

M

A

R

V

E

A

M

L

N

D

R

L

A

L

E

N

Y

I

T

A

L

480

481

Q

A

V

P

R

P

R

H

V

F

N

M

L

K

Y

V

R

A

E

Q

K

D

R

Q

H

T

L

K

H

F

E

H

V

R

M

V

D

P

K

A

Q

I

R

S

Q

V

M

T

H

L

R

V

I

Y

E

R

540

541

M

N

Q

S

L

S

L

Y

N

V

P

A

V

A

E

I

Q

D

E

V

D

E

L

Q

K

E

Q

N

Y

S

D

V

L

A

N

M

I

S

E

P

R

I

S

Y

G

N

D

A

L

M

P

S

L

T

E

T

600

601

K

T

V

E

L

P

V

N

G

E

F

S

L

D

L

Q

P

W

H

S

F

G

A

D

S

V

P

A

N

T

E

N

E

V

E

P

V

D

A

R

P

A

D

R

G

L

T

R

P

G

S

G

L

T

N

660

661

I

K

T

E

I

S

E

V

K

M

D

A

E

F

R

H

D

S

G

Y

E

V

H

Q

K

L

V

F

A

E

D

V

G

S

N

K

G

A

I

G

L

M

V

G

V

I

A

T

V

I

V

I

T

L

720

721

V

M

L

K

Q

Y

T

S

I

H

G

V

E

V

D

A

V

T

P

E

R

H

L

S

K

M

Q

N

G

Y

E

N

P

T

Y

K

F

E

Q

M

Q

N

770

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1914
Peptide:	DSGYEVHHQKLVFFAEDVGSNKG
Length:	23
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P05067
UniProt Name:	A4_HUMAN
Protein Name:	Amyloid-beta precursor protein (APP)
Position:	678-700

Literature

PMID:	7827029 1
Reference:	Biochemistry. 1995 Jan 24;34(3):724-30; J Biol Chem. 2002 Nov 8;277(45):43243-6.
source:	CPAD, AmyLoad

Derived Information

Net Charge:	-2
Absolute Charge:	6
Hydrophobicity:	34.78
NuAPRpred:	-0.19
Tango:	433.6

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-17.7
Area of the profile Above Threshold (AGGRESCAN):	3.94
Best Energy Score (PASTA 2.0):	-4.54
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

K

I

V

Y

W

S

G

T

G

N

T

E

K

M

A

E

L

I

A

K

G

I

E

S

G

K

D

V

N

T

I

N

V

S

D

V

N

I

D

E

L

N

E

D

I

L

I

L

G

C

S

A

M

G

D

E

V

60

61

L

E

S

E

F

E

P

F

I

E

I

S

T

K

I

S

G

K

V

A

L

F

G

S

Y

G

W

G

D

G

K

W

M

R

D

F

E

R

M

N

G

Y

G

C

V

E

T

P

L

I

V

Q

N

E

120

121

P

D

E

A

E

Q

D

C

I

E

F

G

K

I

A

N

I

138

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1915
Peptide:	GTGNTEKMAELIAKGIIESGKDY
Length:	23
Classification:	Non-amyloid
Mutation(s):	V30Y
Structure(s):	No structures

Protein Information

UniProt ID:	P00322
UniProt Name:	FLAV_CLOBE
Protein Name:	Flavodoxin
Position:	8-30

Literature

PMID:	7723021
Reference:	J Mol Biol. 1995 Apr 7;247(4):648-69.
source:	AmyLoad

Derived Information

Net Charge:	-1
Absolute Charge:	7
Hydrophobicity:	34.78
NuAPRpred:	-3.98
Tango:	1.14

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-23.4
Area of the profile Above Threshold (AGGRESCAN):	3.13
Best Energy Score (PASTA 2.0):	-3.5
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

T

E

Y

K

L

V

G

A

G

V

G

K

S

A

L

T

I

Q

L

I

Q

N

H

F

V

D

E

Y

D

P

T

I

E

D

S

Y

R

K

Q

V

I

D

G

E

T

C

L

D

I

L

D

T

A

G

60

61

Q

E

Y

S

A

M

R

D

Q

Y

M

R

T

G

E

G

F

L

C

V

F

A

I

N

T

K

S

F

E

D

I

H

Q

Y

R

E

Q

I

K

R

V

K

D

S

D

V

P

M

V

L

V

G

N

K

C

D

L

120

121

P

A

R

T

V

E

T

R

Q

A

Q

D

L

A

R

S

Y

G

I

P

Y

I

E

T

S

A

K

T

R

Q

G

V

E

D

A

F

Y

T

L

V

R

E

I

R

Q

H

K

L

R

K

L

N

P

D

E

S

G

P

G

180

181

C

M

N

C

K

C

V

I

S

189

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1916
Peptide:	INNTKSFEDIHQYREQIKRVKDS
Length:	23
Classification:	Non-amyloid
Mutation(s):
Structure(s):	No structures

Protein Information

UniProt ID:	P08642
UniProt Name:	RASH_CHICK
Protein Name:	GTPase HRas (H-Ras-1) (Transforming protein p21)
Position:	84-106

Literature

PMID:	7723021
Reference:	J Mol Biol. 1995 Apr 7;247(4):648-69.
source:	AmyLoad

Derived Information

Net Charge:	1
Absolute Charge:	9
Hydrophobicity:	26.09
NuAPRpred:	-6.26
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-41.0
Area of the profile Above Threshold (AGGRESCAN):	0.13
Best Energy Score (PASTA 2.0):	-2.77
Aggregate Orientation (PASTA 2.0):	Antiparallel

Peptide details

Entry:	P-1917
Peptide:	KSSTEEKYNEKGELSEKKITRAD
Length:	23
Classification:	Amyloid
Mutation(s):
Structure(s):	No structures

Protein Information

UniProt ID:	P0CL66
UniProt Name:	OSPA_BORBU
Protein Name:	Outer surface protein A
Position:

Literature

PMID:	10926522
Reference:	J Mol Biol. 2000 Aug 11;301(2):477-89.
source:	CPAD

Derived Information

Net Charge:	0
Absolute Charge:	12
Hydrophobicity:	17.39
NuAPRpred:	-6.96
Tango:	0.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-58.6
Area of the profile Above Threshold (AGGRESCAN):	0.0
Best Energy Score (PASTA 2.0):	-1.4
Aggregate Orientation (PASTA 2.0):	Antiparallel

Sequence

1

M

A

N

L

G

Y

W

L

A

L

F

V

T

M

W

T

D

V

G

L

C

K

R

P

K

P

G

W

N

T

G

S

R

Y

P

G

Q

G

S

P

G

N

R

Y

P

Q

G

T

W

G

Q

P

H

60

61

G

W

G

Q

P

H

G

S

W

G

Q

P

H

G

S

W

G

Q

P

H

G

W

G

Q

G

T

H

N

Q

W

N

K

P

S

K

P

K

T

N

L

K

H

V

A

G

A

G

A

V

120

121

V

G

L

G

Y

M

L

G

S

A

M

S

R

P

M

I

H

F

G

N

D

W

E

D

R

Y

R

E

N

M

Y

R

Y

P

N

Q

V

Y

R

P

V

D

Q

Y

S

N

Q

N

F

V

H

D

C

V

N

180

181

I

T

I

K

Q

H

T

V

T

K

G

E

N

F

T

E

T

D

V

K

M

E

R

V

E

Q

M

C

V

T

Q

Y

Q

K

E

S

Q

A

Y

D

G

R

S

T

V

L

F

S

P

240

241

V

I

L

I

S

F

L

I

F

L

I

V

G

254

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1918
Peptide:	QNNFVHDCVNITIKQHTVTTTTK
Length:	23
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P04156
UniProt Name:	PRIO_MOUSE
Protein Name:	Major prion protein (PrP)
Position:	171-193

Literature

PMID:	19053276
Reference:	Biochemistry. 2008 Dec 16;47(50):13242-51.
source:	CPAD

Derived Information

Net Charge:	1
Absolute Charge:	3
Hydrophobicity:	30.43
NuAPRpred:	1.83
Tango:	38.26

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	-8.3
Area of the profile Above Threshold (AGGRESCAN):	2.96
Best Energy Score (PASTA 2.0):	-7.4
Aggregate Orientation (PASTA 2.0):	Parallel

Peptide details

Entry:	P-1919
Peptide:	AEAIGNVAVAGELPVAGKTAVAGR
Length:	24
Classification:	Amyloid
Mutation(s):
Structure(s):	No structures

Protein Information

UniProt ID:
UniProt Name:	A0A0K2S2V2_BOMMO
Protein Name:
Position:

Literature

PMID:	16537487
Reference:	Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4074-8.
source:	CPAD

Derived Information

Net Charge:	0
Absolute Charge:	4
Hydrophobicity:	58.33
NuAPRpred:	-4.76
Tango:	7.09

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	3.7
Area of the profile Above Threshold (AGGRESCAN):	2.98
Best Energy Score (PASTA 2.0):	-4.12
Aggregate Orientation (PASTA 2.0):	Parallel

Sequence

1

M

A

G

L

T

A

P

R

P

G

V

L

S

I

L

H

P

S

R

P

G

V

P

G

A

I

P

G

V

P

G

V

F

Y

P

G

A

G

L

G

A

L

G

A

L

G

P

G

60

61

K

P

L

K

P

V

P

G

L

A

G

A

G

L

G

A

G

L

G

A

F

P

A

V

T

F

P

G

A

L

V

P

G

V

A

D

A

Y

K

A

K

A

G

A

G

L

G

V

P

G

V

G

120

121

L

G

V

S

A

G

A

V

P

Q

P

G

A

G

V

K

P

G

K

V

P

G

V

G

L

P

G

V

Y

P

G

V

L

P

G

A

R

F

P

G

V

G

V

L

P

G

V

P

T

G

A

G

V

K

P

K

A

P

180

181

G

V

G

A

F

A

G

I

P

G

V

G

P

F

G

P

Q

P

G

V

P

L

G

Y

P

I

K

A

P

K

L

P

G

Y

G

L

P

Y

T

G

K

L

P

Y

G

Y

G

P

G

V

A

G

A

G

240

241

K

A

G

Y

P

T

G

T

G

V

G

P

Q

A

K

A

K

F

G

A

G

A

G

V

L

P

G

V

G

A

G

V

P

G

V

P

G

A

I

P

G

I

G

I

A

G

V

G

T

300

301

P

A

K

A

K

Y

G

A

G

L

V

P

G

P

G

F

G

P

G

V

G

V

P

G

A

G

V

P

G

V

G

V

P

G

A

G

I

P

V

P

G

A

G

I

P

360

361

G

A

V

P

G

V

S

P

E

A

K

A

K

A

K

Y

G

A

R

P

G

V

G

V

G

I

P

T

Y

G

V

G

A

G

F

P

G

F

G

V

G

V

G

I

P

G

V

A

G

V

420

421

P

G

V

G

V

P

G

V

G

V

P

G

V

G

I

S

P

E

A

Q

A

K

A

K

Y

G

A

G

A

G

V

L

G

L

V

P

G

A

P

G

A

V

P

G

V

P

G

T

G

V

480

481

P

G

V

G

T

P

A

K

A

K

A

Q

F

G

L

V

P

G

V

G

V

A

P

G

V

G

V

A

P

G

V

G

V

A

P

G

V

G

L

A

P

G

V

G

V

A

P

G

V

G

V

A

P

540

541

G

V

G

V

A

P

G

I

G

P

G

V

A

K

S

A

K

V

A

K

A

Q

L

R

A

G

L

G

A

G

I

P

G

L

G

V

G

V

G

V

P

G

L

G

V

G

A

G

V

P

G

L

600

601

G

V

G

A

G

V

P

G

F

G

A

G

A

D

E

G

V

R

S

L

S

P

E

L

R

E

G

D

P

S

Q

H

L

P

S

T

P

S

P

R

V

P

G

A

L

A

K

A

K

Y

G

A

660

661

V

P

G

V

L

G

L

G

A

L

G

V

G

I

P

G

V

G

A

G

P

A

K

A

K

A

Q

F

G

L

V

G

A

G

L

G

L

G

V

G

L

G

V

P

720

721

G

V

G

L

G

I

P

A

K

A

K

Y

G

A

G

L

G

V

L

G

A

G

Q

F

P

L

G

V

A

R

P

G

F

G

L

S

P

I

F

P

G

A

C

L

G

K

A

780

781

C

G

R

K

R

K

786

Amyloidogenic/non-amyloidogenic residues are highlighed in green background.

Charged and Proline residues are highlighed in light red.

Peptide details

Entry:	P-1920
Peptide:	GAAVPGVLGGLGALGGVGIPGGVV
Length:	24
Classification:	Amyloid
Mutation(s):	No
Structure(s):	No structures

Protein Information

UniProt ID:	P15502
UniProt Name:	ELN_HUMAN
Protein Name:	Elastin (Tropoelastin)
Position:	658-681

Literature

PMID:	17929969
Reference:	Biomacromolecules. 2007 Nov;8(11):3478-86.
source:	CPAD

Derived Information

Net Charge:	0
Absolute Charge:	0
Hydrophobicity:	58.33
NuAPRpred:	-3.16
Tango:	1.0

Derived Information (continued)

Normalized Aggregation Propensity (AGGRESCAN):	25.8
Area of the profile Above Threshold (AGGRESCAN):	6.49
Best Energy Score (PASTA 2.0):	-1.34
Aggregate Orientation (PASTA 2.0):	Parallel

Database of known aggregating/non-aggregating peptides

Displaying 1891 to 1920 records out of 2031 records fetched.